Purpose: SNAP calculates synonymous and non-synonymous substitution rates based on a set of codon-aligned nucleotide sequences.
Details: Please read the Readme file before using this program! For large alignments (more than 40 sequences) please download the Perl version of SNAP, as these calculations are computationally intensive and slow down our system. Input sequences must be codon-aligned nucleotides. The tool automatically recognizes several common sequence formats. If your input format is not accepted, web-based format conversion sites are available.
WARNING: Unaligned sequences may cause the program to crash or give meaningless ouput.
References: If you use SNAP in a paper, please reference both the HIV database website (www.hiv.lanl.gov) and the following paper. You may also need to reference other papers cited in the Readme file.
