Selected Publications

Renal Pharmacology Group

1. Kimura, T., Perry, J., Anzai, N., Pritchard, J.B., Moaddel, R.: Development and characterization of immobilized human organic anion transporter-based liquid chromatographic stationary phase: hOAT1 and hOAT2. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 859(2): 267-271, 2007. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17977807)
2. Perry, J.L., Dembla-Rajpal, N., Hall, L.A., Pritchard, J.B.: A thrree-dimensional model of human organic anion transporter 1: Aromatic amino acids required for substrate transport. J. Biol. Chem. 281: 38071-9, 2006.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17038320)
3. Aslamkhan*, A.G., Thompson*, D.M., Perry, J.L., Bleasby, K., Wolff, N., Barros, S., Miller, D.S., and Pritchard, J.B.: The flounder organic anion transporter (fOat) has sequence, function, and substrate specificity similarity to both mammalian OATs 1 and 3. Am. J. Physiol. 291(6):R1773-80, 2006.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16857889)
4. Bow, D.A.J., Perry, J.L., Simon, J.D., and Pritchard, J.B.: The impact of plasma protein binding on the renal transport of organic anions. J. Pharmacol. Exptl. Ther. 316: 349-355, 2006.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16195420)
5. Bleasby, K., Hall, L.A., Mohrenweiser, H.W., and Pritchard, J.B.: Functional consequences of single nucleotide polymorphisms in the human organic anion transporter hOAT1 (SLC22A6). J. Pharmacol. Exptl. Ther. 314: 923-31, 2005.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15914676)
6. Sykes, D., Sweet, D.H., Lowes, S., Nigam, S.K., Pritchard, J.B., and Miller, D.S.: Organic anion transport in choroid plexus from wild-type and organic anion transporter 3 (Slc22a8)-null mice. Am. J. Physiol. Renal Physiol. 286: F972-F978, 2004.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15075193)
7. Sweet, D.H., Chan, L.M.S., Walden, R., Yang, X-P., Miller, D.S., and Pritchard, J.B. Organic anion transporter 3 (OAT3 [SLC22a8]) is a dicarboxylate exchanger indirectly coupled to the sodium gradient. Am. J. Physiol. Renal Physiol. 284: F763-F769, 2003.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12488248)
8. Sweet, D.H., Miller, D.S., Pritchard, J.B., Magner, F., Fujiwara, Beier, D.R., and Nigam, S.K. Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (OAT3 [SLC22a8]) knockout mice. J. Biol. Chem. 277: 26934-26943, 2002.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12011098)
9. Pritchard, J.B., Sweet, D.H., Miller, D.S., and Walden, R.: Mechanism of organic anion transport across the apical membrane of choroid plexus. J. Biol. Chem. 274: 33382-33387, 1999.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10559217)
10. Sweet, D.H., Wolff, N.A., and Pritchard, J.B.: Expression cloning and characterization of ROAT1, a novel organic anion transporter from rat kideny. J. Biol. Chem. 272: 30088-30095, 1997.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9374486)
11. Villalobos, A.R., Parmelee, J.T., and Pritchard, J.B.: Functional characterization choroid plexus epithelial cells in primary culture. J. Pharmacol. Exp. Ther. 282: 1109-1116, 1997.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9262381)
12. Pritchard, J.B.: Intracellular a-ketoglutarate controls the efficacy of renal organic anion transport. J. Pharmacol. Exp.Ther. 274: 1278-1284, 1995.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=7562499)
13. Pritchard, J.B., Sykes, D.B., Walden, R., and Miller, D.S.: ATP-dependent transport of tetraethylammonium by endosomes isolated from rat renal cortex. Amer. J. Physiol. 266: F966-F976, 1994.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8023976)
14. Pritchard, J.B.: Coupled transport of p-aminohippurate by rat basolateral membrane vesicles. Amer. J. Physiol. 255: F597-F604, 1988.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=3177651)
15. Pritchard, J.B.: Accumulation of anionic pesticides by rabbit choroid plexus in vitro. J. Pharmacol. Exp. Ther. 212: 354-359, 1980.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=7351648)
16. Bow DAJ, Perry JL, Miller DS, Pritchard JB, Brouwer KLR.: Localization of P-gp (Abcb1) and Mrp2 (Abcc2) in freshly isolated rat hepatocytes. Drug Metab Dispos. 36: 198-202, 2008. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17954525)