| Regimen Comparison | Disseminated Mycobacterium avium intracellulare Infection (95% CI) | Mortality (95% CI) | Source, Year (Reference) |
|---|---|---|---|
| Azithromycin vs. placebo | HR, 0.34 (P = 0.004) | HR, 1.02 (P = 0.955) | Oldfield, et al., 1998201 |
| Clarithromycin vs. placebo | HR, 0.31 (CI, 0.18-0.53) | HR, 0.75 (0.58-0.97) | Pierce, et al., 1996202 |
| Rifabutin vs. placebo | RR, 0.43 (0.26-0.70) | RR, 0.68 (0.43-1.06) | Nightingale, et al., 1993 (Studies 023 and 027)203 |
| RR, 0.47 (0.29-0.77) | |||
| Clarithromycin vs. rifabutin | RR, 0.56 (0.37-0.85) | RR, 0.97 (0.78-1.20) | Benson, et al., 2000204 |
| Azithromycin vs. rifabutin | HR, 0.53 (0.34-0.85) | No differences | Havlir, et al., 1996205 |
| Clarithromycin + rifabutin vs. rifabutin | RR, 0.43 (0.27-0.69) | No differences | Benson, et al., 2000204 |
| Azithromycin + rifabutin vs. rifabutin | HR, 0.28 (0.16-0.49) | No differences | Havlir, et al., 1996205 |
| Azithromycin + rifabutin vs. azithromycin | HR, 0.53 (0.29-0.95) | No differences | Havlir, et al., 1996205 |
| Clarithromycin + rifabutin vs. clarithromycin | RR, 0.79 (0.48-1.31) | No differences | Benson, et al., 2000204 |
aNotes: HR = hazard ratio; RR = relative risk.