Basic Research to Therapeutic Applications
Lawrence H. Lazarus, Ph.D.
Tel (919) 541-3238
Fax (919) 541-5737
Curriculum Vitae (http://www.niehs.nih.gov/research/atniehs/labs/lpc/mc/docs/Lazarus_CV.pdf) P.O. Box 12233
Mail Drop C3-04
Research Triangle Park, North Carolina 27709
The Medicinal Chemistry Group is a leading research program aimed at the development of unique opioid receptor compounds. The long term objective is to translate basic research into clinical and therapeutic applications, such as non-addictive analgesics for relief from chronic and acute pain stemming from trauma, cancer, or surgery, and antagonists to modulate neural reward mechanisms dealing with addiction to opiate drugs, alcohol and food.
The Medicinal Chemistry Group is a constituent member of the Laboratory of Pharmacology whose mission is the combined development of laboratory methods for humans and animals with computational, statistical, and mathematical methods to further the understanding of the mechanisms underlying environmental disease and to provide the linkage between "cutting edge" research in environmental health and the evaluation of health risks from environmental exposures.
The programs in the Medicinal Chemistry Group form an integrated and systematic three-prong approach (see current projects). Lawrence H. Lazarus, Ph.D., and Sharon D. Bryant, computational chemist, are recognized amongst their peers for their discoveries in the field of Medicinal Chemistry Group and molecular modeling.
Major areas of research
For biographical information on Lawrence H. Lazarus, Ph.D., please see his Curriculum Vitae.