Drug Tools

Clinical Trials Database (AIDSinfo)
Clinical trials are research studies designed to answer specific questions about the safety and/or effectiveness of drugs, vaccines, other therapies, or new ways of using existing treatments. This page is designed to help you locate trials studying HIV/AIDS. En español

Drug Database (AIDSinfo)
The AIDSinfo Drug Database provides fact sheets on HIV/AIDS related drugs. The fact sheets describe the drug's use, pharmacology, side effects, and other information. The database includes approved and investigational HIV/AIDS related drugs and three versions of each fact sheet: patient, health professional, and Spanish. En español

Expanded Access and Expedited Approval (Food and Drug Administration)
FDA has taken significant steps in response to the HIV/AIDS crisis toward making experimental drugs intended to treat life-threatening diseases more widely available to severely ill patients, as well as toward speeding the review and approval of the applications for these products. This resource provides information on these efforts.

MedWatch (Food and Drug Administration)
MedWatch is an Internet gateway for timely safety information on drugs and other medical products regulated by the FDA. The Medwatch program enhances the effectiveness of postmarketing surveillance of medical products as they are used in clinical practice, helping to rapidly identify significant health hazards associated with these products.

Resources for Clinicians – Antiretroviral Reference Tables (AIDS Education and Training Centers, HRSA)
This resource provides tables from AETC’s Clinical Manual for Management of the HIV-Infected Adult. This manual’s tables include content regarding Drug Characteristics, Regimen Selection, Drug Interactions, Adverse Effects, and Special Situations.

Guidelines

Clinical Guidelines Portal (AIDSinfo)
Guidelines for antiretroviral treatment, maternal-child transmission, post-exposure prophylaxis, management of HIV complications, and testing are available from this resource. The clinical guidelines are updated regularly by a panel of HIV experts.

Adult and Adolescent Treatment Guidelines (AIDSinfo)
U.S. Department of Health and Human Services (HHS) Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents. These guidelines outline current understanding of how clinicians should use antiretroviral drugs to treat adults and adolescents with HIV infection. The primary areas of attention within these guidelines include when to initiate therapy, which drug combinations are preferred and which drugs or combinations should be avoided, and means to continue clinical benefit in the face of antiretroviral drug resistance. New evidence is considered periodically and the adjustments are made to recommendations accordingly.

Clinical Guide on Supportive and Palliative Care for People with HIV/AIDS (HIV/AIDS Bureau, HRSA)
Palliative care is patient- and family-centered care that optimizes quality of life by active anticipation, prevention, and treatment of suffering. Palliative care is supportive of the clinical care patients with HIV/AIDS should be receiving in a health-care setting. These guidelines were created to define the goals of palliative care for the long-term treatment of people living with HIV/AIDS

Guide to Primary Care for People with HIV/AIDS (HIV/AIDS Bureau, HRSA)
This guide is addresses many important aspects of HIV/AIDS care and treatment and provides best practices to help people live longer and healthier with HIV/AIDS. Recommended references and citations are provided for the reader to be able to access in-depth information on topics that are particularly important and/or controversial.

Guide to the Clinical Care of Women with HIV/AIDS (HIV/AIDS Bureau, HRSA)
This guide addresses many important aspects of HIV/AIDS care and treatment and provides best practices specific to the unique treatment issues that relate to the treatment of women with HIV/AIDS. Recommended references and citations are provided for the reader to be able to access in-depth information on topics that are particularly important and/or controversial.

Managing Drug Interactions in the Treatment of HIV-Related Tuberculosis (Centers for Disease Control and Prevention)
The purpose of this summary is to provide the clinician with updated recommendations for managing the drug-drug interactions that occur when using antiretroviral therapy during tuberculosis treatment.

Pediatric Guidelines (AIDSinfo)
Guidelines for treating HIV infected infants, children, and adolescents, including clinical monitoring, initiation of treatment, pediatric-specific drug information, and managing complications, written by the United States Public Health Service and the Infectious Disease Society of America.

Prevention of Opportunistic Infections Guidelines (AIDSinfo)
Guidelines for the prevention of opportunistic infections in persons with HIV, written by the United States Public Health Service.

Sexually Transmitted Diseases Treatment Guidelines 2006 (Centers for Disease Control and Prevention)
These guidelines for the treatment of STDs are intended to assist physicians and other health-care providers with the effort to prevent and treat sexually transmitted diseases. Although these guidelines emphasize treatment, prevention strategies and diagnostic recommendations also are discussed. Several sections of this document focus on HIV transmission prevention, prevention in specific populations, and testing, referral, and counseling information.

Treatment of Opportunistic Infections Guidelines (AIDSinfo)
These guidelines provide evidence-based information for the treatments of 28 opportunistic infections in HIV-infected adults and adolescents. The guidelines are written by the Centers for Disease Control, the National Institutes of Health and the HIV Medicine Association/Infectious Diseases Society of America. Fact Sheets [update wireframes to reflect new content area]

Fact Sheets

Adhering to My HIV Treatment Regimen (PDF - 54 KB)(AIDSinfo)
Fact sheet with suggestions on how to maintain adherence to an anti-HIV drug regimen. En español (PDF - 58 KB)

Available Anti-HIV Medications (PDF - 116 KB) (AIDSinfo)
Fact sheet with all available anti-HIV medications, in generic and brand name listed in table format. En español (PDF - 135 KB) [http://aidsinfo.nih.gov/ContentFiles/AntirretroviralescontralainfeccionporelVIH_FS_sp.pdf]

Changing My HIV Treatment Regimen (PDF - 56 KB) (AIDSinfo)
Fact sheet with information on how and why a doctor may recommend a change in treatment for an HIV infected person currently receiving drug therapy. En español (PDF - 68 KB)

HIV Treatment Regimen Failure (PDF - 55 KB) (AIDSinfo)
Fact sheet with information on the types of treatment failure HIV infected people may experience after taking anti-HIV medications for a period of time. En español (PDF - 57KB)

Is My Treatment Regimen Working? (PDF - 56 KB) (AIDSinfo)
Fact sheet with information on how HIV infected people currently on drug therapy and their doctors can assess the success or failure of treatment. En español (PDF - 69 KB) [http://aidsinfo.nih.gov/ContentFiles/EstaFuncionandoMiRegimenTerapeutico_FS_sp.pdf]

Recommended HIV Treatment Regimens (PDF - 60 KB) (AIDSinfo)
Fact sheet listing the currently approved regimens from the Federal treatment guidelines. En español (PDF - 71 KB)

Starting Anti-HIV Medications (PDF - 54 KB) (AIDSinfo)
Fact sheet with information for an HIV infected person starting anti-HIV drug therapy for the first time. En español ( PDF - 66 KB)

Treatment of HIV Infection (National Institute of Allergy and Infectious Diseases, NIH)
A fact sheet about approved HIV medications and research into new medications.

Treatment Regimens for HIV Positive Pregnant Women (PDF - 54 KB) (AIDSinfo)
Fact sheet with information on drug regimens that an HIV infected pregnant woman may take to preserve her health and prevent transmission of HIV to her baby. En español (PDF - 135 KB)

What is Treatment Adherence? (PDF - 54 KB) (AIDSinfo)
Fact sheet explaining what adherence to a drug regimen is and its importance in HIV treatment. En español (PDF - 66 KB)