Science News
about Bipolar Disorder
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- Bipolar Disorder Phenome Database May Aid Search for Related Genes
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October 2, 2007
Science Update
Early findings from the recently launched Bipolar Disorder Phenome Database were published in the August 2007 issue of the American Journal of Psychiatry.
- Manic Phase of Bipolar Disorder Benefits from Breast Cancer Medication
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September 12, 2007
Press Release
The medication tamoxifen, best known as a treatment for breast cancer, dramatically reduces symptoms of the manic phase of bipolar disorder more quickly than many standard medications for the mental illness, a new study shows.
- Rates of Bipolar Diagnosis in Youth Rapidly Climbing, Treatment Patterns Similar to Adults
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September 3, 2007
Press Release
The number of visits to a doctor's office that resulted in a diagnosis of bipolar disorder in children and adolescents has increased by 40 times over the last decade, reported researchers funded in part by the National Institutes of Health (NIH).
- Studies Refine Understanding of Treatments for Bipolar Disorder
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September 1, 2007
Science Update
Two new studies provide additional details on best practices for treating people with bipolar disorder, a sometimes debilitating illness marked by severe mood swings between depression and mania. The two studies are part of the NIMH-funded Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD).
- Bipolar Youth Show Distinct Pattern of Brain Development
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August 28, 2007
Science Update
The first picturess of the brain changing before-and-after the onset of pediatric bipolar disorder reveal a distinct pattern of development, when compared to that seen in healthy youth or in childhood onset schizophrenia.
- Parents' Diagnoses Help to Distinguish Childhood Bipolar Disorder from Severe Mood Dysregulation
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August 6, 2007
Science Update
The parents of children who have bipolar disorder are more likely to have bipolar disorder themselves than the parents of children who have severe mood dysregulation (SMD). This finding challenges the notion of some research that suggests SMD is a type of more broadly defined childhood bipolar disorder.
- NIMH Funds Research for Early Intervention in Childhood Bipolar Disorder
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June 4, 2007
Science Update
NIMH recently approved funding to test the effectiveness of an early intervention in children at high risk for developing bipolar disorder.
- Genetic Roots of Bipolar Disorder Revealed by First Genome-Wide Study of Illness
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May 8, 2007
Press Release
The likelihood of developing bipolar disorder depends in part on the combined, small effects of variations in many different genes in the brain, none of which is powerful enough to cause the disease by itself, a new study shows.
- Bipolar Spectrum Disorder May Be Underrecognized and Improperly Treated
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May 7, 2007
Press Release
A new study supports earlier estimates of the prevalence of bipolar disorder in the U.S. population, and suggests the illness may be more accurately characterized as a spectrum disorder.
- Gene Knockout Unleashes Manic Mouse
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April 5, 2007
Science Update
Mice engineered to lack a specific gene showed behaviors similar to human mania in a study funded in part by NIMH; they were hyperactive, slept less, appeared less depressed and anxious, and craved sugar, cocaine and pleasure stimulation.