Science News
about Bipolar Disorder
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- Family-Focused Therapy Effective in Treating Depressive Episodes of Bipolar Youth
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September 1, 2008
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Science Update
Adolescents with bipolar disorder who received a nine-month course of family-focused therapy (FFT) recovered more quickly from depressive episodes and stayed free of depression for longer periods than a control group.
- Largest Study of Its Kind Implicates Gene Abnormalities in Bipolar Disorder
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August 18, 2008
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Press Release
The largest genetic analysis of its kind to date for bipolar disorder has implicated machinery involved in the balance of sodium and calcium in brain cells. Researchers supported in part by the National Institute of Mental Health, part of the National Institutes of Health, found an association between the disorder and variation in two genes that make components of channels that manage the flow of the elements into and out of cells, including neurons.
- Mice Expressing Human Genes Bred to Help Unravel Mental Disorders
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June 26, 2008
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Science Update
New mouse strains engineered to express human genes related to mental disorders are being developed under a recently-launched grant program from NIMH's Division of Neuroscience and Basic Behavioral Science.
- Potential New Target Found for Developing Medications to Treat Bipolar Disorder
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June 20, 2008
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Science Update
Medications that target the protein BAG1, which regulates a process that can trigger symptoms in people who have bipolar disorder, may offer a new way of treating the disease, according to NIMH scientists.
- New NIMH Research to Test Innovative Treatments for Children with ADHD
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June 5, 2008
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Science Update
Two new grants funded by NIMH will focus on novel and innovative approaches to treating children who have attention deficit hyperactivity disorder (ADHD).
- Imaging Identifies Brain Regions and Chemicals Underlying Mood Disorders; May Lead to Better Treatments
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May 6, 2008
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Science Update
Recently developed imaging techniques allow the mapping of the brain circuits and chemical systems believed responsible for a range of mood abnormalities including depression and bipolar disorder, and hold promise for improved treatments, scientists say.
- Bipolar Youths’ Misreading of Faces May be Risk Marker for Illness
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March 4, 2008
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Science Update
Youngsters with pediatric bipolar disorder and healthy peers who have first-degree relatives with bipolar disorder share the same difficulty labeling facial emotions, NIMH researchers have discovered.
- Tomorrow’s Antidepressants: Skip the Serotonin Boost?
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February 14, 2008
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Science Update
Even when serotonin levels stayed low, scientists were able to correct abnormal, mental-illness-like behaviors in mice by blocking an enzyme called GSK3ß. The finding adds evidence that molecular targets other than serotonin may lead to better and faster medications for some mental illnesses.
- Faster-Acting Medications for Bipolar Disorder’s Manic Phase May Be Feasible
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January 23, 2008
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Science Update
Scientists may be able to develop faster-acting medications for the manic phase of bipolar disorder, new research shows.
- Mood Disorders Predict Later Substance Abuse Problems
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January 9, 2008
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Science Update
People with manic symptoms and bipolar disorder type II are at significant risk of later developing an alcohol abuse or dependence problem, a long-term study conducted in Switzerland confirms.
