Science News
about Bipolar Disorder
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- Fear Circuit Flares as Bipolar Youth Misread Faces
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May 29, 2006
Press Release
Youth with bipolar disorder misread facial expressions as hostile and show heightened neural reactions when they focus on emotional aspects of neutral faces, NIMH researchers have discovered.
- Lithium Blocks Enzyme To Help Cells’ Clocks Keep On Tickin’
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February 17, 2006
Science Update
NIMH-funded researchers have discovered how lithium likely fixes body clocks gone awry, stabilizing sleep-wake cycles and other daily rhythms disturbed along with mood in bipolar disorder.
- Largest Study to Date on Pediatric Bipolar Disorder Describes Disease Characteristics And Short-Term Outcomes
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February 8, 2006
Science Update
Recent findings from the multi-site, NIMH-funded Course and Outcome of Bipolar Illness in Youth (COBY) study are helping to shape the understanding of three major subtypes of bipolar disorder that affect children and adolescents and how this diagnosis may affect them as adults.
- Early Findings from Largest NIMH-Funded Research Program on Bipolar Disorder Begin to Build Evidence-Base on Best Treatment Options
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February 1, 2006
Science Update
Findings from an NIMH research program on bipolar disorder provide much needed long-term data on the chronic, recurrent course of the disorder, and begin the work of building an evidence-base on the best treatments for those with the disorder.
- Mutant Gene Linked to Treatment-Resistant Depression
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December 13, 2004
Science Update
A mutant gene that starves the brain of serotonin, a mood-regulating chemical messenger, has been discovered and found to be 10 times more prevalent in depressed patients than in control subjects, report researchers funded by the National Institutes of Health’s National Institute of Mental Health (NIMH) and National Heart Lung and Blood Institute (NHLBI).
- Stress Impairs Thinking Via Mania-Linked Enzyme
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October 29, 2004
Press Release
An errant enzyme linked to bipolar disorder, in the brain’s prefrontal cortex, impairs cognition under stress, an animal study shows.
- Mental Illness Genetics Among Science’s Top “Breakthroughs“ for 2003
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December 22, 2003
Press Release
Research on the genetics of mental illness, most of it NIMH-funded and much of it in the Institute’s own laboratories, was named the #2 scientific "breakthrough of the year" by Science magazine in its December l9, 2003, issue.
- NIMH Awards $22.6 Million for Center for Collaborative Research on Mental Disorders
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July 1, 2003
Press Release
Under a cooperative agreement, the Center will accelerate progress toward understanding genetic origins of mental disorders including autism, schizophrenia, bipolar disorder, and depression.
- Lithium Shows Promise Against Alzheimer’s in Mouse Model
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May 21, 2003
Press Release
An enzyme crucial to formation of Alzheimer’s plaques and tangles may hold promise as a target for future medications, suggest studies in mice and cells.
- NIMH Awards Howard University $6.5 Million
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January 25, 2002
Press Release
Howard University Hospital Department of Psychiatry in the College of Medicine (HUCM) has been awarded $6.5 million from the National Institute of Mental Health (NIMH) for a five-year project to implement and develop research studies pertaining to mood and anxiety disorders.