Islet cell transplantation places cells from an organ donor into the pancreas of another person. It is used experimentally to treat type 1 diabetes. Islets are cells found in clusters throughout the pancreas. They are made up of several types of cells. The islets contain beta cells, which make insulin. Insulin is a hormone that helps the body use glucose for energy.
In type 1 diabetes, the beta cells of the pancreas no longer make insulin. A person who has type 1 diabetes must take insulin daily to live. Transplanted islet cells, however, can take over the work of the destroyed cells. Once implanted, the beta cells in these islets begin to make and release insulin. Researchers hope islet transplantation will help people with type 1 diabetes live without daily insulin injections.
National Institute of Diabetes and Digestive and Kidney Diseases
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References and abstracts from MEDLINE/PubMed (National Library of Medicine)
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|Date last updated: 14 July 2008
Topic last reviewed: 09 May 2008