Archives and Modern Manuscripts Program, History of Medicine Division
Processed by Kent Woynowski; Processing Completed January 2003; Encoded by Kent Woynowski


Descriptive Summary
	Collection Number:	MS C 526
	Creator:	Fredrickson, Donald S.
	Title:	Donald S. Fredrickson Papers
	Dates:	1910-2002 (bulk 1960-1999)
	Quantity:	55.4 linear feet (53 boxes)
	Abstract:	Donald Sharp Fredrickson (1924-2002) was an American physiologist and science administrator who made contributions to American medicine over the course of four decades, first as a laboratory scientist, then as a leader of several prominent medical research institutions. As director of the National Institutes of Health from 1976 to 1981, Fredrickson mediated between scientists and the federal government during contentious, far-ranging debates over the direction of medical research policy, research funding, and the dangers of genetic engineering. The collection consists of a wide range of materials related to Fredrickson's scientific and administrative careers

Biographical Note

Donald S. Fredrickson (1924-2002), a physiologist and science administrator, made signal contributions to American medicine over the course of four decades, first as a laboratory scientist, then as a leader of several prominent medical research institutions. Fredrickson's studies of the connection between lipid metabolism (the processing of lipids, chief among them fats and cholesterol, in the body) and heart disease made him one of the most widely cited physiologists of the 1960s and 1970s. His system of classifying disorders in lipid metabolism was adopted by the World Health Organization as an international standard for identifying increased risks of coronary artery disease, heart attack, and stroke linked to the consumption of fats and cholesterol. He also discovered two diseases, cholesterol ester storage disease and Tangier Disease, caused by genetic disorders in the storage of cholesterol in the body. As director of the National Institutes of Health (NIH), the world's foremost biomedical research facility, Fredrickson mediated between scientists and the federal government during contentious, far-ranging debates over the direction of medical research policy, research funding, and the potential dangers of genetic engineering that took place in the second half of the 1970s.

Donald Sharp Fredrickson was born in Cañon City, Colorado, on August 8, 1924. During World War II he enlisted in the army reserves at the University of Colorado before transferring to the Army Specialized Training Program in engineering at the University of Michigan, a subject for which military tests had indicated a special aptitude. After another aptitude test and with the end of the war in sight, Fredrickson settled on medicine as his true calling. He received his bachelor's degree in 1946 and his medical degree in 1949, both from the University of Michigan. He was certified by the American Board of Internal Medicine in 1957.

While touring Europe by bicycle, Fredrickson met Henriette Priscilla Dorothea Eekhof, a law student at the University of Leyden. They married in her hometown of The Hague in 1950. After one year of separation, Henriette joined her husband in the United States. During the 1950s, she supported the junior scientist and their two sons through an import company for Dutch cigars she founded in their home.

Fredrickson conducted postgraduate research at Harvard University Medical School and Massachusetts General Hospital before arriving at the National Institutes of Health in Bethesda, Maryland, in 1953. He was one of ten young physicians chosen by NIH Director James Shannon as clinical associates in the National Heart Institute and assigned to the Institute's research laboratories in the newly opened NIH Clinical Center. From an early stage in his professional career, Fredrickson sought to integrate laboratory research with clinical practice, and to place science in the service of treating disease.

After a research career in laboratories devoted to cellular metabolism, physiology, and molecular diseases, he became director of the National Heart Institute (NHI), now known as the National Heart, Lung and Blood Institute (NHLBI), in 1966, a position he held until 1968. During his term as director the first heart transplant in man was performed by South African heart surgeon Dr. Christiaan Barnard, with whom Fredrickson arranged a meeting on December 18, 1967, at Chicago's O'Hare airport. The historic meeting was attended by prominent heart surgeons in the United States who soon after replicated Barnard's feat. Fredrickson remained at the National Heart Institute as Director of Intramural Research until 1974.

In late spring of 1974, Dr. Fredrickson left the NIH to become the second President of the Institute of Medicine, a Washington, D.C. health care and medical research policy think tank under the auspices of the National Academy of Sciences. He recalled that he was attracted to his new position because "there was a rich mixture of the dialects and ethics operative in the world outside the laboratory walls" that offered "an unparalleled view of the complex field of human health." During his brief tenure at IOM he proved an effective fundraiser, a new role for an official used to administering, not soliciting, research funds.

Almost from the moment Dr. Fredrickson joined the Institute of Medicine, he was drawn once again into the administrative politics of NIH. The directorship of NIH had become vacant for the second time in as many years. Fredrickson received phone calls from federal officials indicating dissension in the upper ranks of NIH, and asking Fredrickson to step into the void of leadership by becoming NIH director. On April 19, 1975, Fredrickson returned to Bethesda as director of NIH. In a conversation with Philip Handler, the President of the National Academy of Sciences, Fredrickson justified his decision by stating that leading NIH was "not a job; it's a cause."

Over the next six years, Fredrickson's administrative and political skills were frequently tested during the most turbulent period in the history of the NIH. Immediately he was thrown into the growing controversy over the environmental hazards and the ethics of recombinant DNA research, cutting-edge genetic experimentation that, critics warned, could produce new and untreatable pathogens and presented an unwarranted human manipulation of the natural order. During the economic and budget crises of the late 1970s, the U.S. Congress considered reducing government funding on which NIH and, through its extramural grant program, most biomedical research in the United States depended. Fredrickson had to counter arguments from members of Congress who sought to curtail NIH funding by arguing that basic research sponsored by NIH did not yield clinical applications and therapies rapidly enough to benefit patients. Not least, Fredrickson had to adjust to the changing priorities of the three U.S. Presidents and five Secretaries of Health, Education, and Welfare (since 1980, Health and Human Services) under whom he served.

Fredrickson's main successes as NIH director lay in devising guidelines for recombinant DNA research that preserved the freedom of scientific inquiry while allaying public fears of genetic manipulation; stabilizing NIH funding at a time of retrenchment; and fostering consensus among clinical and scientific researchers at NIH, groups that often found themselves at odds in their research objectives and struggle for funding. With these controversies alleviated, Fredrickson stepped down as director of NIH in June of 1981.

After two years as Scholar-in-Residence at the National Academy of Sciences, Fredrickson first became vice president, then president, CEO and trustee of the Howard Hughes Medical Institute (HHMI), founded in 1953 by the aviator and industrialist. Fredrickson oversaw the sale of the Institute's sole asset, the Hughes Aircraft Company, for six billion dollars, as well as the Institute's subsequent expansion into the largest source of philanthropic support for biomedical research in the United States, dispensing research grants and supporting laboratories in hospitals, academic institutions, and research organizations. Moreover, Fredrickson organized the relocation of the Institute from Coconut Grove, Florida, to Chevy Chase, Maryland, in close proximity to NIH. He resigned all of his positions at HHMI in 1987 under allegations of financial irregularities, allegations he strongly denied and which were never proved.

From 1987 until his death, Fredrickson was Scholar-in-Residence at the National Library of Medicine, as well as a consultant on medical research and health care issues in the United States and abroad as President of D. S. Fredrickson Associates. Drawing on his early medical training, he became medical adviser to King Hassan II of Morocco in 1975, a service for which he was elected a member of the Academy of the Kingdom of Morocco in 1991.

Dr. Fredrickson died at his home in Bethesda on June 7, 2002.

Brief Chronology


	Date	Event
	1924	Born in Cañon City, Colorado (August 8)
	1943-1946	Engineering student in the Army Specialized Training Program
	1946; 1949	Receives B.S. and M.D. degrees from the University of Michigan
	1949-52	Postdoctoral training in internal medicine at Peter Bent Brigham Hospital in Boston
	1950	Marries Dutch law student Henrietta Priscilla Dorothea Eekhof in The Hague, Netherlands
	1950-1951	James Jackson Cabot Research Fellow in Medicine, Harvard Medical School
	1952-1953	Research fellow in medicine at the Massachusetts General Hospital in Boston
	1953-1955	Clinical Associate, National Heart Institute, National Institutes of Health (NIH) in Bethesda, Maryland; investigates lipid transport in the blood
	1955-1961	Member of the senior research staff in the Laboratory of Cellular Metabolism, National Heart Institute
	1957	Certified by the American Board of Internal Medicine
	1960	First to describe and name Tangier disease, an abnormality in the storage of cholesterol in the body
	1960	Publishes standard textbook, The Metabolic Basis of Inherited Disease, with John B. Stanbury and James B. Wyngaarden
	1961-66	Clinical Director, National Heart Institute
	1962-66	Head of the Section on Molecular Diseases in the Laboratory of Metabolism, National Heart Institute
	1966-68	Director, National Heart Institute
	1967	New England Journal of Medicine publishes a five-part review of Fredrickson's work on abnormalities in lipid metabolism
	1968-74	Scientific director, National Heart Institute
	1973	Participants at the Gordon Conference on Nucleic Acids in New Hampshire call on their fellow scientists to voluntarily suspend certain experiments with recombinant DNA
	1974-75	President of the Institute of Medicine of the National Academy of Sciences
	1975-81	Director, National Institutes of Health
	1975	Over 140 prominent molecular biologists and geneticists attending the Asilomar conference on the dangers of genetically reengineered microorganisms propose a voluntary moratorium on recombinant DNA research until its scientific and ethical implications could be explored
	1975-78	Chairman, Recombinant DNA Advisory Committee (RAC)
	1975-81	Chairman, Interagency Committee on Recombinant DNA Research
	1976	Releases NIH Guidelines for Research Involving Recombinant DNA Molecules (June 23)
	1976	Issues a draft Environmental Impact Statement for recombinant DNA experiments (September); a final statement is issued October 1977
	1977	Initiates NIH Consensus Development Conferences to bridge scientific and professional differences among NIH personnel
	1978	RAC expanded to include non-scientists, among them the new RAC chairman
	1978	Chairs National Conference on Health Research Principles, held at NIH
	1978	Establishes the Office of Medical Applications of Research at NIH
	1979	Revised recombinant DNA guidelines take effect (January 2), easing containment requirements particularly for experiments involving Escherichia coli strain K-12 as a host-vector system
	1979	In a time of federal budget shortfalls, Fredrickson secures funding for a minimum of 5,000 new NIH research grants
	1981-83	Scholar-in-Residence, National Academy of Sciences
	1983-87	Vice President, then President and CEO of the Howard Hughes Medical Institute, Chevy Chase, Maryland
	1987-2002	Scholar at the National Library of Medicine, Bethesda
	1987-2002	President, D.S. Fredrickson Associates, a health and science policy consulting firm
	2002	Dies at his home in Bethesda (June 7)

Awards and Prizes

American College of Physicians Award

American College of Cardiology Distinguished Service Award

American College of Cardiology Gold Medal Award

American Heart Association Award of Merit

American Society for Clinical Nutrition McCollum Award

Arthur M. Sackler Foundation Award for Service to Science

Commandeur de Ouissam Alaouite

Department of Health and Human Services Distinguished Public Service Award

Fondazione Lorenzini Medal (Milan)

Gairdner Foundation Award

Intrascience Award

James F. Mitchell International Award for Heart and Vascular Research

Jimenez Diaz Award (Madrid)

La Madonnina Prize for Science (Milan)

Lifetime Achievement Award, Sandoz Research Institute

Modern Medicine Distinguished Achievement Award

National Cholesterol Award for Public Health Scientific Achievement

New York Academy of Science Sarah L. Poiley Award

Phi Rho Sigma Irving Cutter Medal

Purkinje Medal (Prague)

Society of Research Administrators Distinguish Contribution to Research Administration Award

Editorial Appointments

American Journal of Medicine, Editorial Board

American Physiology Society, Chairman, Publications Committee

Circulation Research, Editorial Board

Health Affairs, Member of the Advisory Board

Issues in Science and Technology, Member of the Advisory Board

Journal of Atherosclerosis, Editorial Board

Journal of Clinical Investigation, Editorial/Advisory Boards

Journal of Lipid Research, Advisory Board

Physiology in Medicine, Advisory Board

Honorary Degrees

George Washington University

Georgetown University

Karolinska Institutet

Medical University of South Carolina

Mount Sinai School of Medicine

University of Medicine and Dentistry of New Jersey

University of Michigan

University of North Carolina

University of Rochester

Yeshiva University

Lectureships

American Academy of Dermatology, Marcus R. Caro Memorial Lecture

American College of Cardiology, Seventeenth Annual Convocation Lecture

American Dermatological Association, The Carl Herzog Guest Lecture

American Swiss Foundation for Scientific Exchange University Lectures (Basel, Bern, Lausanne, Geneva, Zurich)

Association of American Medical Colleges, Symposium Speaker

Association of American Physicians, The Distinguished Lecture

Columbia University Conference Science, the Endless Frontier, Speaker

Cornell-N.Y. Hospital Policy Conference, Speaker

Deutsch Gesellschaft für Klinische Chemie (Bonn), Plenary Lecture

Institute of Medicine, Twentieth Annual Meeting, Chairman

International Atherosclerosis Society, First Donald S. Fredrickson Lecture on Lipoprotein Research

National Institutes of Health Centennial, Plenary Lecture

National Library of Medicine, Lister Hill Center, Lecture

National Research Council Facilities, Keynote Address, Dedication

Royal Academy of Morocco, Casablanca, Speaker

Royal Academy of Morocco, Paris, Speaker

Royal Academy of Morocco, Rabat, Speaker

Stanford University, John Kent Lewis Memorial Lecture

Tokyo University, Lecture

University of Alabama Birmingham, The Reynolds Lecture

University of Pennsylvania, Third Bernard H. Pastor Memorial Lecture

Memberships

Alpha Omega Alpha

American Academy of Arts and Sciences

American Association for the Advancement of Science, Fellow

American College of Cardiology, Fellow

American College of Physicians, Fellow

American Federation for Clinical Research

American Heart Association, Council for the Study of Arteriosclerosis

American Philosophical Society

American Physiological Society

American Society for Clinical Investigation

American Society of Human Genetics

Association of American Physicians

British Cardiac Society, Corresponding Member

College of Medicine of Valencia (Honorary)

Cosmos Club

Deutsche Gesellschaft für Innere Medizine, Corresponding Member

Harvey Society (Honorary)

Institute of Medicine, Academy of Sciences

International Society of Cardiology

Medical Society of Sweden (Honorary)

National Academy of Sciences

Peripatetic Club

Phi Beta Kappa

Phi Kappa Phi

Royal Academy of the Kingdom of Morocco

Royal College of Physicians, London, Fellow

Society of Pediatric Research

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Collection Summary

Correspondence, photographs, diaries, research materials, reports, writings, drafts, and audiovisual materials (1910-2002; 55.4 linear feet) document the semi-official portion of Donald S. Fredrickson's professional career as a leading biomedical administrator and policy maker. Beginning with his clinical laboratory career at the National Heart Institute, Fredrickson spent over 28 years at NIH, culminating in 1975-1981 when he was Institute Director. During the course of his career, Fredrickson became world-renowned for his dynamic leadership qualities and creative vision about the future directions of biomedical research in the U.S. and NIH's role in that future.

The collection consists largely of records of Fredrickson's activities (travel, talks, etc.) outside the institutions with which he was associated and of subject files he used primarily for his historical researches later in his career. The collection includes a significant amount of correspondence, as well as a large selection of biographical materials, including diaries, scrapbooks, and reminiscences.

Fredrickson began his career as a clinical associate at the National Heart Institute (NHI) in 1953, where he discovered two genetic disorders of the storage of cholesterol in the body: cholesterol ester storage disease and Tangier disease. Aside from articles and speeches, there is very little primary source material (e.g., lab notebooks) documenting his clinical research career at NHI. As Director of NHI, he organized a Conference on Cardiac Transplantation in response to the first human heart transplant, performed by South African heart surgeon Dr. Christiaan Barnard. The collection contains a fair amount of materials on this conference, including memos, schedules, and photographs in Series VIII: Professional Activities, National Heart Institute sub-series.

In 1975, Fredrickson was appointed Director of the National Institutes of Health. As Director, Fredrickson led NIH in developing guidelines for recombinant DNA research, and stabilized NIH funding for extramural grants in the face of Congressional budget cuts. Important documentary materials from this period of Fredrickson's career include research materials he prepared for his book The Recombinant DNA Controversy: A Memoir, and the materials of Series V: Director, NIH, Authorization sub-series, which include reprints, correspondence, memos, notes, etc. relating to grant funding at NIH.

Following his career at NIH, Fredrickson became President and CEO of the Howard Hughes Medical Institute. Series VIII: Professional Activities, Howard Hughes Medical Institute sub-series contains diaries, correspondence, and newspaper clippings relating to Fredrickson's HHMI presidency.

After a long career of administration, Fredrickson turned to historical research, as a Scholar-in-Residence with the U.S. National Library of Medicine. The materials of Series IX: Clinical Center are the product of that research and provide valuable insight into the history of the NIH Clinical Center. They include photographs, notes, correspondence, and interviews.

The files of Series IX: Clinical Center, Series IV: Recombinant DNA Materials and the Authorization sub-series of Series V: Director, National Institutes of Health are peculiar in their nature and arrangement. These materials tend not to be original documents, but rather photocopies of the originals, along with additional comments by Fredrickson, which he created on his computer and printed out. The digital files are no longer available, but Fredrickson preserved their arrangement in his paper filing system, noting the titles of the original hard drive folder and sub-folder on each item. In order to preserve the original organization, sub-series titles replicate the computer hard drive's top-level file naming convention. Fredrickson discusses his filing system arrangement for these series in an interview titled "Fredrickson on the Recombinant DNA Controversy," located in Series XI: Audio-Visual Materials, Audio Materials sub-series.

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Restrictions

Portions of the collection are restricted. Contact the Reference Staff for information regarding access. For online customer service, please visit http://www.nlm.nih.gov/contacts/custserv-email.html.

Copyright

Copyright was transferred to the public domain. Contact the Reference Staff for details regarding rights. For online customer service, please visit http://www.nlm.nih.gov/contacts/custserv-email.html.

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Index Terms
	These terms are indexed in the National Library of Medicine's online catalog LocatorPlus. Researchers wishing to find related materials should search the catalog using these terms.
	MeSH Subjects
		Biomedical Research -- ethics
		DNA, Recombinant
		Health Policy
		Public Health Administration
	Corporate Names
		National Institutes of Health (U.S.)

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Administrative Information

Alternate Forms Available

Portions of the Collection have been digitized and are available at: http://profiles.nlm.nih.gov

Preferred Citation

Fredrickson, Donald S. Donald S. Fredrickson Papers. 1910-2002 (bulk 1960-1999). Located in: Modern Manuscripts Collection, History of Medicine Division, National Library of Medicine, Bethesda, MD; MS C 526.

Provenance

Gift of Donald S. Fredrickson, 2001. Accession #2001-75.

Processing Information

Fredrickson was the subject of the first prototype website of Profiles in Science, the U.S. National Library of Medicine's Digital Manuscripts Program's digital archive and exhibition of the papers of key figures in the fields of science and health. Fredrickson was very active in the creation of this digital archive, rearranging many of his papers, adding comments and annotations to specific documents, and collecting files into new series and sub-series, particularly in Series I: Personal and Biographical and Series X: Photographic Materials. As a result, it is difficult to ascertain the "original" order of the documents in the collection.

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Series Descriptions



Series I: Personal and Biographical, 1914-2002 (bulk 1960-1990)
	The Personal and Biographical Series contains materials related to the personal life of Donald S. Fredrickson. This series consists of seven sub-series covering: resumes, Curriculum Vitae and biographies; diaries; scrapbooks; awards; personal reminiscences; memorabilia; and newspaper clippings about Fredrickson.




	The series contains a great deal of information about Fredrickson's childhood and early years in the form of a scrapbook maintained by his mother. However, his college years and residency in Boston are under-represented. Throughout much of his later professional career, Fredrickson kept detailed diaries, which reveal his personal thoughts and motivations.




	Additional biographical information can be found in the Audio-Visual Materials Series, Audio Materials sub-series in the form of an interview with Fredrickson conducted by archivists from NLM.




	The Resumes, CVs, and Biographies sub-series contains information on Fredrickson's personal life and professional career. Created from loose materials found in the collection, this series is semi-artificial in nature. The majority of materials in this sub-series are files collected by NLM's Digital Manuscripts Program and Fredrickson for the purpose of creating the prototype website for Profiles in Science.




Box	Folder
		Resumes, Curriculum Vitae, and Biographies, 1965-2002

1	1		Modern Medicine Biography, 1965 Dec 20
1	2		Biographical Information, 1965-1981
1	3		DSF Publicity, 1967
1	4		[Area Knowledge Report], [ca. 1970]
1	5		[Various Chronologies, Publication Lists, and CVs], 1975-1997
1	6		"America's Research Baron", 1977
1	7		Some Data for Future Biography, 1980-1989
1	8		Executive Personnel Financial Disclosure Report, 1981
1	9		Who's Who in the East, 1981
1	10		FBI and IRS Background Check, 1982
1	11		DSF's Parents' Obituaries, 1982, 1984
1	12		"How Washington Has Changed" [Washingtonian Biography of DSF], 1985 Oct
1	13		[IOM Biographical Essay], 1990
1	14		[Autobiography], 1992
1	15		Curriculum Vitae, 1996 Mar
1	16		Biographical Sketch for 50th Anniversary Celebration, 1996 May
1	17		A Short Biography of Dr. Fredrickson, 1997 Oct 29
1	18		"Fredrickson Reflects on Politics of Recombinant DNA Research", 2002 Jan 22
		Diaries
				The Diaries sub-series contains the diaries and journals that Fredrickson kept throughout most of his career. In addition to the journal entries, correspondence, newspaper clippings, magazine articles, and notes are present in the diaries. The diaries include personal information, as well as information on Fredrickson's professional activities and interests.
				The "Green Diaries" date from 1972 to 1981 and deal primarily with Fredrickson's career at the National Institutes of Health, which included his tenures at the National Heart, Lung, and Blood Institute (NHLBI), and as NIH Director. Volume II and Volumes V through X are missing from the collection. It is presumed that Fredrickson did not donate the volumes and that they remain with his family. Much of the information contained in these volumes is available in the collection, but the information is scattered throughout the different series. Before donating his papers, Fredrickson reorganized them, inserting comments throughout the collection. Many of these comments come in the form of annotated diary entries copied from the "Green Diaries."
				The "Black Diaries" date from 1983 to 1996. Included at the end of the last volume is a list of Fredrickson's diary entries found only on diskette. The diskettes are not included in the collection and their whereabouts are unknown.
1	19		Diary II - 50s through 70s, 1967-1976
			Green Diary

1	20			Volume I, 1972 Jan - 1979 Feb
1	20a			Volume I [Extraneous Materials], 1972 Jan - 1979 Feb
1	21			Volumes III/IV, 1980 Jun - 1980 May
1	22			Volume XI, Excerpts, 1981
			Black Diary

1	23-42			Volume 1-9, 1983-1987
2	1-22			Volume 9 (cont'd.)-19, 1987-1996
2	23			Record of Diary Entries on Diskettes "Diary 1, 2, 3, 4", 1987-1997
2	24			Diskette Entries, 1987-1996
2	25			Scan, 1984-2000
2	26		DSF Diary (see also Black Diaries), 1989-1997
		Scrapbooks, 1914-1990

OS1	1		Notes, 1990 May 19
OS1	2-29		Childhood Scrapbook, [1914-1940s]
OS2			Childhood Scrapbook (cont'd.)
2	27-36		Brown Scrapbook, [1958-1975]
3	1-5		Brown Scrapbook (cont'd.), [1958-1975]
3	6-45		Clippings Scrapbook [5 volumes], 1963-1981
OS4	1		Resignation Scrapbook, [1974]
3	46		NIH Alumni Reunion Scrapbook, 1975
3	47-48		Letters Scrapbook, 1979-1981
3	49		Vincent T. DeVita Scrapbook, 1980
2	27		[Various unidentified scrapbook pages], [ca. 1940-1950]
2	28		[Unidentified scrapbook pages], 1949-1972
		Awards, 1951-1992

3	50		[Admission to the] Medical and Metaphysical Society, 1951
3	51		Stouffer Prize, 1967-1969
3	52		27o Congresso Brasileiro de Cardiologia [27th Brazilian Congress on Cardiology], 1971
3	53		Modern Medicine Award for Distinguished Acheivement, 1971 Jan 11
3	54		American Academy of Arts and Sciences, 1975
3	55		Karolinska Institutet, 1977
3	56		Gairdener Award, 1978
3	57		Irving S. Cutter Medal, Phi Sigma Rho, 1978 Feb
3	58		University of Athens, Honorary Degree, 1980-1981
OS3	1		Medical University of South Carolina Honorary Degree, 1985 May 17
OS3	2		Sackler Award, 1986
3	59		Fuiggi International Award, 1987
3	60		Who's Who in America, 1991
3	61		Sandoz Publicity, 1991-1992
		Reminiscences, 1963-1997

3	62-63		DSF Calendar, 1981-1982
3	64		DSF - Personal, 1976-1989
4	1		Congrel [Congresional Relations], 1978
4	2		Aagenl [General], 1990-1992
4	3		DSF Papers Info, 1981-1990
4	4		Personal - NIH 1975, 1968-1989
4	5		Personal - NIH 1976, 1975-1976
4	6		Citation, 1977-1991
4	7		Obituaries, 1977-1998
4	8		Personalities, 1969-1999
4	9		Docs in NLM, 1989
4	10		Farewell Lunch [Anderson, French], 1992
4	11		NLM and Elsevier [?], 1982
4	12		DSF Papers 1976, 1976, 1990
4	13		Personal - NIH 1977, 1977
4	14-17		DSF Papers 1977, 1977-1980
4	18		Testimony on National Arthritis Institute, Senate Committee on Labor, 1982 Jul 20
4	19		Sundry Memberships [EPCOT Center], 1981
4	20		DSF to be processed, 1965-1971
4	21		C, 1963-1990
4	22		"Grist for the Mill", 1968-1974
4	23		Trustees, 1986
4	24		Brigham and Women's Hospital Medical Staff and Alumni Directory, 1992
4	25		[Cañon City History], 1992
4	26		[64th Birthday], 1988
4	27		First Heart Transplant in Man, 1997 Apr 26
		Memorabilia, 1944-1981
4	28		University of Michigan Honors Convocation and Commencement, 1944, 1946, 1949
Map Drawer 7			[Tangier Disease Collage], [1960s]
OS3	3		[Tangier Disease Collage Viewing Copy], [1960s]
OS3	4		[Signed Photograph of President Lyndon Johnson's Visit to NIH], 1965 Aug 9
OS3	5		[Signed Photograph of President Lyndon Johnson's Visit to NIH], 1967
4	29		Memorabilia, 1967-1981
OS3	6		[Franco Conti, Cesare Sirtori, and Oreste Mantero], 1975
4	30		NIH Director Badge, 1975
4	31		Passports, 1976-1981
4	32		NIH Challenge Relay, 1976
4	33		University of Michigan 1977 Winter Commencement, 1977
OS3	7		[Autographed portrait of Ted Kennedy and Paul Rogers], 1977
OS3	8		[Autographed photograph of Jimmy Carter], 1980 May
4	34		Steve Hall Drawings, [n.d.]
		Newspaper Clippings, 1957-1981

4	35		New York Times - "The Visible Hand", [n.d.]
4	36		Pueblo (Colo.) Star-Journal - "Drug to Curb Cholesterol", 1957 Mar 3
4	37		Scope Weekly - "Experts Weigh Effects of Dietary Fats", 1957 Mar 27
4	38		Virginia Pilot - "Tonsils May Cure Hearts", [ca.1960s]
4	39		Washington Post - "Ted's Tonsils Offer Heart Disease Cure", [ca.1960s]
4	40		InternistObserver - "Blood Lipids", 1963 Mar-Apr
4	41		Oklahoman - "Additional Public Support Urged at Medical Institute", 1963 May 5
4	42		Evening Bulletin, Philadelphia - "Specialists Doubt Cholesterol's Importance in Heart Disease", 1967 Feb 23
4	43		Modern Medicine - "Defining High Cholesterol", 1968 Oct 7
4	44		Clinical Laboratory Forum - "Classical Laboratory Technique Now Applicable to Study of Lipidemia", 1969 Apr
4	45		Otago Daily Times, New Zealand - "Women Less Susceptible to Heart Attack 'Plague'", 1971 Sep 23
4	46		Southland Times, New Zealand - "Premature Heart Attacks on Increase", 1971 Sep 24
4	47		Christ Church Star, New Zealand - [Television listing], 1971 Sep 25
4	48		The Press, New Zealand - "N.Z. Diets Questioned", 1971 Sep 26
4	49		Christchurch Star - "Killer 'We Must Arrest at Once'", 1971 Sep 27
4	50		The Press, New Zealand - "Heart Week", 1971 Sep 27
4	51		The Press, New Zealand - "Smoking a Factor in Heart Attacks", 1971 Sep 28
4	52		Honolulu Star Bulletin - "The Boss? He's at his Summer Home", 1971 Sep 29
4	53		New Zealand Herald - "Lessons Which Must Be Taken to Heart", 1971 Oct 1
4	54		New Zealand Herald - "Diet Link with Heart Trouble", 1971 Oct 2
4	55		Canberra Times, Australia - "One-in-Four Potential Heart Attack Victim", 1971 Oct 5
4	56		West Australian - "Early Checks for Heart Risks Urged", 1971 Oct 9
4	57		The Rising Nepal, 1971 Oct 11
4	58		The Rising Nepal, 1971 Oct 12
4	59		Latest Advancement in Health Research, 1972
4	60		Washington Post - "Shift to Coal Seen Shortening Lives", 1974 Feb 16
4	61		Drug Research Reports - "NIH's Fears Become Real", 1974 Dec 11
4	62		Washington Post - "NIH and the Real World", 1974 Dec 27
4	63		Washington Report on Medicine and Health - "Cooper and Fredrickson Nominations Sent to Senate by Ford", 1975 Apr 28
4	64		Washington Post - "Worldviews", 1975 May 11
4	65		Washington Post for Tangier File, 1975 Jun 2
4	66		Philadelphia Inquirer - "Cancer Research Unit Opens", 1975 Jun 12
4	67		Washington Post - "A Scientific Breakthrough", 1976 Jul 2
4	68		York, PA Newspaper - "Legion Disease: Man-made Virus?", 1976 Aug
4	69		The Nation's Health [APHA] - [June Christmas Awarded Domestic Award], 1976 Nov
4	70		Washington Star - "A Black Quota in Research?", 1976 Nov 1
4	71		New York Times - "American Scientists Report Important Benefits from Joint Medical Research with the Russians", 1976 Nov 23
4	72		Observer, Great Britain - "The Babies That Need Not Die", 1976 Dec 12
4	73		Washington Report on Medicine and Health - "Harris-NIH Dispute Continues", 1980 May 12
4	74		Washington Star - "NIH Director Fredrickson Announces He Will Resign", 1981 Jun 19
4	75		New York Times - "Director of the National Institutes of Health Quits Post Citing Personal Reasons", 1981 Jun 20
4	76		Washington Post - "NIH Director Fredrickson Resigns, Citing 'Personal Reasons'", 1981 Jun 20
4	77		Washington Star - "Fredrickson Resigns as Director NIH", 1981 Jun 20
4	78		Nature - "Fredrickson Quits Without Warning", 1981 Jun 25
4	79		The NIH Record, 1965 Feb 9 - 1991 Apr 2

Return to the Table of Contents



Series II: Correspondence, 1948-1998
	The Correspondence Series consists of Fredrickson's professional and personal correspondence with individuals and organizations, discussing a wide variety of subjects, and covering all aspects of Fredrickson's career. The series is divided into five sub-series, mostly based on Fredrickson's own organizational scheme: professional correspondence, personal correspondence, resignation letters, daily letter files, and writing engagements.




	A good deal of personal information is available in the Personal Correspondence sub-series, especially in the Fredrickson family correspondence. Researchers interested in family correspondence should also consult the Scrapbooks sub-series of Series I: Personal and Biographical, which contains a great deal of early correspondence between Fredrickson and his parents.




	The "Inquiries" folders, as labeled by Fredrickson, range from 1966-1974 and cover Fredrickson's time at the National Heart, Lung and Blood Institute (NHLBI). These files relate to requests for information or research guidance from Fredrickson, mostly concerning his experience with Tangier Disease and lipoproteins.




Box	Folder
		Professional Correspondence, 1954-1997

5	1		A - Ahr, 1956-1990
5	2		Alaupovic, Pierre, 1964-1993
5	3		Alm - And, 1962-1992
5	4		Anfinsen, Christian B., 1954
5	5		Anl - Ari, 1975-1995
5	6		Armstrong, Neil A., 1989
5	7		Aro - Asp, 1960-1996
5	8		Assmann, Gerd, 1975-1997
5	9		Att - Bay, 1958-1992
5	10		Bea - Berge, 1971-1992
5	11		Bergström, Sune, 1956-1975
5	12		Berk - Berl, 1994-1997
5	13		Bernard, Jean, 1986-1994
5	14		Bers - Blai, 1967-1997
5	15		Blankenhorn, David, 1965-1970
5	16		Blas - Bra, 1960-1992
5	17		Bre - Bu, 1958-1993
5	18		C - Cau, 1961-1995
5	19		Ce - Cri, 1961-1994
5	20		Crocker, Allen C., 1959-1966
5	21		Cu - Di, 1955-1993
5	22		Dole, Vincent P., 1959-1987
5	23		Dr - E, 1961-1995
5	24		F - Fl, 1958-1997
5	25		Ford, Gerald R., 1974-1981
5	26		Fordh - Fra, 1965-1995
5	27		Fredrickson, Donald T., 1972
5	28		Free - Gil, 1956-1994
5	29		Gin - Gord, 1956-1992
5	30		Gore, Albert, Jr., 1981
5	31		Gorl - Gott, 1957-1997
5	32		Graham, Katharine, 1966
5	33		Graham, W - Hal, 1956-1993
5	34		Hamburg, David A., 1982
5	35		Hame - Han, 1963-1989
5	36		Harden, Victoria, 1983-1997
5	37		Harlan, W. - Haw, 1959-1994
5	38		Havel, Richard, 1957-1983
5	39		Hay - Hey, 1966-1994
5	40		Hi - Hut, 1956-1994
5	41		I - J, 1961-1992
5	42		K - Ke, 1961-1993
5	43		Khachadurian, Avedis K., 1964-1971
5	44		Khar - Kis, 1961-1991
5	45		Klenk, E., 1964-1965
5	46		Kler - Kod, 1962-1992
5	47		Koop, C. Everett, 1987-1989
5	48		Kop - Kun, 1962-1992
5	49		Kuo, Peter, 1959-1982
6	1		Kuz - Lan, 1960-1995
6	2		Lasker, Mary, 1967-1988
6	3		Laudat, Philippe, 1960-1986
6	4		Le - Lindb, 1959-1993
6	5		Lindgren, Frank T., 1965-1972
6	6		Linds - Ly, 1965-1984
6	7		M - Ma, 1961-1992
6	8		Mc - Me, 1961-1989
6	9		Mi - My, 1965-1992
6	10		N, 1963-1990
6	11		O - Pac, 1962-1994
6	12-14		Page, Irving H., 1956-1991
6	15		Pal - Pel, 1962-1990
6	16		Perpich, Joseph G., 1978-1982
6	17		Perr - Pop, 1958-1991
6	18		Porter, Phil, 1990
6	19		Pot -- Pz, 1969-1989
6	20		R - Re, 1958-1994
6	21		Rh - Roc, 1962-1996
6	22		Rodbell, Martin, 1960-1994
6	23		Rog - Ru, 1974-1994
6	24		S - Schm, 1961-1995
6	25		Schnaper, Harold W., 1962-1970
6	26		Schne - Sh, 1959-1994
6	27		Si -- Sir, 1957-1997
6	28		Sjoerdsma, Albert, 1988-1989
6	29		Sk - Sp, 1956-1997
6	30		Staats, Elmer B., 1983-1987
6	31		Stamler, Jeremiah, 1964-1975
6	32		Stan - Sz, 1954-1997
6	33		T - Thom, 1959-1991
6	34		Thorn, George W., 1954-1987
6	35		Thornt - Tz, 1959-1994
6	36		W - Wh, 1960-1996
6	37		Wi - Wo, 1958-1994
7	1		Wyngaarden, James B., 1961-1996
7	2		Y - Zi, 1959-1987
7	3		Zöllner, Helmut, 1961-1972
7	4		Zu, 1973-1990
7	5-14	Inquiries, 1966-1978
		Invitations Declined, 1982
7	15		A - C
7	16		D - K
7	17		L - O
7	18		P - W
7	19	Writing Obligations, 1966-1974
		Personal Correspondence, 1948-1997

7	20		Abelson, Philip H., 1982
7	21		Allen, C. R., 1981
7	22		Altrocchi, Paul H., 1961-1962
7	23		Anderson, W. French, 1987-1997
7	24		Anlyan, William G., 1981
7	25		Arantes, E Oliveira Amalia and Eduardo, 1995
7	26		Asper, Samuel P., 1981
7	27		Beattie, Richard I., 1980
7	28		Benaissa, Mohamed, 1997
7	29		Berglund, Ragnhild, 1960
7	30		Bergstrom, Sune, 1974-1976
7	31		Berliner, Robert W., 1961-1973
7	32		Bersot, Tom, 1971-1972
7	33		Bevan, William, 1985-1993
7	34		Bilheimer, David J., 1988
8	65		Biking, 1979-1981
7	35		Blobel, Günter, 1997
7	36		Blokhin, N. H., 1980
7	37		Blomquist, Nancy L., 1981
7	38		Bloom, Max R., 1981
7	39		Bond, Enriqueta C., 1994
7	40		Bosch, Jan K., 1992
7	41		Brandt, Edward, 1981
7	42		Briner, William H., 1978
7	43		Brinkley, Joe, 1986
7	44		Brooks, David J., 1981
7	45		Brown, Sarah, 1975
7	46		Bulger, Roger J., 1975
7	47		Bunim, Miriam, 1964
7	48		Butler, Robert N., 1987-1994
7	49		Cahill, George F., [1981]-1993
7	50		Califano Jr., Joseph A., 1979
7	51		Capron, Alexander, 1981
7	52		Carter, James, 1985
7	53		Carter, Tim Lee, 1980
7	54		Charles, David, 1981
7	55		Chase, Robert O., 1994
7	56		Chase, William, 1975
7	57		Christie, George C., 1993
7	58		Cohen, Robert, 1977-1978
7	59		Cohen, Sheldon, 1978
7	60		Coleman, John S., 1974
7	61		Comroe, Julius, 1976-1981
7	62		Cooper, Theodore, 1974-1978
7	63		Corn, Milton, 1987
7	64		Corning, Mary, 1982
7	65		Cornwell, Jean, 1992
7	66		Crane, Stanley, 1987
7	67		Crawford, Bryce, Jr., 1987
7	68		Cummings, Carol, 1996
7	69		Cummings, Martin, 1975-1976
7	70		Darnell, James, 1987
7	71		Davies, Norman, 1981
7	72		Davies, William D., 1985-1988
7	73		Davis, R. B., 1990
7	74		DeRábago, Pedro, 1990
7	75		DeSanctis, Roman, 1993-1998
7	76		Determan, Helmut, 1987-1997
7	77		Dow, Michael M., 1981
7	78		Ebert, Richard V., 1967
7	79		Egeli, Bjorn, 1982
7	80		Eisenberg, Leon, 1981
7	81		Engelhorn, Victoria, [n.d.]
7	82		Engelhorn-Vechiatto, Traudl, 1992
7	83		Evens, Ronald G, 1978
7	84		Fairweather, Jane, 1997
7	85		Fennessy, Róna, 1990
7	86		Fennesy, John, 1991
7	87		Finley, Wayne H., 1991-1994
7	88		Ford, Gerald R., 1975
7	89		Fouraker, Lawrence, 1978
7	90		Fredrickson, Bryan, 1973
7	91		Fredrickson, C. Arthur and Blanche Sharp Fredrickson (parents), 1948-1975
7	92		Fredrickson, Donald S., 1959
7	93		Fredrickson, Eric, 1972-1997
7	94		Fredrickson, Henrietta P. D., 1971
7	95		Fredrickson, Robert G., 1989-1997
7	96		Fretter, William B., 1981
7	97		Gajdusek, D. Carleton, 1977-1997
7	98		Giocometti, Luigi, 1984
7	99		Glaser, Robert J., 1981
7	100		Glenner, George G., 1981
7	101		Godber, George, 1974
7	102		Goodman, Ann, 1992
7	103		Goodman, Dewitt S., 1971
7	104		Gordon, Betsy, 1985
7	105		Greene, Warner C., 1987
7	106		Gromyko, 1995
7	107		Gronvall, John A., 1981
7	108		Halbach, Detlef M., 1992-1993
7	109		Handler, Philip, 1974-1975
7	110		Hatch, Orrin G., 1982
7	111		Hassan II, King of Morocco, 1977-1995
7	112		Hegyeli, Ruth J., 1987
7	113		Hitachi, Masahito, 1978
7	114		Hobbins, Peter C., 1995
7	115		Hofmann, Alan F., 1995-1996
7	116		Hollis, Calvin V., [n.d.]
7	117		Hugenholz, Paul G., 1978
7	118		Ideh, A. E., [n.d.]
7	119		Jacobs, Robert P., 1978
7	120		Jardine, Bryan W., 1990-1996
7	121		Johnston, Mrs. Franklin N., 1971
7	122		Jolly, William P., 1994
7	123		Jones, James R., 1981
7	124		Jover, David, 1995
7	125		Kadigamar, Vee, 1996
7	126		Kalkhuis, Teunis, 1996
7	127		Kannel, William B., 1978
7	128		Karateas, Dorian, 1991
7	129		Keimowitz, Robert I., 1979
7	130		Kellner, Aaron, 1981
7	131		Killip, Thomas, 1981
7	132		King, James, 1971
7	133		Klimov, Anatoly N., 1965
7	134		Klocke, Francis J., 1968
7	135		Kowalczyk, Mercy, 1987-1990
7	136		Lambo, Tom A., 1980
7	137		Li, David K. P., 1987
7	138		Lindgren, Frank T., 1978
7	139		Lindsey, Charles, 1997
7	140		MacLean, Paul D., 1975-1977
7	141		Margolis, George, 1981
7	142		Mark Twain Society, 1973
7	143		Marland, S. D., 1978
7	144		Masprangelo, Santino, 1989
7	145		McDermott, Walsh, 1981
7	146		McDowell, James E., 1969
7	147		McLachlan, Ken J., 1992
7	148		Mernissi, Mohammed, 1978
7	149		Morehead, D. E., 1978
7	150		Moure, Richard, 1981
7	151		Muhlstock, B. J., 1991
7	152		Nature, 1982
7	153		Nemetz, Martin, 1981
7	154		Neufeld, Elizabeth, 1981
7	155		Newman, Lanny, 1981
7	156		Nienhus, Arthur, 1981
7	157		Oldham, Robert K., 1981
7	158		Olseth, Nancy and Dale, [n.d.]
7	159		Omenn, Gilbert S., 1978
7	160		Ouazzani, Wafa, 1982
7	161		Owen, William R., 1968
7	162		Page, Irving H., 1981
7	163		Paskin, Norman, 1982
7	164		Pearce, Robert A., 1981
7	165		Peeters Van Hoorenbeek, Herbert and Thèrése, [n.d.]
7	166		Pena, Ada R., 1978
7	167		Perpich, Joseph G., 1979-1981
7	168		Perry, Dan, 1981
7	169		Perry, Seymour, 1982
7	170		Petito, Frank, Jr., 1986
7	171		Pines, Maya, 1987-1988
7	172		Porter, Phillip B., 1973
7	173		Prager, Dennis J., 1981
7	174		Press, Frank, 1980-1991
7	175		Price, Don K., 1981
7	176		Project Hope, 1981-1982
7	177		Radi, A., 1982
7	178		Rall, David P., 1982
7	179		Raub, William F., 1982
7	180		Reagan, Ronald, 1989
7	181		Reich, Aurora K., 1995
7	182		Rhode, Barbara, 1988
7	183		Rice, Dorothy P., 1982
7	184		Rich, Patrick [?], 1994
8a	1		Rifkind, Richard A., 1981
8a	2		Robinson, Joseph A. and Madeleine, 1992-1997
8a	3		Roman, Aurelia, 1989-1996
8a	4		Roman, George, 1982
8a	5		Rose, Richard, 1981
8a	6		Rosenblith, Walter A., 1979-1982
8a	7		Rotem, Zeev, 1982
8a	8		Roth, Jesse, 1981-1982
8a	9		Sabatos, Chuck, 1990
8a	10		Sanders, Charles, 1981
8a	11		Sarrett, Lewis H., 1982
8a	12		Saunders, Joseph F., 1981
8a	13		Schaeffer, Juergen, 1991-1997
8a	14		Schecter, Alan, 1981
8a	15		Schettler, Gotthard, 1981
8a	16		Schmid, Rudi, 1981-1982
8a	17		Schmidt, Benno C., 1982-1986
8a	18		Schultz, Julius, 1981
8a	19		Scientists' Institute for Public Information, 1981
8a	20		Scoular, Charring Connett, 1987-1995
8a	21		Setlow, Jane K., 1981-1982
8a	22		Seward, Ralph T., 1987
8a	23		Shelley, Julian H., 1981
8a	24		Sheps, Cecil G., 1981
8a	25		Sherwood, Bruce, 1996
8a	26		Simopoulos, Artemis, 1982
8a	27		Smith, Louis C., 1982
8a	28		Smith, Robert L., 1973
8a	29		Sokol, Herman, 1981
8a	30		Stadtman, Earl, 1981
8a	31		Stamatoyannopoulos, George, 1981
8a	32		Stark, Nathan, 1982
8a	33		Steinberg, Daniel, 1981-1982
8a	34		Stewart, William, 1982
8a	35		Stokes, Joseph, 1982
8a	36		Storey, Patrick B., 1981
8a	37		Temin, Howard, 1981
8a	38		Terrab, Aicha Aloui, 1982
8a	39		Thorton, Ray, 1982
8a	40		Timour, John A., 1981
8a	41		Tomizaura, Tom, [n.d.]
8a	42		Trivelpiece, Alvia, 1982
8a	43		Unger, Walter, 1982-1993
8a	44		Vagelos, P. Roy, 1982
8a	45		Wagner, Galen S., 1981
8a	46		Wall, James J., [n.d.]
8a	47		Ward, Lady Mary, 1976-1982
8a	48		Watt, James, 1961
8a	49		Weinberger, Caspar W., 1975
8a	50		Weissman, Sherman, 1982
8a	51		Whaley, Storm, 1981
8a	52		Whelan, William, 1980
8a	53		White, Paul Dudley, 1982
8a	54		Whitehead, Jack, [n.d.]
8a	55		Winkelstein, Warren, 1981
8a	56		Womeldorf, G. Raymond, 1978
8a	57		Woolf, Patricia, 1982
8a	58		Wormser, Ellen, 1981
8a	59		Wright, Lonnie M., 1981
8a	60		Xuma, Mtutuzeli, 1978-1981
8a	61		Yarmonlinsky, Adam, 1974
8a	62		Young, Leo, 1979-1982
8a	63		Zinder, Norton, 1981
8a	64		Unidentified, 1977-1991
			Job Offers, 1965-1982

8a	66			1965
8a	67			1966
8a	68			1967
8a	69			1969
8a	70			1970-1973
8a	71			1975-1979
8a	72			1980
8a	73			1981
8a	74			1982
8a	75			[n.d.]
			Congratulatory Letters, 1973-1977

				NAS

8a	76				A - I, 1973
8b	1				J - P, 1973
8b	2				R - Z, 1973
				IOM

8b	3				A - F, 1974
8b	4				G - L, 1974
8b	5				M - R, 1974
8b	6				S - Z, 1974
				NIH

8b	7				A - D, 1975
8b	8				E - J, 1975
8b	9				K - N, 1975
8b	10				O - R, 1975
8b	11				S - Z, 1975
8b	12				Reappointment Congratulatory Letters, 1977
			Recommendation Letters, A-Z, 1961-1995
						[RESTRICTED]
		Resignation Letters, 1981, 1987-1998

9	1		DSF's Announcement, 1981
9	2		Advisory Committee to the Director, NIH, 1981
9	3		Interagency Radiation Research Committee, 1981
9	4		House of Representatives and Senate, 1981
9	5		A - B, 1981
9	6		C - D, 1981
9	7		E - G, 1981
9	8		H - K, 1981
9	9		L - M, 1981
9	10		N - P, 1981
9	11		R - S, 1981
9	12		T - Z, 1981
9	13		HHMI Resignation Letters, 1987-1998
		Daily Letter Files, 1981-1982

9	14		Jun 1981
9	15		Jul 1981
9	16		Aug 1981
9	17		Sep 1981
9	18		Oct 1981
9	19		Nov 1981
9	20		Dec 1981
9	21		Jan 1982
9	22		Feb 1982
9	23		Mar 1982
9	24		Apr 1982
9	25		May 1982
9	26		Jun 1982
9	27		Jul 1982
9	28		Aug 1982
9	29		Sep 1982
9	30		Oct 1982
9	31		Nov 1982
9	32		Dec 1982
		Writing Engagements, 1966-1980

9	33		American Journal of Medicine, 1974-1975
9	34		American Physiological Society (Strydom-Hoffenberg), 1969-1970
9	35		American Physiological Society (ii), 1966-1969
9	36		Atherosclerosis, 1974-1975
9	37		Circulation Research, 1970-1976
9	38		Genetics, 1975
9	39		Invitations to Write, 1970-1973
9	40		JAMA, 1974-1976
9	41		Journal of Laboratory and Clinical Medicine, 1974-1975
9	42		Reviews - Misc., 1959-1980

Return to the Table of Contents



Series III: Writings, 1910-2001
	The Writings series contains both published (articles, essays, contributions to books, etc.) and unpublished (speeches, lectures, talks, eulogies, etc.) materials. The series is divided into four sub-series: Speeches and Unpublished Materials; Publications; Interviews; and Publications by Others. For the most part these materials are reprints, photocopies of typescripts, or printouts; occasionally these items are accompanied by associated correspondence or printed matter (e.g., programs or brochures).




	The Speeches and Unpublished Materials sub-series includes, but is not limited to, speeches, lectures, addresses, talks, and other presentations by Fredrickson. These files are divided into several categories, following Fredrickson's original organization. The first is composed of a six-volume set of speeches given by Fredrickson from 1975 to 1982. The speeches are individually numbered, and each volume has an index to its contents. The second consists of a collection of lectures and an essay ("The Unpublished Lectures - An Annotated Anthology of Lost Words") about these materials. Each lecture mentioned in the essay was given a number, and these numbers have been included in the titles of the folders. The third section includes the remaining unpublished works found scattered throughout the collection, including lectures, eulogies, speeches, drafts, etc.




	This series consists primarily of typewritten texts or photocopies; some correspondence, notes, and copies of programs are also included. Some of these pieces were later published, but are included here in their earlier unpublished form. Other items included here (eulogies, for example) were "published," but not widely distributed.




	Also included is a set of 8-inch floppy disks, which contain documents created with Wang word processing software. There is a list of the titles of these documents, but the contents of the disks are inaccessible until the digital information can be converted to a readable format.




	The Publications sub-series includes copies of articles, essays, and other published work by Fredrickson. For the most part these materials are reprints, photocopies of typescripts, or printouts; sometimes these items also have associated drafts, correspondence or printed matter (e.g., programs, brochures). Materials up to the late 1970s generally report on laboratory work; after that time they largely deal with broader biomedical issues - a change in focus reflecting Fredrickson's career shift from research to administration.




	The majority of reprints in this sub-series come from a volume entitled Selected Reprints and Lectures, which includes a bibliography created by Fredrickson in June of 1987; a smaller percentage have been removed from other parts of the collection and gathered here. Also of interest are the three microfilm reels of Fredrickson's publications created prior to March 1, 1979. These reels contain 207 published articles and several pamphlets, mostly concerning Fredrickson's scientific research. A list of these titles is included in the folder entitled "Publications of Dr. Donald Fredrickson Available for Microfilming as of March 1, 1979," box 11, folder 86.




Box	Folder
		Speeches and Unpublished Materials, 1942-1995

10	1		Book I Index, 1975 Sep - 1976 Nov 23
10	2		Book I #1-5, 1975 Sep - Dec 15
10	3		Book I #6-10, 1976 Feb 2 - Feb 19
10	4		Book I #11-15, 1976 Mar 3 - Apr 29
10	5		Book I #16-20, 1976 May 3 - Jun 4
10	6		Book I #21-25, 1976 Jun 8 - Oct 13
10	7		Book I #26-30, 1976 Nov 9 - Nov 23
10	8		Book II Index, 1976 Dec 9 - 1977 Dec 8
10	9		Book II #31-35, 1976 Dec 9 - 1977 Apr
10	10		Book II #36-40, 1977 Apr 4 - May 2
10	11		Book II #41-45, 1977 May 20 - Jun 27
10	12		Book II #46-50, 1977 Sep 12 - Sep 19
10	13		Book II #51-55, 1977 Sep 28 - Oct 25
10	14		Book II #56-60, 1977 Oct 27 - Dec 8
10	15		Book III Index, 1978 Feb 8 - 1979 Jan 17
10	16		Book III #61-65, 1978 Feb 8 - Apr 9
10	17		Book III #66-70, 1978 Apr 10 - May 11
10	18		Book III #71-75, 1978 May 31 - Jun 19
10	19		Book III #76-80, 1978 Jul 26 - Sep 14
10	20		Book III #81-85, 1978 Sep 17 - Oct 18
10	21		Book III #86-1990, 1978 Nov - Dec 12
10	22		Book III #91-1994, 1979 Jan 5 - Jan 17
10	23		Book IV Index, 1979 Jan 25 - 1980 Oct 9
10	24		Book IV #95-100, 1979 Jan 25 - Mar 14
10	25		Book IV #101-110, 1979 Apr 3 - 1980 Feb 5
10	26		Book IV #111-120, 1980 Feb 27 - May 6
10	27		Book IV #121-130, 1980 May 7 - Oct 9
10	28		Book V Index, 1980 Oct 10 - 1981 Jun 19
10	29		Book V #131-140, 1980 Oct 10 - Mar 30
10	30		Book V #141-151, 1980 Mar 31 - 1981 Jun 19
10	31		Book VI Index, 1981 Oct 15 - 1982 Nov 26
10	32		Book VI #151A-160, 1981 Oct 15 - 1982 Mar 3
10	33		Book VI #161-167, 1982 Apr 7 - Nov 26
10	34		The Unpublished Lectures (An Annotated Anthology of Lost Words), 1998 Feb 14
10	35		#1 Freedom From Want, 1942
10	36		#2 Newly Recognized Disorders of Cholesterol Metabolism, 1963 Apr 1-5
10	37		#3 A Sorcerer's Advice to His Apprentice, 1965 Aug
10	38		#4 The Second George C. Griffith Lecture: Diet, Genes and the Early Atheroma, 1969 Oct 1
10	39		#6 Research and the Prize, 1967 Nov 10
10	40		#8 Time for Renewal, 1981 Oct 15
10	41		#9 Biomedical Research: Today and Tomorrow, 1981 Sep
10	42		#10 Eulogy of Jan Laan, 1981 Sep
10	43		#11 AOA Lecture, Baylor University, 1982 Mar 23
10	44		#13 Science and the Culture Warp: rDNA as a Case Study, 1982 Jan 7
10	45		#14 Science and the Culture Warp: rDNA as a Case Study, 1982 Apr 7
10	46		#15 From LP Types to APO Isomorphs: The Status of Dyslipoproteinemia in 1982, 1982 Apr
10	47		#16 Address to the Board, Miriam Hospital Corporation, 1982 May 13
10	48		#17 The State of the Union, 1982 May 26
10	49		#18 Guelph in Green, 1983 Sep 30
10	50		#19 The Knowledge Imperative, 1984 Feb 7
10	51		#20 Medical Science, Thomas Paine and H.R. 5098, 1984 Apr 11
11	1		#21 Diastole (Notes of a Cardiology Watcher), 1984 Nov 12
11	2		#22 Comparative Professions Part 1, 1985 May 24
11	3		#23 Shaping a Mission, 1986 Sep 5
11	4		#24 The Big Table, 1987 Sep 21
11	5		#25 The Health of Science, 1987 Oct 17
11	6		Acceptance of Presidency of Institute of Medicine, 1974 May 8
11	7		Ad Hoc Committee on Government-University Relationships in Support of Science, [ca. 1981]
11	8		Après Consensus, le Déluge, 1989 Jan 26
11	9		Asilomar: The End of the Beginning, 1990
11	10		Beacon of Hope: The Clinical Center Through 40 Years of Growth and Change in Biomedicine, 1944-1984, [1993?]
11	11		Chairman's Remarks, 1990 Oct 9
11	12		Chemistry and Health, 1982 Jan 7
11	13		Clinical Center Origins, 1993 Jul 9
11	14		Columbia Talk, 1994 Dec 9
11	15		[Columbia Talk], 1995 Jun 9
11	16		[Eulogy for] Ernest William Goodpasture, 1972 Feb 21
11	17		[Eulogy for] James Augustine Shannon, 1994
11	18		[Eulogy for] James Augustine Shannon, 1996 Mar
11	19		[Eulogy for] Max Boulin, [ca. 1985?]
11	20		[First and Second] Draft Reports of the Subcommittee on Principles, 1982 Jan 4
11	21		Gene Therapy: The Promise and the Problems of Providing Normal Genes to Treat Human Genetic Abnormalities, 1986 Nov 27-29
11	22		The Government Role in the Recombinant DNA Controversy, 1982 Jan 7
11	23		Graduate Education and Research, [n.d.]
11	24		A History of Recombinant DNA Guidelines in the United States, 1979 May 22
11	25		Impressions from the Interface, 1987 Jul 12
11	26		Improving Detection and Management of Those Susceptible to Premature Vascular Disease, [1970]
11	27		Intramural Program of NIH, 1972 Apr 7
11	28		Introductory Notes on a Bibliography, 1978 Oct
11	29		IOM: Mémoires À L'Accouchement, 1990
11	30		NHLI, Clinical Research Today and Tomorrow, 1973 Jul 6
11	31		Notes on an Editorial, 1979 Feb 6
11	32		Opening Remarks [from a Symposium in Memory of Gordon Tomkins], 1976 Feb 2
11	33		Opening Statement: Testimony before the House Committee on Science and Technology, 1986 Apr 23
11	34		Our Common Faith, 1981 Nov 8
11	35		Pitfalls and Promises in Contemporary Support of Science in Universities, 1981 Oct 20
11	36		Remarks [on the] Receipt of Distinguished Contribution to Research Administration Award, 1982 Sep 13
11	37		Remarks on Receipt of Honorary Degree, Rochester University Medical School, 1986 May 25
11	38		Remarks to the NIH Community [Resignation Speech], 1981 Jun 19
11	39		The Role of the Government in the Support and Shaping of Academic Medicine, [1981-1983]
11	40		Science: The Endless Frontier, Columbia University, 1994-1995
11	41		Slide Session on Hyperlipoproteinemia, [n.d.]
11	42		Statement of DSF, Former Director of the NIH and Member of the White House Science Council, 1988 Feb 17
11	43		Stockholm Reflections, 1979 Feb 5
11	44		Science and the Culture Warp: rDNA as a Case Study, 1982 Apr 7
11	45		Testimony of Donald S. Fredrickson, President and CEO, Howard Hughes Medical Institute, before the Subcommittee on Health and Long Term Care of the House Select Committee on Aging, 1987 Mar 6
11	46		University of Michigan, 25th Anniversary of the Clinical Center, 1982 Oct 29
11	47		Wang Documents, 1982-1983
		Publications, 1964-2001

11	48		Speeches, Articles and Selected Papers [Bibliography], 1976
11	49		Bibliography I, 1987 Jun
11	50		Publications by DSF on Research Related to Plasma Lipids and Lipoproteins, [n.d.]
11	86		Publications of Dr. Donald Fredrickson Available for Microfilming as of March 1, 1979, 1979
13			Dr. D.S. Fredrickson nos. 1-99 [Microfilm], 1979
13			Dr. D.S. Fredrickson nos. 100-183 [Microfilm], 1979
13			Dr. D.S. Fredrickson nos. 184-207 and Pamphlets [Microfilm], 1979
11	51		Abnormal Concentration and Anomalous Distribution of Alipoprotein A-I in Tangier Disease, 1978 Feb
11	52		Aesculapian Merry-Go-Round, 1976 Oct
11	53		Biomedical Research in the 1980s, 1981 Feb 26
11	54		Biomedical Science and the Culture Warp, 1993
11	55		Birth Defects Compendium, 1982
11	56		Camelot-in-Bethesda: The Roots of the Magic Kingdom, 1991 Feb 15
11	57		A Comparison of Heritable Abnormal Lipoprotein Patterns as Defined by Two Different Techniques, 1968
11	58		Communal Resources, Community Responsibilities, 1981
11	59		Cutaneous Cholesterol Ester Deposition in Tangier Disease, 1967
11	60		Discours: Acadámie du Royaume du Maroc, 1982 Nov 29
11	61		Dyslipoproteinemia: From Phenotypes to Genotypes ... A Remarkable Quarter Century, 1993 Apr
11	62		Fat Transport in Lipoproteins - An Integrated Approach to Mechanisms and Disorders, 1967 Jan-Feb
11	63		Finding Answers to Health Care Problems, 1975 Oct
11	64		Functions of Plasma Lipoproteins, [ca. 1967]
11	65		The Government Role in Biomedical Research, 1976 Jun 8
11	66		Health and the Search for New Knowledge, 1977
11	67		A History of Recombinant DNA Guidelines in the United States, 1981 May
11	68		In Defense of Washington, 1986 Oct 7
11	69		Introduction: The Anfinsen Series, [ca. 1984?]
11	70		Is There a Federal Philosophy about Academic Medicine?, 1980 Oct 10
11	71		Lilly Lecture, 1982 Apr 29
11	72		Lipoprotein Patterns and Atherosclerosis, [n.d.]
11	73		The Meaning of the Prize, 1980
11	74		The National Institutes of Health: Yesterday, Today, and Tomorrow, 1978 Nov 12
11	75		Neuropathy in Tangier Disease, 1967
11	76		On Cultivating Prognosis in Cardiovascular Research, 1968
11	77		On the Cultivation of Virtue, 1983
11	78		Overview Statement of the National Conference on Health Research Principles, 1979
11	79		The Pathology of Tangier Disease, 1975
11	80		Proceedings - Joseph C. Wilson Day, 1977
11	81		The Public Governance of Science, 1976 Dec 9
11	82		The Recombinant DNA Controversy: A Memoir, 2001
11	83		The Recombinant DNA Controversy: The NIH Viewpoint, 1986
11	84		Review of "Puzzles, Problems, and Enigmas" in Nature, 1982 Aug 2
11	85		The Rights of Man and the World Wide Web, 1996 Apr 22
12	1		Seeking Technical Consensus on Medical Interventions, 1978
12	2		Snippets of Science, 1982 Jul 15
12	3		Sorting Out the Doctor's Bag, 1980
12	4		Stockholm Reflections, 1979 Feb 10
12	5		Tangier Disease (Familial Cholesterolosis with High-Density Lipoprotein Deficiency), 1962
12	6		Tangier Disease (Familial High Density Lipoprotein Deficiency), 1964 Oct 26
12	7		Tonsils and Alipoproteins: Lesson about Plasma Lipoproteins Derived from Tangier Disease and Other Mutants, 1974
12	8		Two Challenges to Negative Prophecy: 'Clinical Applications Units' and 'The Cloister Project', 1984 Jul 21
12	9		The Use of Animals in Biomedical Research [Panel Discussion], 1984 May
12	10		Values and the Advance of Medical Science, 1990
12	11		"Venice" is not Sinking (The Water is Rising), 1982 Jun 11
12	12		Welcoming Remarks, 1978 Nov 30
		Interviews, 1979, 1986

12	13		A Conversation with Donald Sharp Fredrickson, 1979
12	14		An Interview with Dr. Donald S. Fredrickson by Stephen P. Strickland, Ph.D., 1986 Oct
		Publications by Others, 1910-1995

12	15		Ahuja, M. M. S., et al. - Interrelationship of Vascular Disease and Blood Lipids in Young Indian Diabetics, 1969
12	16		Ahuja, M. M. S., and V. V. Gossain - Dietetic Analysis and Blood Lipids, Chemical and Isotopic Studies in Vascular Disease among Indian Diabetics, 1967
12	17		Albertine, A. von - Gutartige Riesenzellgeschwülste, 1928
12	18		Archiv für Dermatologie und Syphilis, 1921-1933
12	19		Archiv für Gynäkologie, 1927
12	20		Archiv für Klinische Chirurgie, 1931
12	21		Archiv für Ophthalmologie, 1925
12	22		Archiv für Pathologische Anatomie und Physiologie, 1924
12	23		Archiv für Wissenschaftliche Praktische Tierheilkunde, 1930
12	24		Bergen Stanley S. - The Hastings Center Activities Report, 1987 Nov
12	25		Bernard, Jean - Donald Fredrickson, 1982 Nov 24
12	26		BioRad Laboratories - Lipoprotein Phenotyping by Agarose Gel Electrophoresis, 1970 Jan
12	27		Bloch, Bruno - Metabolism, Endocrine Glands and Skin Diseases, with Special Reference to Acne Vulgaris and Xanthoma, 1931
12	28		Bosch, V. et al. - Lípidos y Lipoproteínas Sericas en Personas Normales y Pacienes con Cardiopatía Isquémica, 1970
12	29		Brinkley, Joel - The Richest Foundation, 1986 Mar 30
12	30		Brooks, Harvey - Research Universities and the Social Contract for Science, 1993 May 9
12	31		Brown, Helen B. - Food Patterns That Lower Blood Lipids in Man, 1969 Nov
12	32		Brown, Helen B. - The Market Basket, [n.d.]
12	33		Carter, Luther J. - State Scientific Advisers: The Effort in Michigan, 1976 Nov
12	34		Clifton-Bligh, P., et al. - Tangier Disease: Report of a Case and Studies of Lipid Metabolism, 1972 Mar
12	35		Consensus Development Conference - The Consensus Development Process for Medical Technologies, 1982
12	36		Culliton Barbara J. - NIH: Who is Running the Show: Scientists or Politicians?, 1974 Mar 1
12	37		Curtis, A. C., et al. - The Involution of Cutaneous Xanthomata Caused by Diets Low in Calories, 1929
12	38		Dirks, Harley - Departments of Labor and Health, Education and Welfare, and Related Agencies Appropriations, Part 2, 1979
12	39		Eckstein, H. C. and Udo J. Wile - The Cholesterol and Phospholipid Content of the Cutaneous Element of Man, 1926
12	40		Ergebnisse der Innere Medizin und Kinderheilkunde, 1928
12	41		Ergebnisse der Lipoidstoffewechselforschung, 1928
12	42		Fasold, Anna von - Studien über Verebung von Hautkrankheiten, [ca. 1925]
12	43		Fleischmajer, Raul and Alan M. Schragger - Familial Lipoproteins, [n.d.]
12	44		Flint Laboratories - The Five Faces of Hyperlipidemia, 1973 Mar
12	45		Fox, Renée C. et al. - The Study of the Sick, 1991 May 20-21
12	46		Frank, Allen Dodds - Killing the Goose?, 1984 Oct 22
12	47		Gaál, Andreas M. - Untersuchungen über Cholesterinstoffwechsel bei Xanthomatotis Essentialis, 1930
12	48		Gilbert-Hamburg, W. von - Über Xanthomatose der Hornhaut und Lederhaut, 1925
12	49		Goe, Don R. - Hyperlipidemia: Origin, Identification, Characterization and Clinical Significance, 1970 Aug
12	50		Grosse, F. [Review] - The Metabolic Basis of Inherited Disease, 1961
12	51		Grouse, Lawrence D. - A Medical Misdemeanor: I Harbored Evil Thoughts About the Fredrickson Fat Classification, 1980 Nov 7
12	52		Hatch, F.T. et al. - Semi-Quantitative Paper Electrophoresis of Serum Lipoproteins, 1970
12	53		Haust, M. Daria - Tribute to Dr. Robert W. Wissler, the 1994 D.S. Fredrickson Career Awardee, 1995
12	54		Hitachi, Masahito - Tumors in Fishes, [ca. 1976]
12	55		Hoffman, Alan F. - Presentation of the Julius M. Friedenwald Medal of the American Gastroenterological Association to Dr. Hugh Roland Butt: A Laudation, 1979 May 21
12	56		Holden, Constance - NIH moves to debar cholesterol researcher, 1986
12	57		Howard Hughes Medical Institute - Bulletin, 1997 May
12	58		Howard Hughes Medical Institute - A New Opportunity for Research Careers in Medicine, 1985
12	59		Hubbard, William N. - The Educational Environment in the Large Medical School, 1967 Jul
12	60		Hunter, J. D. - Diet, Body Build, Blood Pressure, and Serum Cholesterol Levels in Coconut-eating Polynesians, 1962
12	61		Hunter, J. D., et al. - The Mobilization of Free Fatty Acids in Relation to Adipose Tissue Triglyceride Fatty Acids in the Rat, 1970
12	62		Hunter, J. D. and L. C. K. Wong - Plasma Cholesterol Levels in New Zealand, 1961
12	63		Iglehart, Joan K. - The NIH Appropriation, 1984 Oct 25
12	64		International Summer School on Pathological Neurochemistry - Symposium on Cerebral Lipidosis, 1967
12	65		JAMA Medical News - Questions Surround the Treatment of Children with High Cholesterol, 1970 Dec 7
12	66		Jensen, Julius - The Story of Xanthomatosis in England Prior to the First World War, 1967
12	67		Kennedy, Edward - Partners of Protagonists - Congress and the Academic Medical Centers, 1974 Dec 2
12	68		Kocen, R. S., et al. - Familial a-Lipoprotein Deficiency (Tangier Disease) with Neurological Abnormalities, 1967 Jun 24
12	69		Kummer, H., et al. - Familiäre Analphalipoproteinäimie (Tangier-Krankheit), 1968
12	70		Maxwell, William - Grape Bay (1914), 1999
12	71		Milbradt, W. - Lipämiestudien, [ca. 1925]
12	72		Morrow, Lance - Religious Wars, 1975 Oct
12	73		National Institutes of Health - Centennial Highlights, 1987
12	74		National Institutes of Health - Centennial Highlights, 1987
12	75		National Institutes of Health - Population Strategies for Blood Cholesterol Reduction, [ca. 1989]
13	1		National Institutes of Health - Research Plan, 1980
13	2		National Institutes of Health - USA-Russia: 20 Years of Cooperation in Cardiopulmonary Research, 1992
13	3		National Heart, Lung and Blood Institute - A Salute to the Past, 1987 Sep
13	4		National Science Foundation - American Science Manpower, 1968, 1970 Jan
13	5		Norman, Colin - The Threat to Peer Review, 1976 Apr 29
13	6		O'Leary, Paula and Hamilton Montgomery - Xanthomatoses, 1947
13	7		Page, Irvine H. - Steering Clear of the Federal Bureaucracy, 1976 Sep 1
13	8		Perry, Seymour - The NIH Consensus Development Program: A Decade Later, 1987
13	9		Peter Bent Brigham Hospital - Annual Report, 1949-1950
13	10		Pollitzer, S. - The Nature of the Xanthomata, 1897
13	11		Rey, Louis - Fundamental Aspects of Lyophilization, [ca. 1975?]
13	12		Rey, Louis - Glimpses into the Fundamental Aspects of Freeze-Drying, 1976
13	13		Rey, Louis - New Adventures in Freeze-Drying, 1990 May 10
13	14		Rogers, David E. and Eli Ginzberg - The Metropolitan Academic Medical Center, 1995
13	15		Schaaf, Fritz - Der Lipidstoffwechsel, [ca. 1925]
13	16		Schweiker, Richard S. - Dedication of the Magnuson Clinical Center: A National Treasure, 1982 Apr
13	17		Scott, P. J. - Preliminary Study of Family with Hereditary Hypercholesterolæmic Xanthomatosis, 1961
13	18		Shacklady, Maureen M., et al. - Red-cell Lipids in Familial Alphalipoprotein Deficiency (Tangier Disease), 1968 Jul 20
13	19		Siemens, Hermann Weiner - Zur Kenntnis der Xanthone, 1921
13	20		Simmons, Roberta G. - Issues of Informed Consent, 1976 May 28
13	21		Sonderabdruck aus Klinische Wochenschrift, 1922, 1931
13	22		United Medical Laboratories - The Serum Lipid Profile and Hyperlipidemia, [n.d.]
13	23		United States Congress - An Agenda for a Study of Government Science Policy, 1985
13	24		United States Congress - Agriculture, Rural Development and Related Agencies Appropriations for 1979, 1978
13	25		United States Congress - Compilation of Selected Acts within the Jurisdiction of the Committee on Energy and Commerce, 1986 Mar
13	26		United States Congress - Compilation of Selected Acts within the Jurisdiction of the Committee on Energy and Commerce, 1990 Jun
13	27		[Unknown] - [Jimmy Carter's Visit to Morocco], [n.d.]
13	28		Unna, P. G. - Dem Hamburger Dermatolgen, 1910
13	29		Urbach, Erich - Imbibitio Lipoidica Telae Elasticae Degeneratae, 1934
13	30		Urbach, Erich - Lipoidstoffwechselerkrankungen Der Haut, 1931
13	31		Urbach, Erich and William R. Hill - A Proposed Classification of Cutaneous Lipoidoses, 1940
13	32		Urbach, Erich - Über Lipoidsen mit Cutanen Erscheinugen, [n.d.]
13	33		Urbach, Erich - Zusammenfassende Arbeiten Diagnostichen und Therapeutischen Inhalts, 1933
13	34		Urbach, Frederick, et al. - The Therapeutic Uses of Low Fat, Low Cholesterol Diets, 1952
13	35		US News and World Report - [National Heart Institute Report], 1959 Feb 27
13	36		US News and World Report - Who Runs America?, 1981 May 18
13	37		Wade, Nicholas - Send Not to Know for Whom the Nobel Tolls: It's Not for Thee, 1978 Oct
13	38		Ward, Sinclair - Disease of the Month Clubs' Clamour for Dues, 1980 Mar 20
13	39		Watkins, Robert - Drs. Stone, Edwards Exit Amid Continuing Discontent at NIH, 1975 Feb 1
13	40		Wile, Udo J. and Werner Duemling - Familial Xanthoma, 1930
13	41		Wile, Udo J., et al. - Lipid Studies in Xanthoma, 1929
13	42		Wood, Margaret Gray, et al. - Histochemical Study of a Case of Lipoid Proteinosis, 1955
13	43		Zietschrift für die Gesamte Experimentelle Medizin, 1925
13	44		Zietschrift für Kinderhelkunde, 1924

Return to the Table of Contents



Series IV: Recombinant DNA Materials, 1947-2001 (bulk 1974-1989)
	The Recombinant DNA Materials Series contains files compiled by Fredrickson in preparation for his book, The Recombinant DNA Controversy: A Memoir. The monograph reveals his involvement as director of NIH specifically during debates in the U.S. Congress, and among scientists, concerning rDNA experiments and the establishment of NIH guidelines on the use of rDNA molecules. The book itself is included in the Publication sub-series of Series III: Writings. The series is divided into 16 sub-series. Materials in each sub-series include reprints, correspondence, memos, notes, newspaper articles, etc. These materials tend not to be original documents, but rather photocopies of the originals, along with additional comments by Fredrickson, which he created on his computer and printed out. The digital files are no longer available, but Fredrickson preserved their original arrangement in his paper filing system, noting the titles of the original hard drive directory and sub-directory on each item. Most folders include a brief summary of their contents.




	The materials in the folders remain in their original order. In order to preserve the original organization of these materials, sub-series titles were duplicated from the top-level file naming structure found on his computer. Fredrickson discusses his file arrangement system for this series on his computer in the beginning of an interview on audiotape entitled "Fredrickson on the Recombinant DNA Controversy," in the Audio Materials sub-series of Series XI: Audio-Visual Materials. This tape also provides a personal account of the events surrounding the rDNA controversy.




	Fredrickson's sub-divisions tend to be chronological. Whenever possible, his original abbreviations have been expanded to their full terms. When years are used as sub-series titles, they refer to the dates of the events discussed in the materials, not the actual dates of the documents. The sub-series are arranged with the Index sub-series first, followed by the year-titled sub-series (which includes the Asilomar sub-series in the original arrangement), and then the subject-titled sub-series in alphabetical order. Reprints of others' publications from Fredrickson's rDNA research and activities are the last sub-series. Folders within each sub-series are arranged alphabetically by title with three minor exceptions where "index," "contents," and "chronology" appear first.




	The General sub-series consists of two divisions identified as AAGENL and DNAGENL, which stand for "general." Any unlabeled folders were also placed in the General sub-series. These files include general information on rDNA, files on key players in the rDNA controversy, event chronologies, and Fredrickson's notes and annotations.




	The Asilomar sub-series consists of information concerning the Asilomar conference on the dangers of genetically reengineered microorganisms. The meeting was organized by future Nobel laureate Paul Berg and held in February 1975 at Pacific Grove, California. The conference voluntarily endorsed what would become the seminal moratorium on rDNA experiments with E. coli bacteria and certain other organisms. It was the first time that scientists in any discipline had voluntarily adopted a moratorium on experiments in a new field of research. The principles formulated at Asilomar served as the basis for the development of the detailed technical guidelines on containment facilities and safety procedures in rDNA research of the NIH Guidelines. Materials in this sub-series served as research materials for Chapter 1 of The Recombinant DNA Controversy.




Box	Folder
		Index, 1989

14	1		Index of ASKSAM Document Entries, 1989
14	2		[Index for 1975-1979], [1989?]
		General, 1974-2001

14	3		Contents - Files on DNA (PC) Diskettes, [n.d.]
14	4		Chronology, 1988 Sep 21
14	5		ABC, 1977-1995
14	6		Author's Notes, 1997-1999
14	7		Book, 1990-1991
14	8		Cloning Man, Early Refs, 1978-2001
14	9		Contentious Views, 1974-1996
14	10		DSF Notes, 1981-1988
14	11		DSF Notes, 1989
14	12		DNAGENL, 1977-1980
14	13		DNA Extra Sources, 1979-1996
14	14		DNA Michigan Meeting, 1976
14	15		DNA Press Notes, 1978-1980
14	16		EIA (Environmental Impact Statement), 1978
14	17		Environmental Impact Statement, 1977-1978
14	18		Executive RAC, 1977
14	19		Federal Register, 2000
14	20		Gene Therapy, 1980-1999
14	21		[Genetic Engineering Play], [n.d.]
14	22		Hans Stetten Papers, 1978-1985
14	23		IBC [International Biosafety Committees], 1981-1998
14	24-25		Industry, 1976-1980
14	26		Insurance, 1977
14	27-28		Interagency Interactions, 1977-1980
14	29		Interagency Subcommittees (Meetings), 1977
14	30		Kitchen RAC, 1978
15	1		Legislation Summary, 1977-1989
15	2		Libassi Committee, 1978
15	3		Litigation, 1977-1979
15	4		[Loose Notes], [n.d.]
15	5		MIT DNA Collection Finding Aid, 1988
15	6		[Ou, Jonathan and Anderson, Thomas], 1978
15	7-9		Patent, 1977-1981
15	10		Politics, 1993-1994
15	11		Pyoloma and Mack Suit, 1978
15	12		Quotes, 1978
15	13		RAC Documents, 1979-1989
15	14		[RAC Members], 1978-1999
15	15		RAC Minutes, 1988 Oct 3
15	16		Recombinant Odyssey, 1976-1977
15	17		Recombinant Odyssey, 1977-1990
15	18		Recombinant Odyssey - Denmark, 1990
15	19		Recombinant Odyssey - Finland, 1990
15	20		Recombinant Odyssey - UK2, 1990
15	21		Retrospectives, 1999-2000
15	22		Risk Assessment, 1977-1979
15	23		Section 361, 1978-1988
15	24		Stem Cell Research, 2001
15	25		Wright, [Susan], 1976-2001
		[Events of the] 1960s, 1947-1989

15	26		Asilomar, 1973
15	27		Curtiss, [Roy], 1974
15	28		Molecular Biology, 1947-1989
15	29		NIH, 1974
		Asilomar, 1966-1995

15	30		Appendix, 1975
15	31		Berg, P., 1966-1976
15	32		Final Manuscript, 1990-1991
15	33		Interviews, 1972-1990
16	1-3		Interviews (cont'd.), 1972-1990
16	4		Meeting Tapes, 1975-1989
16	5		MIT Archives Documents, 1972-1975
16	6		National Academy of Science Archives Documents, 1973-1989
16	7		NIH Central File, 1974-1975
16	8		Participant List, 1975
16	9		Pre-Asilomar, 1973-1974
16	10		References, 1970-1975
16	11-13		References - Books, 1977-1990
		[Events of] 1975, 1973-1996

16	14		Chapter 2 - RAC and Background Notes, 1974-1979
16	15		Correspondence, 1974-1995
16	16		Guideline Sets, 1976
16	17		News Editorials, 1975
16	18		News Editorials Summaries, 1975
16	19-20		RAC Minutes and Charter, 1974-1995
16	21		RAC Working References, 1975-1996
16	22		Stetten, DeWitt, 1973-1995
		[Events of] 1976, 1975-1989

16	23		ADHEW, 1976-1989
16	24		Cambridge, 1976-1977
16	25		Correspondence, 1976
16	26		Critique of NIH, 1976
16	27		DAC February, 1976
17	1		Draft, Environmental Impact Statement, 1976
17	2		FACA Notes, 1975-1997
17	3		First Public Review of NIH Guidelines, 1975-1976
17	4		Guidelines Versions Regulations, 1976-1989
17	5		Interagency Committee Birth, 1976-1977
17	6		Interagency Committee Meeting, 1976 Nov 4
17	7		Interagency Committee Meeting, 1976 Nov 23
17	8		Legislation, 1976
17	9		Memo from Ford, 1976 Sep 22
17	10		News Editorials, 1976
17	11-12		NIH Guidelines, 1976-1986
17	13		ORDA (Office of Recombinant DNA Activities), 1976
		[Events of] 1977, 1976-1977

17	14		Administration Bill, 1977
17	15		Correspondence, 1977
17	16-17		DAC Meeting, 1977 Dec 15-16
17	18		Debate, 1977
17	19		DNA Bills, 1977
17	20		Falmouth, 1977
17	21		Final Environmental Impact Statement, 1976-1977
17	22		FOE Seeks Injunction, 1977
17	23		Forums, 1977
17	24		Green Diary, 1977
17	25		Guideline Revisions, 1977 Jan-Sep
17	26		Guideline Revisions after September 1977, 1977-1978
		Interagency Committee Meetings

17	27		1977 Feb 25
17	28		1977 Mar 10-14
17	29		1977 Mar 29
18	1		1977 Apr 8
18	2		1977 May 6
18	3-15		Legislation, 1977
18	16		Legislation Summary, 1977
18	17		NAS Forum, 1977 Mar 7-199
18	18		News Editorials, 1977
18	19		Recombinant Reflections Diary, 1986
18	20		Senator Stevenson, [Adlai], 1977-1978
18	21		Special Meeting, 1977 Feb
18	22		State Legislation, 1977
19	1		State Legislation (cont'd.), 1977
19	2		US Guidelines Abroad, 1977
		[Events of] 1978, 1977-1980

19	3		Ascot/Plant, 1978
19	4		Correspondence, 1978
19	5		DNA Bills, 1978
19	6		Executive rDNA Committee, 1978
19	7-8		Forming NeoRAC, 1977-1980
19	9-10		Green Diary, 1978
19	11		Green; Krimsky; UK, 1978
19	12		Guidelines Revisions, 1978 Jul 28
19	13-21		Legislation, 1978
19	22		Legislation Info, 1978
19	23		Libassi, Peter, 1976-1978
19	24		News Editorials, 1978
19	25		Post DAC II Revision, 1978
19	26		Risk Assessment, 1978
19	27		State Legislation, 1978
		[Events of] 1979, 1979-1997

19	28		Assessing the Risks of rDNA Research, 1979
19	29		Correspondence, 1979
19	30		DNA Hisbytes, 1979-1997
19	31		Green Diary, 1979
19	32		Legislation, 1979
19	33		Neo-RAC, 1979
19	34		News Editorials, 1979
20a	1		RAC, 1979-1995
20a	2		Reprisal to Singer Editorial, 1979
20a	3		Shuster & Cantley, 1979-1994
20a	4		Singer, 1979
20a	5		State Legislation, 1979
		[Events of the] 1980s, 1980-1989

20a	6		AAAS Symposium, 1981
20a	7		Correspondence, 1981-1987
20a	8		General, 1985-1987
20a	9		GD, 1980
20a	10		Judge Wright's Rulings (NIH), 1985
20a	11		Legislation, 1980-1985
20a	12		Letter to Members of RAC, 1981
20a	13		Litigation, 1984-1987
20a	14		News Editorials, 1974-1989
20a	15		RAC, 1981
20a	16		RAC Meeting, 1980 Jun 5-6
20a	17		Secretary Harris, 1980
		[Events of the] 1990s, 1974-2000

20a	18		Advisory Committee on Genetic Manipulation, 1990-1994
20a	19		American Society of Microbiology, 1996
20a	20		Asilomar II Celebration, 1999-2000
20a	21		Biotechnology Science Coordinating Committee, 1989-1990
20b	1		Biotechnology Science Coordinating Committee (cont'd.), 1989-1990
20b	2		Cloning Man, 1997-1998
20b	3		Environmental Regulations (EASE), 1988-1990
20b	4		Gene Therapy, 1990
20b	5-6		Gene Therapy - Earlier References, 1982-1999
20b	7		Legislation, 1990
21	1		Mortis RAC, 1996-1998
21	2		Organization for Economic Cooperation and Development (OECD), 1990
21	3		Post-book, 1999
21	4		Present Biotech, 1996-1998
21	5-6		RAC 1977 to 1990, 1974-1990
21	7		RAC 1990, 1989-1990
21	8		RAC, 1991
21	9		RAC/Biotech, 1993-1994
21	10		RAC General, 1979-1999
21	11-12		Recombinant Odyssey II/European Community, 1989-1990
21	13		Recombinant Odyssey II/France, 1990
21	14		Recombinant Odyssey II/FRG (Federal Republic of Germany), 1989-1990
21	15		Recombinant Odyssey II/Holland, 1990
21	16-17		Recombinant Odyssey II/UK, 1989-1992
21	18		State Regulations, 1991
		Drafts, 1998-1999

21	19		Archive Summary of "Memoir", 2001 Jan 1
21	20		Synopsis, 1999
21	21		Preface, 1999
21	22		Chapter 1: Asilomar, 1989
21	23-27		Chapter 1-4, 1999
22	1-15		Chapter 4 (cont'd.)--Chapter15, 1998?
22	16		Outline of First Version, 1999
22	17		[Outlines and Overviews], [n.d.]
		Guidelines, 1975-1986

22	18		1980s Revisions, 1986
22	19		Concern, 1975-1980
22	20		Definition, 1976-1978
22	21		Dissent, 1977-1980
22	22		Dissent/Laity, 1977
22	23		Dissent/Lay Public, 1978-1980
22	24		Dissent/Scientists I, 1977
22	25-27		Dissent/Scientists II, 1976-1979
22	28		General, 1981
22	29		Guideline Revision Retroactive, 1978-1994
23	1-2		Pro-rDNA, 1976-1980
23	3		Technical Bulletin, 1977-1985
		International, 1974-1984

23	4		Canada, 1975-1977
23	5		CEC, 1978
23	6		COGENE, 1974-1984
23	7		EMBO, 1976-1977
23	8		EMBO, 1978-1980
23	9		EMRC, 1977-1978
23	10		ESF, 1976-1981
23	11		Germany, 1976-1979
23	12-13		GMAG, 1975-1979
23	14		Other (A-H), 1976-1977
23	15		Other (I-Z), 1976-1978
23	16		USSR, 1976-1977
24	1		WHO, 1976-1977
		Violations, 1977-1981

24	2		Cline Affair, 1980-1981
24	3-7		Cline Case, 1980-1981
24	8		General, 1977-1978
24a	1		Guideline Violations, 1977-1978
24a	2		University of California San Francisco, 1977
		Reprints, 1975-1998

24a	3		Addendum to Comments on NIH Proposed Revised Guidelines for rDNA Research, 1977 Sep 27
24a	4		An Agenda for a Study of Government Science Policy, 1985
24a	5		Asilomar: The End of the Beginning, 1990 Jan 30
24a	6		Asilomar: The End of the Beginning, 1990 Apr 9
24a	7		The Case for Continuation of the European Molecular Biology Conference and its General Purpose Executed by the European Molecular Biology Organization, 1978 Jun
24b	vol.		Biotechnology and the Law: Recombinant DNA and the Control of Scientific Research, 1978 Sep
24b	vol.		Departments of Labor and Health, Education, and Welfare Appropriations for 1980, 1979
24b	vol.		DNA Recombinant Molecule (Research Supplemental Report II), 1976
25	1		Environmental Impact Statement on NIH Guidelines Involving Recombinant DNA Molecules Part 1, 1977 Oct
25	2		Federal Register, 1979 Jan 15 - 1979 Jul 20
25	3		Federal Register, 1980 Jan 17 - 1982 Aug 27
25	4		Federal Register, 1983 Jan 10 - 1984 Nov 23
25	5		Federal Register, 1985 Mar 11 - 1989 Mar 13
25	6		Federal Register, 1998 Feb 17, 1999 Feb 17
25	7		Federal Research: The National Academy of Sciences and the Federal Advisory Committee Act, 1998 Nov
25	8		Field Testing Genetically Modified Organisms, 1989
25	9		First Report to COGENE from the Working Group on Risk Assessment, 1978 Jul
25	10		Health and Safety at Work, 1976
25	11		Human Gene Therapy: Scientific and Ethical Considerations, 1985
25	12		Human Gene Therapy, Volume 1 Number 1, 1990
25	13		In Defense of DNA, 1978 Aug
25	14		Industrial Applications of Recombinant DNA Techniques, 1980 May 20
25	15		International Symposium on Genetic Engineering, 1978 Mar 29-31
25	16		[Japanese Guidelines for rDNA Research], 1979
25	17		The New Human Genetics, 1984 Sep
25	18		NIH Guidelines for Research Involving Recombinant DNA Molecules, 1994 Jun
25	19		NIH Guidelines for Research Involving Recombinant DNA Molecules, 1995 Apr
25	20		NIH Guidelines - Recombinant DNA Research, 1976 Jul 7
25	21		NIH Guidelines - Recombinant DNA Research - Proposed Revised Guidelines, 1978 Jul 28
25	22		NIH Guidelines - Recombinant DNA Research - Revised Guidelines, 1978 Dec 22
25	23		NIH Review of Intramural Research, 1961
25	24		The Patenting of Recombinant DNA Research Inventions Developed Under DHEW Support, 1977 Nov
25	25		Poorly-developed legislation to ban human cloning could inhibit life-saving research, says industry representatives, 1998 Jul 17
25	26		Recombinant DNA Regulation Act Hearing, 1977 Apr 6
25	27		Recombinant DNA Research Vol. 1, 1976 Aug
25	28		Recombinant DNA Research Vol. 1 [Fredrickson annotated], 1976 Aug
25	29		Recombinant DNA Research Vol. 2, 1978 Mar
26	1-8		Recombinant DNA Research Vol. 2 - Vol. 7 [Fredrickson annotated], 1978
27	1		Recombinant DNA Research Vol. 9 [Fredrickson annotated], 1986 Mar
27	2		Recombinant DNA Research Act of 1977, 1977 Mar
27	3		Recombinant DNA Research Act of 1978, 1978 Apr 11
27	4		Recombinant DNA Research and its Applications, 1978 Aug
27	5		Recombinant DNA Safety Considerations, 1986
27	6		Recombinant DNA Technical Bulletin, 1977
27	7		The Regulation of Modern Biotechnology: A Historical and European Perspective, 1995
27	7a		Regulation of Recombinant DNA Research, 1977 Nov
27	8		The Release of Genetically Engineered Organisms to the Environment, 1989 Jul
27	9		Report of the Committee in Charge of the Control on Genetic Manipulation, 1977 Mar
27	10		Report to COGENE from the Working Group on rDNA Guidelines, 1980 May
27	11		Research with Recombinant DNA, 1977
27	12		Restriction of Research with Recombinant DNA, 1978 Sep
27	13		Risk Assessment of rDNA Experimentation with Escherichia Coli K12, 1977 Jun 20-21
27	14		Role of Institutional Biosafety Committees, 1987 Dec
27	15		Safety Considerations for Biotechnology, 1992
27	16		SAGENE 1979 Revised Guidelines, 1979 Jul
27	17		Science Policy Implications of DNA Recombinant Molecule Research, 1977 Mar - Sep
27	18		Science Policy Implications of DNA Recombinant Molecule Research, 1978 Mar
27	19		Selective Control of DNA Helix Openings During Gene Regulation, 1976 Feb
27	20		The Social Contract for Science: Congress, the National Institutes of Health, and the Boundary between Politics and Science, 1993 Jun
27	21		Values and the Advance of Medical Science, [ca. 1990]

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Series V: Director, National Institutes of Health, 1962-2001 (bulk 1974-1981)
	The files of the Director, National Institutes of Health Series contain materials related to Fredrickson's tenure as the director of NIH. The series consists of four sub-series covering: office files; the Advisory Committee to the Director; NIH budget authorization; and the Secretary of Health and Human Services. Fredrickson divided his files into topical categories at a later date, possibly to prepare them for inclusion on the Profiles in Science website. Materials in this series include memos, correspondence, notes, meeting minutes, reports, etc.




	These files are not a complete record of the Office of the Director, NIH. They are instead a selection of materials concerning different aspects of Fredrickson's term as Director. Researchers interested in Fredrickson's involvement with rDNA as NIH Director should consult Series IV: Recombinant DNA Materials.




	The files in the Authorization sub-series relate to the Health Research Act of 1980, an attempt by the U.S. Congress to remove Section 301 of the Public Service Act of 1944 for conduct and support of medical research. Section 301 allows for NIH's extramural program of grants and training. Fredrickson and his allies fought against Congress over changes to Section 301, and prevented its passage. Fredrickson claimed the struggle was "the bitterest I experienced in my career" (Quoted from the "Summary" folder, Authorization sub-series, Box 30, Folder 9).




	Most folders have a brief summary of their contents written by Fredrickson in 1988. The materials in the folders remain in their original order, and the folders themselves are organized according to Fredrickson's computer's hard drive filing structure. The folder titles in this sub-series were modified from Fredrickson's hard drive titles, and the original titles are noted on the folders. Materials include reprints, correspondence, memos, notes, newspaper articles, etc. These materials tend not to be original documents, but rather photocopies of the originals, with additional comments by Fredrickson.





Box	Folder
		Office Files, 1974-1989

28	1		Appointment, 1974-1980
28	2		[Nomination], 1975
28	3		Henkin, Robert I., 1975
28	4		Guest Book Signatures, 1975-1981
28	box		Daily Agenda of Appointments, 1975-1981
28	5		Events, 1975-1989
28	6		SEC, 1977-1980
28	7		Responsibilities of NIH, 1977-1979
28	8		National Toxicology Program, 1978
28	9		"Science Deputy" Position, 1978
28	10		NTOXP/GDI, 1978 Mar 5
28	11-12		[Radiation], 1978-1979
28	13		Three Mile Island, 1978-1979
29	1		Three Mile Island (cont'd.), 1978-1979
29	2		Stabilization Institute, 1978-1990
29	3		Federal Committees on Three Mile Island, 1979
29	4		Ethics, 1979
29	5		1982 OMB Briefing Book, 1980
29	6		Consensus Development Conference Summaries, 1980
29	6a		Disbarment Regulations, 1980
29	7-8		1983 Institutes' Preliminary Budgets to NIH, 1981
29	9		Research Plan, 1981
29	10		An Assessment of the Office of Health and Environmental Research, 1981
29	11		1982 House/Senate Briefing Book, 1981
29	12		Small Business Set-Aside Bills, 1981
29	13		Research Manpower, 1981
29	14		Indirect Costs of Health Care, 1981
29	15		1983 PHS Appeals, 1981 Jun 10
29	16		[Resignation], 1981
29	17		Resignation, 1981
29	18		Bulloch et al. vs. USA, Salt Lake Radiation Suit, 1982
29	19		Transcript of the Meeting of Subcommittee 3 (The Forum), 1982 Jan 29
29	20		Congressional Relations, 1988
29	21		[Hans Stetten's Resignation], [n.d.]
29	22		Testimony, [n.d.]
		Advisory Committee to the Director, 1980-1981

30	1-2		41st Meeting, DAC, 1980 Oct 20-21
30	3-4		42nd Meeting, DAC, 1981 Mar 16-17
30	5-6		43rd Meeting, DAC, 1981 Jun 8-9
30	7		DAC Working Groups on Costs of Biomedical Research and Cooperative Research Relationships with Industry, 1981 Jun 9
30	8		3rd Meeting, DAC Working Group on Cooperative Research Relationships with Industry, 1981 Jul 30-31
		Authorization, 1962-2001

30	9		Summary, 1980-2001
30	10		ABC, 1978-1991
30	11		DSF Notes, 1962-1988
30	12		Bulwinkle, Alfred Lee, 1950-1971
30	13		Kennedy, Edward M., 1977
30	14		Legislative History of NIH, 1930-1950
30	15		Public Health Service Act History, 1943-1944
30	16		Evolution of Public Health Service Act, 1944-1988
30	17		Public Health Service Act 1940s, 1946-1948
30	18		Public Health Service Act 1950s, 1950-1957
30	19		Public Health Service Act 1960s, 1960-1969
30	20-21		Public Health Service Act 1970s, 1971-1978
30	22		Public Health Service Act 1980s, 1980-1985
30	23		Green Diary 3 Entries, 1980 Feb-May
30	24		Green Diary 5 Entries, 1980 May-Oct
30	25		Green Diary 7 Entries, 1980 Oct-Dec
30	26		Bills - Summary, 1979-1988
31	1		Bills - Health Research Act of 1980, 1980
31	2		Bills - H.R. 6902, 1980 Mar 24
31	3		Bills - H.R. 7036, 1980 Apr 20
31	4		Bills - H.R. 7036, as marked-up 5/11, 1980 May 1
31	5		Bills - S. 988, 1979 Apr 23
31	6		Bills - Zimmerman Bill, 1980-1988
31	7		Bills - Critiques, 1980-1988
31	8		Legislation Hearings, 1980-1988
31	9		Lobbyists, 1980-1988
31	10		Bill Mark-ups, 1980-1988
31	11		Administration Position, 1980-1988
31	12		Outcome of Legislation, 1980-1988
31	13		[Loose Files], 1982-1996
31	14		NIH Authorization Act, S. 2889, 1988 Jan 25
31	15		NIH Revitalization Act of 1993, 1993
		Secretary of Health and Human Services, 1976-1995

31	17		Califano - Advent, 1976-1978
31	18		Califano - Congress, 1978
31	19		Califano - Exit, 1979-1995
31	20		Harris - Advent, 1979
31	21		Harris - Exit, 1980-1981
31	22		Acting Secretary, 1981
31	23		Actions as Acting Secretary, 1981
31	24		Schweiker - Advent, 1981
31	16		General, 1988

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Series VI: Reports and Committees, 1970-1991
	The Reports and Committees Series includes reports, notes, and correspondence relating to Fredrickson's work on various committees throughout his career. The series is divided into five sub-series according to the committee. Reprints have not been removed from this Series as they directly relate to the committee reports and meetings. Fredrickson himself separated these committees from his "professional activities" grouping in his original arrangement. It is assumed that he felt these committees were important enough to his career that they warrant their own series. The sub-series are arranged chronologically.




	The Interagency Task Force on Ionizing Radiation and the Committee on Federal Research into the Biological Effects of Ionizing Radiation (FREIR) sub-series includes reports of the committees, research compilations, and transcripts of Congressional hearings related to the committee's work.




	On March 28, 1979, the threat of a breakdown at the nuclear reactor at Three Mile Island, Pennsylvania initiated a number of committees and other responsibilities involving the director of NIH. Fredrickson, as NIH Director, served as the Chairman of FREIR, which was chartered on June 18, 1979. The Interagency Task Force on Ionizing Radiation had released two reports on the subject, one in February followed by a second in April 1979.




	The White House Science Council, Federal Laboratory Review Panel sub-series includes pamphlets and articles, research reprints, supporting documentation, correspondence, notes on site visits, draft reports, itineraries, etc. relating to Fredrickson's work as a member of the Federal Laboratory Review Panel of the White House Science Council. The Panel's mission was to inspect federal research laboratories, and offer recommendations on how efficiency could be improved. The Panel visited a number of laboratories, and there is extensive material on the facilities at Argonne, Los Alamos, and Oak Ridge, as well as the Naval Research Laboratory. The Office of Science and Technology Policy, Executive Office of the President (OSTP), and the Energy Research Advisory Board, Department of Energy (ERAB) all assisted the Panel.




Box	Folder
		National Heart and Lung Institute Panel on Hyperlipidemia and Premature Atherosclerosis, 1970

31	25		NHI-RC Formation, 1970 Report, 1970 Jun 12-13
		Task Force on Genetic Factors in Atherosclerotic Disease, National Heart and Lung Institute, 1974-1975

31	26		Report from the National Heart and Lung Institute, 1974-1975
		Interagency Task Force on Ionizing Radiation and the Committee on Federal Research into the Biological Effects of Ionizing Radiation, 1978-1981

31	28		Effect of Radiation on Human Health, Vol. 2, 1978 Jul 11-14
31	29		Effects of Nuclear Weapons Testing on Health, Vol. 1, 1979
32	1-2		Effects of Nuclear Weapons Testing on Health, Vol. 2-3, 1979
32	3		Low-Level Radiation Effects on Health, 1979, Apr 23, May 24, Aug 1
32	4		Public Comments on the Work Group Reports, 1979 Jun
32	5		Report of the Work Group on Care and Benefits, 1979 Jun
32	6		Report of the Work Group on Exposure Reduction, 1979 Jun
32	7		Report of the Work Group on Institutional Arrangements, 1979 Jun
32	8		Report of the Work Group on Public Information, 1979 Jun
32	9		Report of the Work Group on Records and Privacy, 1979 Jun
32	10		Report of the Work Group on Science, 1979 Jun
32	11		Biological Effects of Ionizing Radiation, 1979 Aug
32	12		Biological Effects of Ionizing Radiation, Appendix I, Vol. 1, 1979 Aug
32	13		Biological Effects of Ionizing Radiation, Appendix I, Vol. 2, 1979 Aug
32	14		Biological Effects of Ionizing Radiation, Appendices II and III, 1979 Aug
32	15		Follow-up Studies on Biological and Health Effects Resulting from the Three Mile Island Nuclear Power Plant Accident, 1979 Aug
32	16		Report of the President's Commission on the Accident at Three Mile Island, 1979 Oct
32	17		Report on a Proposal to Create a Tri-state Commission to Study Possible Health Effects of Radiation from Nuclear Weapons Testing, 1979 Nov
32	18		To Address a Proposed Federal Radiation Research Agenda, Vol. 1, 1980 Mar 10-11
33	1		To Address a Proposed Federal Radiation Research Agenda, Vol. 2, 1980 Mar 10-11
33	2-3		Research on the Health Effects of Radiation, Vol. 1, Part A-B, 1980 Sep
33	4		Consideration of Three Proposals to Conduct Research on Possible Health Effects of Radiation from Nuclear Weapons Testing in Arizona, Nevada, and Utah and Nuclear Weapon Testing and Studies Related to Health Effects: A Historical Summary, 1980 Oct
33	5		Problems in Assessing the Cancer Risks of Low-Level Ionizing Radiation Exposure, Vol. 2, 1981 Jan
33	6		Federal Strategy for Research into the Biological Effects of Ionizing Radiation, 1981 Jun
33	7		The FREIR Report, 1981
31	27		Radiation-Related Documents, [ca. 1990s]
		White House Science Council, Federal Laboratory Review Panel, 1980-1984

33	8-10		Federal Labs Panel, 1981-1982
33	11		FLP General, 1982
34	1		FLP General (cont'd.), 1982
34	2		Draft Report, 1982
34	3		Progress Report on Implementing the Recommendations of the WSHC's Federal Laboratory Review Panel, 1984 Jul
34	4		Argonne, 1981-1982
34	5		Argonne National Laboratory Institutional Plan FY1982-FY1987, 1981 Nov
34	6		Beltsville Agricultural Research Center, 1982
34	7		Brookhaven Lab, 1982
34	8-9		DOD Laboratories, 1981-1982
34	10-11		Department of Energy Site Visits Material, 1981-1983
34	12		Hanford, 1982
34	13		Inhalation Toxicology Research Institute, 1982
34	14		Jet Propulsion Laboratories, 1982
34	15-16		Lawrence Berkeley Laboratory, 1981-1982
35	1-5		Los Alamos, 1980-1982
35	5		National Bureau of Standards, 1982
35	6		The National Laboratories: Their Evolution, 1987 May 2
35	7-9		Naval Research Laboratory, 1981-1982
35	10-12		Oak Ridge, 1982
35	13		OSTP, 1982-1988
35	14		Sandia, 1982
		Evaluation of the Fourth Medical and Health Research Programme, 1987-1991

35	15-16		Comité Consultif National D'Ethique, 1984-1991
36	1		Official Journal of the European Communities, 1987-1990
36	2-5		Annex 1-4, 1987-1991
36	6		Objectives and Scientific Content, 1987-1991
36	7		MHR4 Research Targets, Outlines #18-25, 1987-1991
36	8		MHR4 Target Data, 1988
36	9-10		MHR4 Evaluation, 1988-1991
36	11		Questionnaire, 1989-1990
36	12		EC Supplementary, 1990
36	13		Europe Report, 1990
36	14		Laredo and Akehurst, 1990
36	15		Maynard, Alan, 1990
36	16		Sample Contracts, 1990
36	17		Proposal to Consult for the European Community, 1990 Feb 7
36	18		EC Visit March 21/23, 1990 Mar
36	19		Bibliometric Study for the Evaluation of the European Communities' Programme on Medical and Health Research, 1990 May
36	20		EC - Brussels, 1990 May 7
36	21		EC/AKM, 1990 May 7-11
36	22		Evaluation of the Fourth Medical and Health Research Programme, 1987-1991, 1990 Jul
36	23		Dresden, 1997
36	24		Biometric Study, [n.d.]

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Series VII: Travel, 1961-1997
	The Travel Series contains materials related to Fredrickson's travels both in an official capacity for the National Institutes of Health, and on his own as a lecturer, speaker, or consultant. Most of the trips were to attend conferences or give lectures, while a few were to collect awards. Fredrickson provided summaries of many of the longer trips. A majority of the papers consist of correspondence between Fredrickson and his hosts, usually to discuss travel arrangements or lecture topics. Other items include lecture notes, program books, and a few newspaper clippings.




	Noteworthy trips include: the U.S.S.R. (1963 and 1973); New Zealand, Thailand, Nepal, and India (1971); and China (1978). There are travel journals from the 1963 U.S.S.R. and 1978 China trips.




Box	Folder
36	25	Calendar, Date Sorted, 1961-1997
36	26-28	Russia, 1963 Sep 21 - Oct 16, 1963-1984
36	29	Russia, 1963 Sep 21 - Oct 16, Diary, 1963
36	30	Russia, 1963 Sep 21 - Oct 16, Memorabilia, 1963
36	31	Europe, 1965 Apr 28 - May 2, 1964-1965
36	32	Switzerland, 1964 Jun, 1964 Jun
36	33	Milan, 1965 Sep 13-15, 1964-1965
36	34	England, 1966 Mar 17-19, 1966
36	35	Athens, 1966 May 30 - Jun 3, 1966
36	36	Beirut and Israel, 1967 May 11-14, 1967
36	37	Portugal, 1967 Jul 12-15, 1967
36	38	Montreal, 1967 Aug 31 - Sep 1, 1966-1967
36	39	Como, Italy, 1967 Oct 11-14, 1967
36	40	London, 1967 Dec 7-10, 1967
37	1-2	1968 Travels, 1968
37	3	1969 Travels, 1969
37	4	1970 Travels, 1969-1970
37	5	1971 Travels, 1971 Feb - Aug
37	6	New Zealand, 1971 Sep 10 - Oct 9 and Thailand, Nepal, and India, 1971 Oct, Journal, 1971 Sep 10 - Oct 18
37	7-9	New Zealand, 1971 Sep 10 - Oct 9 and Thailand, Nepal, and India, 1971 Oct, 1971 Aug - Nov
37	10	1972 Travel, 1972 Mar - Sep
37	11	China, 1972 Oct 13-14, 1972 Oct
37	12-13	Russian Exchange, 1972-1973
37	14	USSR, 1973 Mar 18-25, 1973
37	15	USSR-US Joint Committee Meeting, 1973 Mar
37	16	Report of USSR Trip, 1973
37	17-18	1974 Travel, 1974 Jan - Mar
		China [Science and Technology sharing], 1978 July

37	19		China 1978, remembrances, 1998
37	20-21		Briefing materials
37	22		Banquet
37	23		Journal
38	1		Medical information exchange
38	2		U.S. delegation and Chinese participants [list]
38	3		Visit to counterpart institutions--Fu Wai Hospital, Inst. Materia Medica
38	4		Medicine/biomedical research discussion
38	5		Summary of conversation with counterpart group
38	6		Politburo of the Chinese Communist Party
38	7		Peking general information/background
38	8		Thank-You Notes, 1978 Aug - Sep
38	9		U.S. Delegation to the People's Republic of China Photos [2], 1978
38	10		Reference Notes, 1977 Sep - 1978 Jul
38	11	1978-1979 Travel, 1978 May - 1980 May
38	12-14	1980 Travel, 1979-1980
38	15-17	1981 Travel, 1981
38	18	IRRC Meeting, 1981 Aug 6
38	19	Meeting with Hanna Gray, 1981 Sep 17
38	20	COGENE Symposium, Rome, 1981 Sep 20-23
38	21	Burke Zimmerman's Class, 1981 Sep 23
38	22	Groundbreaking, University of Michigan, 1981 Oct 15
38	23	IOM Presentation: NIH: Autumn or Spring?, 1981 Oct 19
38	24	Columbia University, 1981 Oct 20
38	25	Genentech, San Francisco, 1981 Oct 22
38	26	Dedication of ACRF Building, Bethesda, MD, 1981 Oct 22
38	27	President's Budget Conference, 1981 Oct 26-27
38	28	Foundation Cardiologique, Brussels, 1981 Oct 28
38	29	NAE Annual Meeting, Washington, DC, 1981 Nov 4-5
38	30	Honorary Degree, Albert Einstein College of Yeshiva University, New York City, 1981 Nov 8
38	31	Smithsonian Symposium, Washington, DC, 1981 Nov 9
38	32	University of California, Santa Barbara, 1981 Nov 11-13
38	33	Ad Hoc Seminar, Century Association, New York, 1981 Nov 19
38	34	GURSS Forum, 1981 Nov 20
38	35	NAS/NRC Organization Review, 1981 Nov 30
38	36	Research Seminar in Health Policy, Harvard University, 1981 Dec 2
38	37	Sarah Poiley Award, New York Academy of Science, 1981 Dec 3
38	38	AAAS Public Lecture - Science and the Culture Warp, 1982 Jan 7
38	39	Providence, RI, 1982 Feb 1
38	40	John Gardner, 1982 Feb 3
38	41	Ad Hoc Committee on Agricultural Science, 1982 Feb 11
38	42	University of Georgia, 1982 Feb 12
38	43	External Advisory Committee, Dallas, TX, 1982 Feb 16-18
38	44	COSEPUP Meeting, GURSS Presentation, 1982 Feb 22
38	45	DOD Forum Meeting, 1982 Feb 24
38	46	Baylor University, Houston, 1982 Mar 3
38	47	University of Texas Science Center, Houston - Visiting Committee, 1982 Mar 4-5
38	48	Duke University Round Table Meeting on Science, Durham, NC, 1982 Mar 17-18
38	49	Potter Lecture, Philadelphia, PA, 1982 Apr 7
38	50	Fox Chase Cancer Center, Philadelphia, PA, 1982 Apr 8
38	51	New York University, 1982 Apr 14-15
38	52	Mt. Sinai, New York City, 1982 Apr 14
38	53	Sloan-Kettering Cancer Center, New York City, 1982 Apr 15
38	54	Wiesbaden, West Germany, 1982 Apr 17-21
38	55	Lilly Lecture, London, England, 1982 Apr 25-30
39	1	NAS Annual Meeting, 1982 Apr 25-28
39	2	Association of American Physicians, Shoreham-DC, 1982 May 7-10
39	3	Thorn Lecture, Harvard University, 1982 May 21
39	4	Rockefeller Archive Center - Invitation, 1982 May 25-27
39	5	University of Medicine and Dentistry of New Jersey - Honorary Degree, 1982 May 26
39	6	Cornell University Medical School Commencement, 1982 May 26
39	7	Keenan Convention, Chapel Hill, NC, 1982 Jun 2-5
39	8	OSTP Meeting / Agricultural Research, Morrilton, AR, 1982 Jun 14-15
39	9	Federal Executive Institute Meeting, Fort McNair, 1982 Jun 29
39	10	National Science Board, 1982 Jul 9-10
39	11	Universal Foods Executive Seminar, Milwaukee, WI, 1982 Jul 12
39	12	Penn State Board of Trustees, 1982 Jul 19
39	13	Cornell Medical College Medical Advisory Committee, 1982 Jul 28
39	14	Whitehead / HHMI / MIT, Boston, MA, 1982 Aug 25
39	15	Society of Research Administrators, Atlanta, GA, 1982 Sep 13
39	16	MIT, Boston, MA, 1982 Oct 14
39	17	DOD / University Forum Meeting, 1982 Oct 26
39	18	NAS Consortium Foundation, Washington, DC, 1982 Oct 27
39	19	University of Michigan Clinical Center Anniversary Celebration, 1982 Oct 29
39	20	University of Alabama Advisory Committee, Birmingham, AL, 1982 Nov 9-11
39	21	NIEHS Dedication, Chapel Hill, NC, 1982 Nov 15
39	22	Whitehead Institute, Boston, MA, 1982 Nov 19
39	23	Scripps Clinic Scientific Review Committee, La Jolla, CA, 1983 Jan 10-12
39	24	Ad Hoc Coalition on Medical Research, 1983 Jan 13
39	25	American College of Cardiology, New Orleans, LA, 1983 Mar 23
39	26	Cardiovascular Research Institute, San Francisco, CA, 1983 Oct 19
39	27	Nobel Festival, Stockholm, 1985 Dec
39	28	Nobel Festival, Stockholm - [Newspapers], 1985 Dec
39	29	Nobel Festival, Stockholm - [Memorabilia], 1985 Dec
39	30	Les Droits de L'Homme - NAS - University of Virginia, 1989 Oct 27
39	31	European Community, 1990 Mar - Jun
39	32	Columbia University, 1994
39	33	XIth International Symposium on Atherosclerosis, Paris, 1997

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Series VIII: Professional Activities, 1958-2000
	The files of the Professional Activities Series relate to Fredrickson's activities before and after his tenure as NIH Director. The series is divided into eight sub-series including: the National Heart Institute; the Institute of Medicine; Fredrickson's involvement as medical advisor to King Hassan II of Morocco; the Howard Hughes Medical Institute; the Advisory Committee on NIH; the Foundation for Biomedical Research; his research for his 1993 paper "Biomedical Science and the Culture Warp;" and his study of clinical research.




	Fredrickson began his career at the National Heart Institute (NHI) (later known both as the National Heart and Lung Institute and the National Heart, Lung and Blood Institute) in 1953 as a clinical associate, eventually rising to the ranks of Director of the institute in 1966, and Director of Intramural Research of NHI in 1969.




	The files of the National Heart Institute sub-series relate to Fredrickson's early scientific work at NIH, and include memos, notes, correspondence, and newspaper clippings. The main topics are Fredrickson's research into the typing of abnormalities in blood lipoproteins and Tangier Disease. There is very little primary source material (e.g. lab notebooks) for Fredrickson's research career at NHI. Also included are materials related to Fredrickson's involvement as Director of NHI with the Cardiac Transplantation Meeting held on December 28, 1967 in response to Dr. Christiaan Barnard's groundbreaking attempt to transplant a human heart.




	The Morocco sub-series consists of materials relating to Fredrickson's activities as medical advisor to King Hassan II beginning in 1975 and his election to the Moroccan Academy of Sciences in 1991. Researchers interested in this aspect of Fredrickson's career should also consult the Diaries sub-series of Series I: Personal and Biographical.




	In 1983, Fredrickson became first vice president, then president, CEO and trustee of HHMI. Fredrickson oversaw the sale of the Institute's sole asset, the Hughes Aircraft Company, for six billion dollars, as well as the Institute's subsequent expansion into the largest source of philanthropic support for biomedical research in the United States, dispensing research grants and supporting laboratories in hospitals, educational institutions, and research organizations. Moreover, Fredrickson organized the relocation of the Institute from Coconut Grove, Florida, to Chevy Chase, Maryland.




Box	Folder
		National Heart Institute, 1958-1974

39	34		Cardiac Transplantation Conference, 1958-1969
39	35		Clinical Director, 1966
39	36-37		Typing, 1966-1974
39	38		Tangier Lab Photos, ca. 1960s
39	39		Tangier Correspondence, 1967-1975
39	40		Tangier Reprints, 1968-1975
39	41		Lipid Disorders and Decisions Regarding Therapy, 1970
39	42		Tangier Disease, after 40 years, 1970-1999
39	43		Population Survey, 1970 Nov
39	44		HPL, 1976-1980
39	45		Tangier Disease, 1986 Nov 5
		President, Institute of Medicine, 1971-1997

39	46		[Memoirs], 1971-1990
39	47		Extraordinary Meeting of Council, 1973 Dec 19
39	48		[Acceptance], 1973-1974
39	49		[Reminiscences], 1974-1997
39	50		Presidency Notes, 1997
		Moroccan Activities, 1980-1994

39	51		Academy of Sciences, 1980-1986
39	52		Morocco Diary, 1990 Aug 23
39	53		Rabat, 1994 Nov 28
		President and CEO, Howard Hughes Medical Institute, 1977-1999

39	54		Unscanned [Materials from Profiles in Science], 1977-1987
39	55		HHMI Diary Logs, 1981-1999
39	56		Cloister, 1984
39	57		HHMI Reprise, 1986-1989
39	58		HH Diary, 1986-1998
39	59		Testimony Before Science Policy Task Force, 1986 Apr 23
39	60		Congressional Testimony, Congressman Pepper, 1987 Mar 6
40	1		HHMI Papers, 1988-1999
		NIH Advisory Committee, 1988-1996

40	2		Becker Affair, 1988
40	3		Intramural Clinical Program Retreat, 1989
40	4		NIH Director Searches, 1989-1990
40	5		Meeting, 1990 Jan 29
40	6		Briefing Materials, 1990 Feb 26
40	7		Meeting Minutes, 1990 Apr 25
40	8-9		Healy Period, 1990-1993
40	10		NIH Revitalization Act of 1993, 1992-1993
40	11		Varmus, Harold, 1993-1999
40	12		FY 1997 Appropriation Struggle, 1995-1996
		Foundation for Biomedical Research, 1990

40	13		FBR, 1990
40	14		Memorandum, 1990
40	15		Board of Directors Annual Meeting, 1990 Oct 22
40	16		Research, Animals, and Man, [1990?]
		Culture Warp, 1988-1998

40	17		Story of the NIH Grants, 1988
40	18		Analysis of NIH Intramural Program, 1988-1995
40	19		A Healthy NIH Intramural Program, 1988
40	20		Intramural Research Program Final Draft, 1994
40	21		Implementation and Progress, 1994
40	22		Crisis in Explanations, 1997
40	23		Warp To Do, 1994-1995
40	24		Decline, 1994-1995
40	25		News, 1994-1998
		Clinical Research Study, 1976-2000

40	26		Careers in Clinical Research, 1993
40	27		CLNRES.ASK, 1993
40	28		Clinical Center History, 1976-1999
41	1		Consensus, 1989
41	2		DRG - 50 Years of Peer Review, 1996
41	3		Institute of Medicine Notes, 1984-1993
41	4-6		[Loose Reprints], 1989-2000
41	7		NIH Clinical Center, 1993-1998
41	8		NIH Clinical Research, 1952-1998
41	9		NIH Consensus, 1977-1988
41	10		NIH Division of Research Grants, 1981-1992
41	11		NIH General Clinical Research Centers Program, 1992-1993
41	12		NIH Medical Scientist Training Program, 1993
41	13		NIH Office of Human Subjects Research, 1979-1993
41	14		NIH Peer Review, 1961-1995
41	15		NIH Priority Report, 1998
41	16		Patient-Oriented Research, 1999
41	17		President's Biomedical Research Panel, 1976-1993
41	18-19		Research Training Overview, 1990-1993
41	20		Responsible Conduct in Research, 1988-1995
41	21		Science in the National Interest, 1980-1994
41	22		Third World Clinical Research, 1997-1998

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Series IX: NIH Clinical Center, 1937-1996
	The Clinical Center Series consists of Fredrickson's research as a Scholar-In-Residence at the National Library of Medicine into the origins and history of the Clinical Center of the National Institutes of Health. Materials include letters, interviews, and Fredrickson's notes. Before his death in 2002, Fredrickson gave several presentations on the history of the Clinical Center, but never published a book. Researchers interested in Fredrickson's project should also consult Series XI: Audio-Visual Materials for videotapes of Fredrickson's presentations and the Unpublished sub-series of Series III: Writings for drafts of the presentations.




Box	Folder
42	1-2	General, 1963-1991
42	3	ABC, 1989-1990
42	4	Chronology, 1987-1991
42	5	Appropriations, 1946-1991
42	6	Approval, 1947-1988
42	7	Ambulatory Care and Research Center, 1970-1979
42	8	Early Intramural Staff, 1953-1992
42	9	National Science Foundation, 1954-1993
42	10	1990s Information, 1989-1995
42	11	[Pamphlets], 1987-1993
42	12	[Memorabilia], [n.d.]
42	13	Bullwinkle, Alfred J., 1946-1994
42	14	Ewing, Oscar R., 1990
42	15	Dyer, Rolla Eugene, 1930-1990
42	16	Henschel, Richard, 1987
42	17	Hill, Joseph Lister, 1987-1991
42	18	Hollis, Mark and Sebrill, W. Henry, 1987
42	19	Keefe, Frank Bateman, 1990-1991
42	20	Hilleboe, Herman, 1964-1990
42	21	Lasker, Mary, 1944-1994
42	22-22a	Parran, Thomas, 1946-1991
42	23	Mountin, Joseph M., 1981
42	24	Masur, Jack, 1951-1990
42	25	Randall, Joseph Eugene, 1951
42	26	Richards, A. N., [n.d.]
42	27-28	Shannon, James Augustine, 1964-1994
42	29	Sheele, Leonard A., 1963-1993
42	30	Thompson, Lewis Ryers, 1955-1991
42	31	Topping, Norman, 1956-1990
42	32	Van Slyke, Cassius J., 1989-1991
42	33	Early NIH Staff, 1930-1937
42	34	[Before the Clinical Center], 1930-1991
42	35	Development of a Clinical Research Center, 1937-1948
42	36	Concepts, 1943-1990
42	37	National Advisory Cancer Council, 1937-1977
42	38	Planning, 1947-1990s
42	39	Mental Health, 1937-1990s
42	40	[Clinical Center] Site, 1947-1991
42	41	France, 19th Century, 1979-1985
42	42	The Charité Hospital of Humbodlt University, 1990
42	43	Pasteur Hospital, 1986-1993
42	44	Rockefeller Hospital, 1993
42	45	Chronology, 1947-1991
42	46	Construction Begins, 1947-1988
42	47	Dimensions of Proposal, 1984-1990s
42	48	Scientific Advisory Board, 1935-1991
43	1	Office of Scientific Research and Development, Committee on Medical Research, 1934-1994
43	2	Baldwin, Calvin B., 1937-1961
43	3-4	Operating Principles, 1948-1993
43	5-7	Ethics, 1988-1993
43	8	Rules, 1966-1994
43	9	Peer Review, 1993
43	10	Science to 1950, 1960-1992
43	11	Clinical Investigation to 1950, 1981-1989
43	12	Clinical Investigation post 1950, 1987-1994
43	13	[Outline and Draft], [ca. 1994]
43	14	Research and Development, 1976-1996
43	15-16	NIH Consensus Conferences, 1978-1992
43	17	Office of Scientific Integrity, 1992-1993
43	18	Technical Consensus, 1978-1992
43	19	Working Notes, 1987-1994
43	20	Early NIH, 1944-1992
43	21	SciFraud: Imanishi-Kari, 1991

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Series X: Photographic Materials, 1914-1997





Box	Folder
		Personal Photographs, 1914-1997

43	22		Portrait of Blanche Sharp Fredrickson, 1914
43	23		Intern Class at Peter Bent Brigham Hospital, 1949-1950
43	24		DSF with Post-Doctoral Colleagues, ca. 1965
43	25		Cologne Church Slide?, 1970
43	26		Portrait, 1971
43	27		DSF and Eric Fredrickson at the Nordic Museum in Stockholm, ca. 1972
43	28		Portrait, 1974
43	29		DSF, Family, and Theodore Cooper, [ca. 1975]
43	30		Various Portraits, 1976-1997
43	31		Letter from King Hassan II, 1977
43	32		U.S.S.R., 1977 [?]
43	33		Portrait, 1985
43	34		NAS Keynote Speaker, 1987 Oct
43	35		Visit to Monticello with French Scientists, 1989 Oct
43	36		Sharp Family Photographs, 1989
43	37		DSF's Study, [ca. 1989]
43	38		Childhood Scrapbook Reproductions, [ca. 1997?]
44	1		DSF in Jordan, [n.d.]
44	2		DSF and Madame Fredrickson, [n.d.]
44	3		Family, [n.d.]
44	4		Prints of Framed Objects, [n.d.]
44	5		Unidentified Reception, [n.d.]
		Professional Photographs, 1946-1998

44	6		Clinical Center Research Photos, 1946 - ca. 1967
44	7		Delta-4-Chloestenone, 1953
44	8		NLM Set, [ca. 1960s -1990s]
44	9		DSF's Visit to Tangier Island, [ca. 1963]
44	10		Visit to Relatives of Tangier Disease - Pt. Cecil Norris in KY and Mayo Clinic, [ca. 1963]
44	11		Russian Trip, 1963
44	12		European Trip, 1965
44	13		DSF and Hubert Humphrey, [ca. 1967]
44	14		International Summer School of Pathological Neurochemistry, 1967
44	15		Cardiac Transplantation Conference, 1967 Dec 28
44	16		NIH Scientist Photos, 1969
44	17		Molecular Disease Branch, 1971
44	18		NHLBI Branch Chiefs, 1971
44	19		27th Brazilian Congress of Cardiology, 1971 Jul 10-18
44	20		Rep. James Symington Visit, 1973
44	21		USSR Trip, 1973 Mar 18-25
44	22		VI Jiménez Díaz Memorial Lecture, 1974 Jul 4
44	23		Institute of Medicine Photos, 1975
44	24		Fall Guy Lecture, 1975
44	25-26		NIH Director Inauguration, 1975
44	27-28		NIH Alumni Reunion, 1975
44	29		NIH Director Photographs, 1976-1981
44	30		Senator J. Glenn Beall, Jr. Visit, 1976 Feb 2
44	31		Joseph A. Califano Visit, 1977
44	32		Carter / Callaghan Visit, 1977
44	33		NIH Director Reappointment, 1977
44	34		Xavier University of Louisiana MBS Banquet, 1977
44	35		Meeting to Find Successor to Hans Stetten, Deputy Director (Science), 1978
44	36		rDNA Photos, 1978
44	37		[First Institute Relay], 1978
44	38		Prince and Princess Hitachi Visit, ca. 1978
44	39		Senate Appropriations Committee Hearing, 1978 Feb-Mar
44	40		1978 China Trip - Contact Sheets, 1978 Jul
44	41-42		1978 China Trip, 1978 Jul
44	43		DSF and Seymour Perry, 1978 Sep
44	44		Joseph A. Califano Visit, 1979 Mar 8
44	45		Patricia Roberts Harris Visit, 1979 Sep 12
44	46		Purkyne Medal, 1980 Feb 10
44	47		King Baudouin and Queen Fabiola of Belgium Visit, 1980 Apr 22
44	48		Mount St. Helens Trip, 1980 May 22
44	49		Vincent T. DeVita, NCI Director, Swearing-In Ceremony, 1980 Aug 8
44	50		12th Annual Honor Awards Ceremony, 1980 Dec 1
44	51		Richard S. Schweiker Visit, ca. 1981
44	52		Koop, C. Everett, 1981
44	53		Nairobi Photos, 1981
44	54		NIH Discussion, 1981
44	55-56		NIH Farewell Party, 1981 Jun 30
44	57		Beltsville Agricultural Research Center, 1982 Oct 8
45	1		Nobel Ceremony, 1985
45	2		HHMI, 1984-1986
45	3		Sackler Award, 1986
45	4		Friends of NLM Patron Dinner, 1988 Dec
45	5		Ronald Reagan / White House Science Council, 1989
45	6		Les Droits de L'Homme Symposium, 1989 Oct 27
45	7		Clinical Center Research Slides, 1990
45	8		Catalog, 1990 Feb 6
45	9		Sandoz Award, 1991
45	10		Hassan II, 1994
45	11		Morocco Meeting, 1998 May 5-7
45	12		Awards, [n.d.]
45	13		[Cholesterol Cartoon], [n.d.]
45	14		Christian Anfinsen, [n.d.]
45	15		[Dr. Lowe], [n.d.]
45	16		Fondazione Carlo Erba, [n.d.]
45	17		Groups, [n.d.]
45	18		Jim Dixon, [n.d.]
45	19		Unidentified Groundbreaking, [n.d.]
45	20		Unknown, [n.d.]
45	21		Unknown Banquet, [n.d.]
45	22		rDNA Materials, [n.d.]
		Lab Photographs, 1959-1967

OS3	9		[Tangier Tonsils], 1959
45	23		Tangier Disease Tonsils, 1960
45	24-26		Tangier Disease [includes 2 folders of negatives], [ca. 1960s]
45	27		Tangier Disease Lantern Slide, [n.d.]
45	28		Russia, 1963
45	29		England, 1966
45	30		1967 Beirut Trip, 1967
45	31		Familial Hyperlipoproteinemia, [n.d.]
45	32		National Heart Institute - Molecular Disease Branch, [n.d.]
45	33		Unknown, [n.d.]
OS3	10		NHLI-MDB, [n.d.]

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Series XI: Audio-Visual Materials, 1978-1997





Box	Folder
		Video, 1978-1997

46			House Call with Dr. Timothy Johnson, [3/4 inch tape], 1978 Mar
46			House Call with Dr. Timothy Johnson, [VHS], 1978 Mar
46			Compilation Tape: 1) Dr Marshall Nirenberg Nobel Award -NIH; 2) House Call; 3) Ben Wattenberg at Large, [Beta], [1978-1985?]
46			NIH Director's Award Ceremony, [3/4 inch tape], 1980 Dec 1
46			NIH Director's Award Ceremony, [VHS], 1980 Dec 1
46			Dr. Donald Fredrickson at the National Institutes of Health, [VHS], 1981
46			[Compilation] Director's Award 1981 and Resignation 1981 Jun 19, [Beta], 1981
46			[Compilation] Director's Award 1981 and Resignation 1981 Jun 19, [VHS], 1981
46			Shannon Bust Ceremony Tape, [Beta], 1984 Mar 23
46			Howard Hughes Medical Institute/NIH Video News Release, [Beta], 1985 Oct 1
46			Ben Wattenberg at Large, [3/4 inch tape], [1985?] Oct 23
46			Dr. Fredrickson's Interview with Dr. Green, [Beta], 1987 Mar 27
46			Clinical Center: The Beginnings, [3/4 inch tape], 1991 Feb 7
46			Clinical Center: The Beginnings, [VHS "non-audio"], 1991 Feb 7
46			Clinical Center: The Beginnings, [VHS], 1991 Apr 11
46			Clinical Center: The Beginnings, [VHS], 1991 Apr 11
46			NIH: The Crucible Years (1930-1948), [VHS], 1991 May 6
46			NIH: The Crucible Years (1930-1948), [3/4 inch tape], 1993 Jul 2
46			NIH: The Crucible Years (1930-1948), [VHS], 1993 Jul 2
46			The ABRI - Institute Coalition, [VHS], [n.d.]
46			Clinical Center 40th Anniversary, [VHS], [n.d.]
46			The Health Century - 4th of 4 Molecular Biology for NIH Centennial, [Beta], [n.d.]
46			Who Lives, Who Dies, Who Decides? Panel #1 Introduction and Technology, [VHS], [n.d.]
46			Who Lives, Who Dies, Who Decides? Panel #2 Resource Allocation, [VHS], [n.d.]
46			Who Lives, Who Dies, Who Decides? Panel #3 Quality of Life/Who Decides?, [VHS], [n.d.]
		Audio Tapes, 1982-1997

46			Easton Talks, Tapes #1 and #2, [n.d.]
46			Los Alamos Presentation, 1982 Jul 21
46			[Fredrickson on the Recombinant DNA Controversy], [1997?] Apr 17
46			Interview with Donald S. Fredrickson tapes [5 tapes], 1997 May 21
46			Recording of Dr. Fredrickson reading "The Moral", 1997 Jul 14

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Last reviewed: 04 January 2008
Last updated: 05 March 2007
First published: 16 May 2003
Metadata| Permanence level: Permanent: Dynamic Content

Finding Aid to the Donald S. Fredrickson Papers, 1910-2002 (bulk 1960-1999)

TABLE OF CONTENTS

Brief Chronology

Awards and Prizes

Editorial Appointments

Honorary Degrees

Lectureships

Memberships

Restrictions

Restrictions

Copyright

Series I: Personal and Biographical, 1914-2002 (bulk 1960-1990)

Series II: Correspondence, 1948-1998

Series III: Writings, 1910-2001

Series IV: Recombinant DNA Materials, 1947-2001 (bulk 1974-1989)

Series V: Director, National Institutes of Health, 1962-2001 (bulk 1974-1981)

Series VI: Reports and Committees, 1970-1991

Series VII: Travel, 1961-1997

Series VIII: Professional Activities, 1958-2000

Series IX: NIH Clinical Center, 1937-1996

Series X: Photographic Materials, 1914-1997

Series XI: Audio-Visual Materials, 1978-1997