The Department of Health and Human Services/Program Support Center has a requirement for the Office of Public Health Science/Office on Women’s Health (OWH). Offers will be solicited from all sources through a full and open competition. Offerors should be registered in the Central Contractor Registration (CCR) database for NAICS code 541690 which has a size standard of $6.5 million. The purpose of this requirement is to conduct an evaluation of the Advancing System Improvements to Support Targets for Healthy People 2010 (ASIST2010) program to answer the following evaluation question – Can a public health system/collaborative partnership approach have a positive impact on Healthy People 2010 targets? A public health system is defined as an established collaborative partnership between governmental and non-governmental partners. The OWH implemented the ASIST2010 program in September 2007. The intent of the program is to use a public health systems approach, a sex and gender-based focus, and evidence-based strategies to improve performance on two or more of the seven HP 2010 Focus Areas targeted by this initiative – Cancer, Diabetes, Heart Disease and Stroke, Access to Quality Health Services, Educational and Community-Based Programs, Nutrition and Overweight, and Physical Activity and Fitness – and on at least one objective within each Focus Area. The OWH has 13 very different ASIST2010 programs serving diverse populations and located in diverse organizations. The goals of the ASIST2010 program are to: 1) Support existing public health systems/collaborative partnerships that add a sex and gender focus to the selected HP 2010 Focus Areas and objectives identified above, and 2) Provide additional support to HP 2010 objectives that track the health status of women to help them move towards their targets. It is anticipated that the contract will be for a period of 26 months. This is a presolicitation notice, not a solicitation. Solicitation Number 08T080114 will be made available on Federal Business Opportunities (fedbizopps) website approximately 15 days after publication of this notice. Additionally, all amendments and responses to questions will be posted on the fedbizopps website. No telephone or faxed requests for the solicitation will be accepted.