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Cat Genome Project

American Genetic Association

Laboratory of Genomic Diversity/National Cancer Institute

The Smithsonian Institution’s Conservation & Research Center

announce a course

RECENT ADVANCES IN CONSERVATION GENETICS

August 17-30, 2002

At the Smithsonian Institution's Conservation & Research Center in Front Royal, Virginia, outside Washington, DC, the AGA and the LGD are presenting a two-week intensive course in methods, interpretation, and applications of molecular genetic analyses for conservation of endangered species.  This course will be taught by scientists with expertise and a variety of personal experiences in this important field.  Participants will learn how to develop and interpret a wide range of genetic data using real examples, laboratory demonstrations and a variety of computer programs.

COURSE DIRECTOR: Stephen J. O'Brien, Chief of the Laboratory of Genomic Diversity, National Cancer Institute, Frederick, Maryland, USA

FACULTY:  The 2002 faculty is being assembled, but previous faculty has included such pioneers in conservation genetics as:

John Avise (University of Georgia), Scott Baker (University of Auckland), Jon Ballou (National Zoological Park), Brian Bowen (University of Florida), Mitchell Bush (CRC), Mike Clegg (U. of California-Riverside), David Coltman (U. of Sheffield), Susie Ellis (CBSG), Rob Fleischer (National Zoological Park), Richard Frankham (Macquarie University), Bruce Grant (College of William & Mary), Phil Hedrick (Arizona State University), David Goldstein (Oxford University), Marshall Jones (Department of the Interior, USFWS), Sue Lieberman (USFWS), Phil Morin (Max Planck Institute for Evolutionary Anthropology), Steve Palumbi (Harvard University), Oliver Ryder (CRES, Zoological Society of San Diego), Barbara Schall (Washington University), Ulysses S. Seal (CBSG), Paul Sharp (University of Nottingham), David Swofford (Smithsonian Institution), Blaire Van Valkenburgh (UCLA), Robert Wayne (UCLA), Chris Wemmer (CRC), David Wildt (CRC), David Woodruff (UCSD)

In addition: Renata McCarthy and Peter Cooper  (National Center for Biotechnology Information) and members of the Laboratory of Genomic Diversity, National Cancer Institute-Frederick: Victor David, Warren Johnson, Bill Murphy, Steve O’Brien, Marilyn Raymond, Melody Roelke, Jill Slattery

TOPICS include:

Sample collection and processing
PCR-based technologies for polymorphism detection
Genetic analysis:

o        Bioinformatics and the use of molecular genetic databases

o        Estimating relative genetic diversity with gene markers

o        Phylogenetic algorithms: their use and interpretation

o        Phylogeography

o        Subspecies and population substructure

o        Demographic and genetic simulation modeling of small populations

o        Kinship and paternity assessment

Host-pathogen interactions
Conservation management applications

TUITION:  US $2,000 (includes housing, meals, and Dulles International Airport transfers)

To apply, see application procedures below.  Follow the mailing instructions on the form.

Deadline for receipt of applications: March 15, 2002
Admission is competitive.  Participants in this course will be limited to 24.
Limited financial aid is available.

Frequently Asked Questions

1. What is Conservation Genetics?

As an applied science, Conservation Genetics utilizes concepts, theories and methods of more traditionally defined fields, but also adds to our knowledge of these fields:

genetics
ecology
behavior
physiology
molecular biology
evolution
demography

One of the primary objectives of Conservation Genetics is to develop effective management strategies for the conservation of threatened species or populations. These strategies should consider and include:

·         past and current status, as well as future prospects of a population or species

·         efforts to preserve genetic diversity

·         efforts to preserve evolutionary processes such as hybridization and speciation

2. What is the purpose of this course?

The goal of RECENT ADVANCES IN CONSERVATION GENETICS is to teach the participants how to develop and interpret a variety of genetic data in order to answer specific questions regarding endangered taxa.  We present an overview of molecular techniques available for pursuing population, taxonomic and phylogenetic questions, with special emphasis on PCR-based technologies for DNA polymorphism detection and computer programs for analysis of molecular genetic data.  Guest lecturers present case histories exemplifying application of conservation genetics.  We found during previous courses that students learn a great deal from each other as well as from faculty because of shared interests in conservation and a common goal of applying conservation genetics in the management of endangered species.

3. Who should apply for this course?

We welcome applications from conservation-minded scientists (advanced graduate students, post-docs, teachers, and researchers with advanced degrees) of any nationality from academia, government, NGOs, or industry who are studying the genetics of endangered species and who will apply the knowledge gained from this course to the conservation of such species.

4. How do I apply?

Print the application  form or request an application from the course coordinator,

Ms. Jan Martenson, NCI/FCRDC
P.O. Box B
Frederick, MD 21702-1201

Phone: 301/846-1296; FAX 301/846-6327; email:  noahscrc@ncifcrf.gov

Complete the forms in black ink or by typing.
No electronic submissions, please – delivery by mail is preferred, but faxes are acceptable if fully legible.
A complete application package comprises:

1)       Admissions Application form

2)       One-page Curriculum Vitae

3)       One-page summary or abstract of ongoing or future research project(s)

4)       A brief statement of what is expected to be gained from the course and how you will apply what you learn

5)       OPTIONAL:  Financial Aid Request Form

Notification of receipt of the application materials will be sent by email shortly after the application package arrives.

5. How are the participants selected?

The Admissions Committee evaluates and selects 24 participants based on information provided in the applications and required attachments.  This is always a difficult task in view of the large number of well-qualified persons who apply.  Positions are typically offered to those whose application materials convey that they will make the best use of, and most benefit from, this course.  Request for financial aid is not a factor in admission decisions.

6. When will those selected to participate be notified of acceptance?

Applicants will receive the decision by the Admissions Committee in early April by email with a follow-up letter.  Actions will be:  admit; wait-list; or not recommended for admission.  Those who are admitted will be asked to confirm their participation in the course by June 1 with a 50% deposit.  Should any accepted candidate(s) be unable to attend, the first person(s) on the waiting list will be notified in early June.

7. What is the cost of the course and when/how is it paid?

US$2,000 includes housing and meals at the CRC and ground transportation to/from Dulles International Airport.  If accepted, attendance must be confirmed by June 1 with a 50% deposit of the course cost. The balance will be due before or on the first day of the course, August 17. Payment by checks is preferred, but electronic transfer of funds is possible.  We cannot accept credit cards for payment.

8. Is financial aid available? How do I apply?

Limited financial aid is available in the form of partial scholarships granted by the American Genetic Association and will be awarded on the basis of need.  Those wishing to be considered for assistance must submit the Financial Aid form with their application package.

9.  Where is the course held and what is the structure?

The CRC is 2.5 miles south of Front Royal, Virginia (50 miles SW of Dulles International Airport and about 70 miles west of Washington DC) in the beautiful piedmont region of the Blue Ridge Mountains.  The Shenandoah National Park and the Appalachian Trail border the CRC property.  The CRC Conference/Training Center’s accommodations are comfortable, air-conditioned, dormitory-style rooms (participants share a room with one other person).  All meals will be provided and served in the dining room of the training center.

Generally, the morning sessions will be lectures in the CRC auditorium.  Afternoon sessions will be a mix of demonstrations, "hands-on” labs and computer labs, held either in the research building or in the training center.  Evenings usuallly feature a plenary lecturer after dinner.  There will one free day.

  Sponsors:

AMERICAN GENETIC ASSOCIATION

The AGA is the world’s oldest genetics society, founded in 1914 to advance the knowledge and applications of the growing field of genetics.  Today the AGA remains committed to the advancement of organismal genetics and genome diversity using the most advanced technologies and computational theory.  The parent scientific publication, the Journal of Heredity, embodies these principles of scientific excellence including a strong commitment to Conservation.  In this new millennium the AGA has generously agreed to provide scholarships for “Recent Advances in Conservation Genetics.”

THE Laboratory of Genomic Diversity

The LGD is part of the Center for Cancer Research at the National Cancer Institute-Frederick, Maryland.  Led by Dr. Stephen J. O’Brien, the lab is world-renowned for contributions to the fields of human genetic diversity (primarily in discoveries of genetic factors controlling susceptibility to cancers and viral diseases), feline gene mapping, and conservation genetics of the Felidae family. 

THE CRC

The Conservation & Research Center (CRC) of the National Zoological  Park/Smithsonian Institution is dedicated exclusively to biodiversity conservation, education, and training.

CRC scientists and their collaborators at the National Zoo, the National Cancer Institute, and the Smithsonian combine an uncommon range of skills for addressing complex conservation issues, for generating sound scientific data for decision makers, and for training the conservation leaders of tomorrow.  These activities reach far beyond the Washington, DC, area with international training programs, "mobile laboratories," and research and education projects ongoing throughout the world.  At the same time, long-term studies at CRC itself are unraveling the ecological mysteries of the Virginia Piedmont and eastern deciduous forests.

Cutting-edge technologies in ecology, veterinary medicine, genetics, and the reproductive sciences allow CRC to stand in the forefront of local, national and international efforts to protect endangered species and habitats. Success is based on partnerships -- with other conservation and educational organizations, universities, government and non-governmental entities, and local communities.

The scientific achievements are numerous. They include helping breed the endangered black-footed ferret for reintroduction into the American West; producing cheetahs, tigers and scimitar-horned oryx using reproductive technologies originally developed for humans; studying viruses in lions to help understand HIV infection in humans; and studying migratory patterns in song birds and the status of their North American habitats -- our local forest.

More than a thousand alumni of CRC training programs and courses are now advancing environmental causes around the world as scientists, policy makers, wildlife authorities, and educators.  Scholarly productivity is emphasized - technical publications convey new discoveries to the scientific community while books popularize conservation and science for the lay public.  Of particular significance is the use of this new knowledge to enlighten and excite children, the conservationists of the new millennium.

This course has been supported in the past by British Airways, Applied Biosystems Division of Perkin Elmer, Apple Computers, Life Science International, MJ Research Inc., NOVEX, Stratagene and Pharmacia-Hoeffer Biotech.  

Comments from past participants:

“It was one of the best educational experiences of my life.  The material learned and exposure to the many dimensions of conservation genetics will be invaluable to me…. The facility at the CRC was very pleasant and especially conducive to learning.  The researchers/faculty …and invited plenary lecturers were extraordinary.” – John Pierce (’00), Chief Wildlife Scientist and PhD candidate, Washington Department of Fish & Wildlife.

"The setting at the Conservation & Research Center was perfect and very conducive to learning.  However, the content of the course and quality of the instructors far exceeded my expectations.  I return to my laboratory excited and enthused to apply this new knowledge to my field of marine ecology." - Paul Montagna (’97), PhD, Associate Professor, Marine Science Institute, University of Texas, Port Aransas

“The course exceeded my expectations in terms of material covered, and the excellent instruction given by the people in the field.  Most importantly, I met like-minded students and professors… the course represented a turning point in my career…” - Ravinder Sehgal (’98), PhD., Stockholm, Sweden.

"It has been an enormous experience to learn updated methodologies and techniques, as well as current issues related to conservation genetics research ... The organization of the course was just great..."- R. Eduardo Palma (’96), PhD., University of Chile

"This course will greatly enhance my effectiveness as a teacher... The material I learned...will also greatly strengthen my ability to excite the students about the importance of wildlife conservation." - Lisa Muller (’97), PhD, Assistant Professor, Delaware State University

“I’ve come away…feeling truly inspired.  The diversity of instruction and presentations offered during the course provided me with many tools that I will use to address the hypotheses I am currently testing using genetic data.” –Gail Blundell (’98), PhD. Student/Research Assistant, Alaska Cooperative Fish & Wildlife Research Unit

"The course in one word has been overwhelming. The scope of the program was very comprehensive; in my opinion instrumental in positioning one's own research project in this highly interdisciplinary field." - Paul Wenink (’97), PhD., Post-doctoral researcher, Wageningen Agricultural University, The Netherlands

"I learnt [sic] more in those two weeks than I would have ever thought possible..., was given so many new ideas that I'll be busy for at least the next twenty years..., and best of all, had the opportunity to meet and get to know the most fantastic group of like-minded people...!" - Merel Dalebout (’96), PhD. Student, University of Auckland, New Zealand  

Last Updated on December 18, 2001 by S. Palmer