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- New Research to Help Youth with Mental Disorders Transition to Adulthood
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September 5, 2007
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Science Update
As young people with mental health disorders transition from adolescence to adulthood, they frequently face new and difficult challenges such as the loss of state-issued benefits like Medicaid and foster care, or loss of family-based insurance coverage. Unfortunately, many are not prepared for the abrupt transition and may not be able to effectively manage their disorder on their own.
- Studies Refine Understanding of Treatments for Bipolar Disorder
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September 1, 2007
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Science Update
Two new studies provide additional details on best practices for treating people with bipolar disorder, a sometimes debilitating illness marked by severe mood swings between depression and mania. The two studies are part of the NIMH-funded Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD).
- New Technique Pinpoints Crossroads of Depression in Rat Brain
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August 2, 2007
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Science Update
NIMH-funded scientists have developed a new high-speed technique for imaging brain activity and used it to pinpoint a circuit signal in rats that may be at the crossroads of depression.
- Success or Failure of Antidepressant Citalopram Predicted by Gene Variation
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August 1, 2007
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Press Release
A variation in a gene called GRIK4 appears to make people with depression more likely to respond to the medication citalopram (Celexa) than are people without the variation, a study by NIMH has found.
- Faster-Acting Antidepressants Closer to Becoming a Reality
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July 24, 2007
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Press Release
A new study has revealed more about how the medication ketamine, when used experimentally for depression, relieves symptoms of the disorder in hours instead of the weeks or months it takes for current antidepressants to work.
- Improvement Following ADHD Treatment Sustained in Most Children
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July 20, 2007
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Press Release
Most children treated in a variety of ways for attention deficit hyperactivity disorder (ADHD) showed sustained improvement after three years in a major follow-up study funded by NIMH.
- In Second Try to Treat Depression, Cognitive Therapy Generally As Effective As Medication
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May 1, 2007
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Science Update
Switching to or adding cognitive therapy (CT) after a first unsuccessful attempt at treating depression with an antidepressant medication is generally as effective as switching to or adding another medication, but remission may take longer to achieve.
- Intensive Psychotherapy More Effective Than Brief Therapy for Treating Bipolar Depression
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April 2, 2007
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Press Release
Patients taking medications to treat bipolar disorder are more likely to get well faster and stay well if they receive intensive psychotherapy, according to results from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD), funded by NIMH.
- Study Sheds Light on Medication Treatment Options for Bipolar Disorder
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March 28, 2007
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Press Release
For depressed people with bipolar disorder who are taking a mood stabilizer, adding an antidepressant medication is no more effective than a placebo (sugar pill), according to results published online on March 28, 2007 in the New England Journal of Medicine.
- Landmark Council Session Spotlights “Real World” Trials
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December 21, 2006
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Science Update
Principal investigators of NIMH's four large-scale clinical trials presented study results and their implications at the National Advisory Mental Health Council meeting on September 15, 2006.
