Laboratory for Integrative Neuroscience
David Lovinger
Education
B.A. University of Arizona, 1981
Ph.D. Northwestern University, 1987
Research Interests
Interactions of intoxicating and general anesthetic agents with ligand-gated ion channels in mammalian neurons, and the contributions of such interactions to intoxication and anesthesia.
Characterization of the biophysical properties of 5-HT3 receptor-linked ion channels.
Synaptic transmission, modulation and plasticity in the striatum.
Selected Publications
Gerdeman, G. and Lovinger, D.M. Postsynaptic endocannabinoid release is necessary for long-term depression in the striatum. Nature Neuroscience 2002;5:446-451.
Lovinger DM. NMDA receptors lose their inhibitions. Nat Neurosci 2002;5:614-6. 
Partridge, J. and Lovinger, D.M. Nicotinic Acetylcholine Receptors Interact with Dopamine in Induction of Striatal Long-Term Depression. J Neurosci 2002;22:2541-2549.
Stocca, G. and Lovinger, D.M. PKC and adenosine modulation of presynaptic calcium transients at hippocampal synapses Hippocampus 2002, in press.
Woo, N.-S., Delpire, E., Lue, J., England, R., McClellan, R., Dufour, S., Deutch, A.Y. and Lovinger, D.M. Hyper-excitability and epilepsy associated with disruption of the mouse neuronal-specific K-Cl cotransporter gene. Hippocampus 2002;12:258-268.
Lovinger DM, Sung KW, Zhou Q. Ethanol and trichloroethanol alter gating of 5-HT3 receptor-channels in NCB-20 neuroblastoma cells. Neuropharmacology 2000;39:561-70. pdf
Lovinger DM. 5-HT3 receptors and the neural actions of alcohols: an increasingly exciting topic. Neurochem Int 1999;35:125-30. Review. pdf
Mailing Address
Chief, Laboratory of Integrative Neuroscience
National Institute on Alcohol Abuse and Alcoholism
Room 158H Park 5 Building
12420 PARKLAWN DRIVE
ROCKVILLE, MD 20852