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Chiu WA, Okino MS, Lipscomb JC, Evans MV.
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Issues in the pharmacokinetics of trichloroethylene and its metabolites.
Environ Health Perspect. 2006 Sep;114(9):1450-6. Review.
PMID: 16966104 [PubMed - indexed for MEDLINE]
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Chiu WA, Caldwell JC, Keshava N, Scott CS.
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Key scientific issues in the health risk assessment of trichloroethylene.
Environ Health Perspect. 2006 Sep;114(9):1445-9. Review.
PMID: 16966103 [PubMed - indexed for MEDLINE]
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Fisher JW.
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Physiologically based pharmacokinetic models for trichloroethylene and its oxidative metabolites.
Environ Health Perspect. 2000 May;108 Suppl 2:265-73. Review.
PMID: 10807557 [PubMed - indexed for MEDLINE]
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Caldwell JC, Keshava N.
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Key issues in the modes of action and effects of trichloroethylene metabolites for liver and kidney tumorigenesis.
Environ Health Perspect. 2006 Sep;114(9):1457-63. Review.
PMID: 16966105 [PubMed - indexed for MEDLINE]
5:
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Allen BC, Fisher JW.
Abstract
Pharmacokinetic modeling of trichloroethylene and trichloroacetic acid in humans.
Risk Anal. 1993 Feb;13(1):71-86.
PMID: 8451462 [PubMed - indexed for MEDLINE]
6:
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Fisher JW, Mahle D, Abbas R.
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A human physiologically based pharmacokinetic model for trichloroethylene and its metabolites, trichloroacetic acid and free trichloroethanol.
Toxicol Appl Pharmacol. 1998 Oct;152(2):339-59.
PMID: 9853003 [PubMed - indexed for MEDLINE]
7:
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Clewell HJ, Andersen ME.
Abstract
Applying mode-of-action and pharmacokinetic considerations in contemporary cancer risk assessments: an example with trichloroethylene.
Crit Rev Toxicol. 2004 Sep-Oct;34(5):385-445. Review.
PMID: 15560567 [PubMed - indexed for MEDLINE]
8:
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Keshava N, Caldwell JC.
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Key issues in the role of peroxisome proliferator-activated receptor agonism and cell signaling in trichloroethylene toxicity.
Environ Health Perspect. 2006 Sep;114(9):1464-70. Review.
PMID: 16966106 [PubMed - indexed for MEDLINE]
9:
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Abbas R, Fisher JW.
Abstract
A physiologically based pharmacokinetic model for trichloroethylene and its metabolites, chloral hydrate, trichloroacetate, dichloroacetate, trichloroethanol, and trichloroethanol glucuronide in B6C3F1 mice.
Toxicol Appl Pharmacol. 1997 Nov;147(1):15-30.
PMID: 9356303 [PubMed - indexed for MEDLINE]
10:
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Lash LH, Fisher JW, Lipscomb JC, Parker JC.
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Metabolism of trichloroethylene.
Environ Health Perspect. 2000 May;108 Suppl 2:177-200. Review.
PMID: 10807551 [PubMed - indexed for MEDLINE]
11:
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Cronin WJ 4th, Oswald EJ, Shelley ML, Fisher JW, Flemming CD.
Abstract
A trichloroethylene risk assessment using a Monte Carlo analysis of parameter uncertainty in conjunction with physiologically-based pharmacokinetic modeling.
Risk Anal. 1995 Oct;15(5):555-65.
PMID: 7501875 [PubMed - indexed for MEDLINE]
12:
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Scott CS, Chiu WA.
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Trichloroethylene cancer epidemiology: a consideration of select issues.
Environ Health Perspect. 2006 Sep;114(9):1471-8. Review.
PMID: 16966107 [PubMed - indexed for MEDLINE]
13:
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Yang RS, el-Masri HA, Thomas RS, Constan AA, Tessari JD.
Abstract
The application of physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) modeling for exploring risk assessment approaches of chemical mixtures.
Toxicol Lett. 1995 Sep;79(1-3):193-200. Review.
PMID: 7570656 [PubMed - indexed for MEDLINE]
14:
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Clewell HJ 3rd, Gentry PR, Covington TR, Gearhart JM.
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Development of a physiologically based pharmacokinetic model of trichloroethylene and its metabolites for use in risk assessment.
Environ Health Perspect. 2000 May;108 Suppl 2:283-305. Review.
PMID: 10807559 [PubMed - indexed for MEDLINE]
15:
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Greenberg MS, Burton GA, Fisher JW.
Abstract
Physiologically based pharmacokinetic modeling of inhaled trichloroethylene and its oxidative metabolites in B6C3F1 mice.
Toxicol Appl Pharmacol. 1999 Feb 1;154(3):264-78.
PMID: 9931286 [PubMed - indexed for MEDLINE]
16:
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Keys DA, Bruckner JV, Muralidhara S, Fisher JW.
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Tissue dosimetry expansion and cross-validation of rat and mouse physiologically based pharmacokinetic models for trichloroethylene.
Toxicol Sci. 2003 Nov;76(1):35-50. Epub 2003 Aug 12.
PMID: 12915716 [PubMed - indexed for MEDLINE]
17:
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Stenner RD, Merdink JL, Fisher JW, Bull RJ.
Abstract
Physiologically-based pharmacokinetic model for trichloroethylene considering enterohepatic recirculation of major metabolites.
Risk Anal. 1998 Jun;18(3):261-9.
PMID: 9664722 [PubMed - indexed for MEDLINE]
18:
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Caldwell JC, Evans MV, Marcus AH, Scott CS, Chiu WA, Okino MS, Preuss PW.
Abstract
Comments on article "Applying mode-of-action and pharmacokinetic considerations in contemporary cancer risk assessments: an example with trichloroethylene" by Clewell and Andersen.
Crit Rev Toxicol. 2006 Mar;36(3):291-4; discussion 295-8.
PMID: 16686425 [PubMed - indexed for MEDLINE]
19:
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Hack CE, Chiu WA, Jay Zhao Q, Clewell HJ.
Abstract
Bayesian population analysis of a harmonized physiologically based pharmacokinetic model of trichloroethylene and its metabolites.
Regul Toxicol Pharmacol. 2006 Oct;46(1):63-83. Epub 2006 Aug 4.
PMID: 16889879 [PubMed - indexed for MEDLINE]
20:
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Moore MM, Harrington-Brock K.
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Mutagenicity of trichloroethylene and its metabolites: implications for the risk assessment of trichloroethylene.
Environ Health Perspect. 2000 May;108 Suppl 2:215-23. Review.
PMID: 10807553 [PubMed - indexed for MEDLINE]
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