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Drug Dosing Toolkit

Prezista (darunavir, TMC-114)

Type of Drug: Protease Inhibitor (PI)

Approved adult dosing

one 600 mg tablet Prezista + one 100 mg capsule Norvir, two times a day

  • Morning

    Prezista 600Prezista 600

    Prezista

    +
    Norvir 100

    Norvir

  • Evening

    Prezista 600Prezista 600

    Prezista

    +
    Norvir 100

    Norvir

Note: Prezista has been available as a 300 mg tablet (dose is two 300 mg tablets + one 100 mg capsule Norvir, two times a day), but this is being phased out.

My doctor's instructions

Notes on taking this medication

  • Must take Prezista with Norvir; it is approved only with the use of Norvir
  • Must take with food
  • Prezista interacts with many other drugs; persons using Prezista with those drugs may need an adjustment to their dose of Prezista or the other drugs; consult your medical provider

Side effects

  • Nausea; diarrhea; stomach discomfort
  • Rash
  • Liver inflammation and increased liver enzyme levels
  • Elevations in cholesterol and triglycerides
  • Elevated blood sugar
  • Abnormal accumulation of body fat
  • Persons who are allergic to sulfa drugs may be allergic to Prezista