2008 Application CatalogProgram DescriptionClinical Cancer Prevention ResearchApplications of cancer prevention strategies require a direct link to individuals and human populations. Clearly, collaborations between clinical and pre-clinical scientists will bolster the understanding of mechanisms of carcinogenesis and aid in identifying targets for prevention. However, despite creative animal and laboratory models, humans with their innate and acquired complexity are essential for intervention studies. Also deeply intertwined within the broad field of clinical prevention, and meriting further attention, are crucial issues relating to drug development processes, protection of human subjects, and ethical implications associated with prevention research. Clinical cancer prevention research training, with its focus on translational prevention research, is one of the newest additions to the CPFP. Clinicians have the opportunity to participate in multidisciplinary research, the hallmark of the CPFP, in order to help bridge the gap between clinical and pre-clinical cancer prevention science. This training incorporates unique features while maintaining the identical structure of the parent program, including eligibility, stipend, benefits, application procedures, and evaluations. Background and Rationale. Clinical research is fundamental to the practice of cancer prevention. Over the past decades, with advances in the basic sciences, innovations in bioengineering, and findings from epidemiologic studies, the multidisciplinary field of cancer prevention has flourished. Through clinical research, the application of these discoveries has led to the identification of effective chemopreventive agents, novel early detection technologies, and recognition of individuals at high risk of developing cancer. Additionally, clinical intervention trials, as exemplified in the nutritional and behavioral sciences, have yielded successful cancer prevention strategies. The design, implementation, analysis, and interpretation of clinical prevention studies is a relatively new research area for which few clinicians are adequately trained. The opportunity now exists within the CPFP for postdoctoral clinicians, including physicians, nurses, psychologists, and pharmacists, to combine formal training in clinical research methodology with their clinical acumen and interest in cancer prevention. Brief Program Description. The program provides:
Research Opportunities. General categories of research topics include:
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