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New Grant Supports Stem Cell-Derived Model of Autism-Related Illness
June 26, 2008 • Science Update
For the first time, researchers are developing a test tube model of Rett syndrome, a debilitating autism-like illness, in neurons derived from human embryonic stem cells. The study, recently funded by a grant from NIMH’s Division of Neuroscience and Basic Behavioral Science, addresses a crucial gap in understanding the workings of the rare autism spectrum disorder.
Antipsychotic Medications May Ease Some Alzheimer’s Symptoms, Not Others
June 23, 2008 • Science Update
Antipsychotic medications may lessen symptoms like hostility and aggression in patients with Alzheimer’s disease, but do not appear to lessen other symptoms or improve quality of life, according to a recent analysis of data from the NIMH-funded Clinical Antipsychotic Trials of Intervention Effectiveness Alzheimer’s Disease (CATIE-AD) study. The analysis was published online ahead of print June 2, 2008, in the American Journal of Psychiatry.
New Grant Aims to Overcome Obesity in People with Serious Mental Illness
June 20, 2008 • Science Update
A new grant funded by NIMH will test the effectiveness of a promising intervention designed to help people with serious mental illness (SMI) who are overweight or obese lose weight and keep it off.
Anxious Youth Have Disturbed Brain Responses When Looking at Angry Faces
June 20, 2008 • Science Update
When looking at angry faces so quickly that they are hardly aware of seeing them, youth with generalized anxiety disorder (GAD) have unchecked activity in the brain’s fear center, say NIMH researchers.
Potential New Target Found for Developing Medications to Treat Bipolar Disorder
June 20, 2008 • Science Update
Medications that target the protein BAG1, which regulates a process that can trigger symptoms in people who have bipolar disorder, may offer a new way of treating the disease, according to NIMH scientists.
The Maturing Brain Parallels its Evolution
June 5, 2008 • Science Update
Evolutionarily older areas of the human brain that mature earliest follow a simple, straight-line growth pattern. In contrast, newer areas that support our uniquely human capacities, such as thinking and language, mature latest and show the most complex growth pattern, NIMH researchers say. In keeping with their relatively recent evolution, newer areas are composed of more complex layers of cells and show stronger genetic influence later in development compared with evolutionarily older areas.
New NIMH Research to Test Innovative Treatments for Children with ADHD
June 5, 2008 • Science Update
Two new grants funded by NIMH will focus on novel and innovative approaches to treating children who have attention deficit hyperactivity disorder (ADHD).
NIMH Funds Research to Find Best Treatments for Children with Autism and ADHD Symptoms
June 2, 2008 • Science Update
A new NIMH-funded study will help guide the treatment of attention deficit hyperactivity disorder (ADHD) symptoms in children with autism spectrum disorders (ASD). ADHD symptoms are common in children with ASD, but children with ASD often do not respond well to stimulant medications, the conventional treatment for ADHD.
Spontaneous Mutations Rife in Non-Familial Schizophrenia
May 30, 2008 • Press Release
People with schizophrenia from families with no history of the illness were found to harbor eight times more spontaneous mutations – most in pathways affecting brain development – than healthy controls, in a study supported in part the National Institutes of Health’s (NIH) National Institute of Mental Health (NIMH). By contrast, no spontaneous mutations were found in people with schizophrenia who had family histories of the illness.
Preventive Treatment May Help Head Off Depression Following a Stroke
May 28, 2008 • Science Update
For the first time, researchers show that preventive treatment with an antidepressant medication or talk therapy can significantly reduce the risk or delay the start of depression following an acute stroke, according to a study funded by the National Institute of Mental Health (NIMH).
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