Miller, D.S., Bauer, B., Hartz, A.M.S. Modulation of p-glycoprotein at the blood-brain barrier: opportunities to improve CNS pharmacotherapy. Pharmacol. Rev., 60:196-209, 2008.
[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18560012 )
Fricker, G., Nobmann, S., and Miller, D.S. Permeability of porcine blood brain barrier to somatostatin anlogs. Brit. J. Pharmacol., 135:1308-1314, 2002. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11877340)
Breen, C., Sykes, D.B., Fricker, G. and Miller, D.S. Confocal imaging of organic anion transport in intact rat choroid plexus. Am. J. Physiol., 282:F877-F885, 2002. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11934698)
Sweet, D.H., Miller, D.S., Pritchard, J.B., Fujiwara, Y., Beier, D.R., and Nigam, S.K. Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3/|Slc22a8|) knockout mice. J. Biol. Chem., 277:26934-26943, 2002. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12011098)
Fellner, S., Bauer, B., Miller, D.S., Schaffrik, M., Spruß, T., Bernhardt, G., Graeff, C., Färber, L., Gschaidmeier, H., Buschauer, A., Fricker, G. Transport of Paclitaxel (Taxol) across the blood-brain barrier in vitro and in vivo. J. Clin. Invest.110:1309-1318, 2002. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12417570)
Sweet, D.H., Chan, L.M.S., Walden, R., Yang, X.-P., Miller, D.S. and Pritchard, J.B. Organic anion transporter 3 [Slc22a8] is a dicarboxylate exchanger indirectly coupled to the Na+ gradient. Am. J. Physiol, 284:F763-F769, 2003. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12488248)
Miller, D.S. Confocal imaging of xenobiotic transport across the blood-brain barrier. J. Exp. Zool., 300:84-90, 2003. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14598390)
Erdlenbruch, B., Alippour, M., Miller, D.S., Kugler, W., Eibl, H., and Lakomek, M. Alkylglycerol opening of the blood-brain barrier to small and large fluorescence markers in normal and C6 glioma bearing rats and isolated rat brain capillaries. Brit. J. Pharmacol., 140:1201-1210, 2003. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14597599)
Sykes, D., Sweet, D.H., Lowes, S., Nigam, S.J., Pritchard, J.B., and Miller, D.S. Organic Anion Transport in Choroid Plexus From Wild-Type and Organic Anion Transporter 3 (Slc22a8)-Null Mice. Am. J. Physiol., 286:F972-8, 2004. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15075193)
Breen, C.M., Sykes, D.B., Baehr, C., Fricker, G., and Miller D.S. Fluorescein-Methotrexate Transport in rat choroid plexus analyzed using confocal microscopy. Am. J. Physiol., 287:F562-F569, 2004. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15126245)
Bauer, B., Hartz, A.M.S., Fricker, G., and Miller D.S. Pregnane X receptor upregulation of p-glycoprotein expression and transport function at the blood-brain barrier. Mol. Pharmacol., 66:413-419, 2004. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15322232)
Hartz, A.M.S., Bauer, B., Fricker, G., and Miller D.S. Rapid regulation of p-glycoprotein at the blood-brain barrier by endothelin-1. Mol. Pharmacol., 66:387-394, 2004. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15322229)
Miller, D.S. Confocal imaging of xenobiotic transport across the choroid plexus. Adv. Drug Delivery Rev., 56:1811-1824, 2004. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15381335)
Bauer, B., Hartz, A.M.S., Fricker, G., and Miller D.S. Modulation of p-glycoprotein transport function at the blood-brain barrier. Experimental Biology and Medicine, 230:118-27, 2005. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15673560)
Pritchard, J.B., and Miller, D.S. Expression systems for cloned polyspecific xenobiotic transporters. Toxicol. Appl. Pharmacol., 204:256-262, 2005. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15845417)
Lowes, S., Sykes, D., Breen, C.R.,, Ragone, L.J., and Miller, D.S. Multiple components of 2,4-dichlorophenoxyacetic acid uptake by rat choroid plexus. J. Pharmacol. Exp. Therap., 315:136-143, 2005. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15958719)
Hartz, A.M.S., Bauer, B., Baehr, C.H., Miller D.S., and Fricker, G. Drug delivery across the blood-brain barrier. Current Nanoscience, 1:203-209, 2005.
Zhang, W., Wang, T., Pei, Z., Miller, D.S., Wu, X., Block, M.L., Wilson, B., Zhang, W., Zhou, Y., Hong, J.-S., and Zhang, J. Aggregated α-Synuclein activates microglia: a process leading to disease progression in Parkinson’s disease. FASEB J., 19:533-42, 2005. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15791003)
Wang T, Pei Z, Zhang W, Liu B, Langenbach R, Lee C, Wilson B, Reece JM, Miller DS, Hong JS. MPP+-induced COX-2 activation and subsequent dopaminergic neurodegeneration. FASEB J., 19:1134-6, 2005. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15845609)
Hartz, A.M.S., Bauer, B., Fricker, G., and Miller D.S. Rapid modulation of p-glycoprotein-mediated transport at the blood-brain barrier by TNF-α and LPS. Mol. Pharm., 69:462-470, 2006. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16278373)
Dallas, S., Miller, D.S., and Bendayan, R. Multidrug resistance-associated proteins (MRPs): Expression and function in the central nervous system. Pharmacol. Rev., 58:140-161, 2006. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16714484)
Wang T, Zhang W, Pei Z, Block M, Wilson B, Reece JM, Miller DS, Hong JS. Reactive microgliosis participates in MPP+-induced dopaminergic neurodegeneration: role of 67 kDa laminin receptor. FASEB J.20:906-15, 2006. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16675848)
Bauer B, Yang X, Hartz AM, Olson ER, Zhao R, Kalvass JC, Pollack GM, Miller DS.. In vivo activation of human PXR tightens the blood-brain barrier to methadone through P-glycoprotein upregulation. Mol Pharm, 70:1212-1219, 2006. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16837625)
Hartz, A.M.S., Bauer, B., Fricker, G., and Miller D.S. Rapid modulation of p-glycoprotein-mediated transport at the blood-brain barrier by TNF-α and LPS. Mol. Pharm., 69:462-470, 2006. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16278373)
Bauer, B., Hartz, A.M.S., and Miller D.S. TNF-α and endothelin-1 increase P-glycoprotein expression and transport activity at the blood-brain barrier. Mol. Pharm., 71:667-75, 2001, 2007. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17132686)
Hartz, A.M.S., Bauer, B., Block, M.L., Hong, J.-S., Miller, D.S. Diesel exhaust particles induce oxidative stress, pro-inflammatory signaling, and P-glycoprotein upregulation at the blood-brain barrier. FASEB J., 22:2723-2733, 2008. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18474546)
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