Cellular Neurobiology Research Branch
Overview
The Cellular Neurobiology Branch studies CNS function at the cellular level, including physiological properties of cells, biochemical mechanisms and pathways, effects of neurotrophic factors, neuroanatomical methods, electrophysiology, animal models of drug effects and neurodegeneration, and drug effects on human cells.
Areas of Research
- Cellular Neurobiology
- Neuroplasticity
- Cellular Signaling pathways related to drugs of abuse.
- Cellular models for studies of drug abuse.
- Electrophysiological effects of drugs of abuse.
- Neuroanatomical basis of drug effects, drug abuse, and addiction
- Changes in gene transcription and protein expression in drug abuse
- Brain function, and neural transplantation and repair techniques
- Development of cellular models and in vitro generation of neurons
- Neurochemical analysis of proteins and lipids
- Models of neuropsychiatric disorders and development of therapeutic techniques
Future Directions
The focus of the branch is expected to be on neuroplasticity and the neurobiological adaptations which underlie drug abuse and addiction.
Branch Chief: William J. Freed, Ph.D.
Section Chiefs: William J. Freed, Ph.D., Barry Hoffer, M.D., Ph.D.
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Cellular Neurobiology Research Branch
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