Guillain-Barre syndrome is a rare disorder that causes your immune system to attack your peripheral nervous system (PNS). The PNS nerves connect your brain and spinal cord with the rest of your body. Damage to these nerves makes it hard for them to transmit signals. As a result, your muscles have trouble responding to your brain. No one knows what causes the syndrome. Sometimes it is triggered by an infection, surgery or a vaccination.
The first symptom is usually weakness or a tingling feeling in your legs. The feeling can spread to your upper body. In severe cases, you become almost paralyzed. This is life-threatening. You might need a respirator to breathe. Symptoms usually worsen over a period of weeks, then stabilize. Most people recover. Recovery can take a few weeks to a few years. Treatment options during the symptom period include medicines or a procedure called plasma exchange.
National Institute of Neurological Disorders and Stroke
Also available in Spanish
Basics | Learn More | Multimedia & Cool Tools |
---|---|---|
|
||
Research | Reference Shelf | For You |
Also available in Spanish
References and abstracts from MEDLINE/PubMed (National Library of Medicine)
Also available in Spanish
Home | Health Topics | Drugs & Supplements | Encyclopedia | Dictionary | News | Directories | Other Resources | |
Disclaimers | Copyright | Privacy | Accessibility | Quality Guidelines U.S. National Library of Medicine, 8600 Rockville Pike, Bethesda, MD 20894 National Institutes of Health | Department of Health & Human Services |
Date last updated: 28 August 2008 Topic last reviewed: 29 August 2008 |