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Last Updated: 15 Sep 08
    Diphtheria
    Corynebacterium diphtheriae
 


stain of diphtheria
CDC describes diphtheria as "an upper respiratory tract illness characterized by sore throat, low-grade fever, and an adherent membrane of the tonsil(s), pharynx, and/or nose". Diphtheria is a rapidly developing, acute, febrile infection which involves both local and systemic pathology. A local lesion develops in the upper respiratory tract and involves necrotic injury to epithelial cells. As a result of this injury, blood plasma leaks into the area and a fibrin network forms which is interlaced with with rapidly-growing C. diphtheriae cells.
 
    VIS   SHORTAGES       PACKAGE INSERTS          INFO PAPER

NEWSmore...
dot ABC News 26 Jun 08
Group Advises Adding Multiple Vaccines for Kids

POLICIESmore...
  Individual Medical Readiness (IMR) PDF  03 Jan 06
 Author: Chu
 DoD Instruction 6025.19

CLINICALmore...
  FDA Talk Paper  03 May 05
 First Combination Vaccine Approved to Help Protect Adolescents Against Whooping Cough

ACIP GUIDELINESmore...
  Prevention of Pertussis, Tetanus, and Diphtheria Among Pregnant and Postpartum Women and Their Infants  30 May 08
 Recommendations of the Advisory Committee on Immunization Practices (ACIP)
  Preventing Tetanus, Diphtheria, and Pertussis Among Adults: Use of Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine  15 Dec 06
 Recommendations of the Advisory Committee on Immunization Practices (ACIP) and Recommendation of ACIP, supported by the Healthcare Infection Control Practices Advisory Committee (HICPAC), for Use of Tdap Among Health-Care Personnel
  Preventing Tetanus, Diphtheria, and Pertussis Among Adolescents: Use of Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccines   23 Feb 06
 Recommendations of the Advisory Committee on Immunization Practices (ACIP)

SERVICE MESSAGESmore...
  ALARACT PDF  21 Jan 06
 ADOPTION OF NEW TETANUS-DIPHTHERIA-ACELLULAR PERTUSSIS (TDAP) VACCINE

SHORTAGEmore...
  Resumption of Routine Schedule for Tetanus and Diphtheria Toxoids  21 Jun 02
 MMWR

MMQC MESSAGESmore...
  MMQC-06-1289  07 Sep 06
 SANOFI PASTEUR TEMPORARY SHORTAGE OF ADACEL® VACCINE / UPDATED INFORMATION BULLETIN
  MMQC-06-1235  28 Jul 06
 SANOFI PASTEUR / DECAVAC® VACCINE (TETANUS & DIPHTHERIA TOXOID) / AMERISOURCE BERGEN VOLUNTARY RECALL
  MMQC-06-1219  26 Jul 06
 SANOFI PASTEUR DECAVAC (DIPHTHERIA TOXOID, ADSORBED / TETANUS TOXOID) / VOLUNTARY RECALL / DSCP 06-124

QUESTIONS & ANSWERSmore...
 Diphtheria- The Disease
 Diphtheria- The Vaccine


PACKAGE INSERTmore...
  Kinrix (GlaxoSmithKline)
 DTaP-IPV - Package Insert
  Pentacel (Sanofi-Pasteur)
 DTaP-IPV/Hib - Package Insert
  Daptacel (Sanofi-Pasteur)
 DTaP
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