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Photograph of a male doctor and a female technician performing an angiography

Also called: PAD

Peripheral arterial disease (PAD) happens when there is a narrowing of the blood vessels outside of your heart. A substance made up of fat and cholesterol, called plaque, builds up on the walls of the arteries that supply blood to the arms and legs. The plaque causes the arteries to narrow or become blocked. This can reduce or stop blood flow, usually to the legs, causing them to hurt or feel numb. If severe enough, blocked blood flow can cause tissue death. If this condition is left untreated, the foot or leg may need to be amputated.

A person with PAD also has an increased risk of heart attack, stroke and transient ischemic attack. You can often stop or reverse the buildup of plaque in the arteries with dietary changes, exercise, and efforts to lower high cholesterol levels and high blood pressure.

National Heart, Lung, and Blood Institute

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