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Science News about Depression

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Obesity Linked with Mood and Anxiety Disorders
July 3, 2006 • Science Update
Results of an NIMH-funded study show that nearly one out of four cases of obesity is associated with a mood or anxiety disorder, but the causal relationship and complex interplay between the two is still unclear.
Switching to a Third Antidepressant Medication May Prove Helpful to Some with Treatment-Resistant Depression
July 1, 2006 • Science Update
The next wave of results from the nation's largest real-world study of treatment-resistant depressionshows that patients had a moderate chance of becoming symptom-free when they switched to a third antidepressant medication, following two previously unsuccessful medication attempts.
Adult Children of Depressed Parents Have Higher Risk of Mental and Physical Illness
June 21, 2006 • Science Update
As children of depressed parents enter adulthood, they continue to suffer greater risk of mental disorders and begin to report more physical illnesses than grown-up children of non-depressed parents.
Intermittent Explosive Disorder Affects up to 16 Million Americans
June 5, 2006 • Press Release
A little-known mental disorder marked by episodes of unwarranted anger is more common than previously thought, a study funded by NIMH has found.
Depression Rates Are Lower in Children Whose Mothers Are Successfully Treated
May 9, 2006 • Science Update
When women treated for depression become symptom-free, their children are less likely to be diagnosed with depression, according to a study published in the March 22/29 issue of the Journal of the American Medical Association.
Properly Timed Light, Melatonin Lift Winter Depression by Syncing Rhythms
May 1, 2006 • Science Update
Most Seasonal Affective Disorder (SAD) symptoms stem from daily body rhythms that have gone out-of-sync with the sun, a NIMH-funded study has found.
New Strategies Help Depressed Patients Become Symptom-Free
March 23, 2006 • Press Release
Results of the nation’s largest depression study show that one in three depressed patients who previously did not achieve remission using an antidepressant became symptom-free with the help of an additional medication and one in four achieved remission after switching to a different antidepressant.
Maintenance Treatment Prevents Recurrence in Older Adults with Single-Episode Depression
March 16, 2006 • Press Release
People age 70 and older who continued taking the antidepressant that helped them to initially recover from their first episode of depression were 60 percent less likely to experience a new episode of depression over a two-year study period than those who stopped taking the medication, according to a study funded by the National Institute of Mental Health (NIMH), part of the National Institutes of Health.
Gene Influences Antidepressant Response
March 15, 2006 • Press Release
Whether depressed patients will respond to an antidepressant depends, in part, on which version of a gene they inherit, a study led by scientists at NIH has discovered. Having two copies of one version of a gene that codes for a component of the brain’s mood―regulating system increased the odds of a favorable response to an antidepressant by up to 18 percent, compared to having two copies of the other, more common version.
Depression Model Leaves Mice with Molecular Scar
February 27, 2006 • Press Release
In addition to triggering a depression-like social withdrawal syndrome, repeated defeat by dominant animals leaves a mouse with an enduring “molecular scar” in its brain that could help to explain why depression is so difficult to cure, suggest researchers funded by NIMH.
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