| Treatment Compared | Study, Year | Study Type | Population | Age Range (Yrs) | Study Design | Followup (After Enrollment) | Number (%) of Participants with DSH during Followup | Reported Statistic |
|---|---|---|---|---|---|---|---|---|
| Lithium Use in Week Preceding Suicide or Suicide Attempt vs No Lithium Use | Coryell, et al., 200164 | Nested case-control | Patients treated for major affective disorders identified from 5 academic medical centers; 2 case groups: suicide completers and suicide attempters; controls were matched with cases on sex, polarity at intake, history of substance abuse, and extent of treatment | > 17 | Two case groups (suicide completers and attempters) and 2 matched control groups to evaluate medication use at time of suicidal behavior | Unclear period of time (> 14 yrs) | Lithium use:
Completers: 40.0% Controls of completers: 53.3% Attempters: 22.0% Controls of attempters: 19.5% |
McNemar chi square: 0.667
McNemar chi square: 0.067 |
| Cognitive Behavioral Counseling vs Usual Care | Raj, et al., 200165 | Cohort | Patients who attempted suicide for the first or second time by overdosing on drugs or pesticides who also had anxiety or depression; patients were excluded if they had psychosis, dysthymia, bipolar affective disorder, substance abuse, eating disorder, or personality disorder | 16-50 | Sequential allocation to treatment; intervention: 10 sessions of cognitive
behavioral therapy with mental health professional plus outreach for 3 mos
Control: standard aftercare |
2-3 mos | Intervention: 0/20 (0)
Control: 1/20 (5) |
NA |
Note: DSH, deliberate self-harm; NA, not available. |
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