Beta Cell Biology Consortium (BCBC) http://www.betacell.org/ The mission of the BCBC is to facilitate interdisciplinary approaches that will advance our understanding of pancreatic islet cell development, regenerative capacity and function. The long-term goal is to develop a cell-based therapy, or treatments leading to controlled beta-cell renewal, in order to restore normal insulin production to diabetic patients. |
Center for Inherited Disease Research (CIDR) http://www.cidr.jhmi.edu A centralized facility established to provide genotyping and statistical genetics services for investigators seeking to identify genes that contribute to human disease. CIDR concentrates primarily on multifactorial hereditary disease although linage analysis of single gene disorders can also be accommodated. |
Central NIDDK Repository for Biosamples and Data http://www.niddkrepository.org On July 1, 2003, The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH) established Central NIDDK Repositories for biosamples and data collected in clinical studies. The purpose of the Central Repositories is to expand the usefulness of these studies by providing access to the biosamples and data to a wider research community beyond the end of the study. |
Clinical Outcomes Research Inititative (CORI) http://www.cori.org/ The Clinical Outcomes Research Initiative, CORI, provides gastrointestinal physicians, nurses and researchers with software, research data and tailor-made services aimed to advance the overall practice of endoscopy. |
Islet Cell Resource Centers (ICR) http://icr.coh.org/ The three major goals of the ICRs are: 1) to provide pancreatic islets of cGMP-quality to eligible investigators for use in FDA approved, IRB-approved transplantation protocols; 2) to optimize the harvest, purification, function, storage, and shipment of islets while developing tests that characterize the quality and predict the effectiveness of islets transplanted into patients with diabetes mellitus; and 3) to provide pancreatic islets for basic science studies. |
Mouse Metabolic Phenotyping Centers (MMPC) http://www.mmpc.org The Centers are housed at outstanding academic institutions, staffed by experts in state-of-the-art technology. Researchers can ship mice to one of the four Centers and obtain on a fee-for-service basis a range of complex exams used to characterize mouse metabolism, blood composition including hormones, energy balance, eating and exercise, organ function and morphology, physiology and histology. Many tests are done in living animals and are designed to elucidate subtle to complex traits that would define models of metabolic disease. |
Rapid Access to Intervention Development (NIH RAID) http://nihroadmap.nih.gov/raid/ NIH RAID provides a variety of contract services researchers need to bring promising potential therapeutics to trial. |
Sequencing the NOD Mouse http://www.niddk.nih.gov/fund/diabetesspecialfunds/consortia-networks/nod.htm This project is a collaboration of four centers, working on a genome-wide basis, to generate a finished sequence of the non-obese diabetic (NOD) mouse genome, dovetailing with a number of targeted sequencing programs. |
Type 1 Diabetes Preclinical Testing Program (T1D-PtP) http://www.t1diabetes.nih.gov/T1D-PTP The Type 1 Diabetes Rapid Access to Intervention Development (T1D-RAID) program provides resources for pre-clinical development of drugs, natural products, and biologics that will be tested as new therapeutics in type 1 diabetes clinical trials. In some cases, additional preclinical testing is needed to validate potential therapies under disease-specific conditions and in multiple animal models before therapeutics can enter the T1D-RAID development pipeline. In recognition of this need, NIDDK recently established the Type 1 Diabetes Preclinical Testing Program (T1D-PTP) to provide investigators with access to the established facilities and expertise needed to extend, enhance and validate preclinical studies of promising new therapeutics. |
Type 1 Diabetes-Rapid Access to Intervention Development (T1D-RAID) http://www.niddk.nih.gov/fund/diabetesspecialfunds/T1D-RAID/ The T1D-RAID program provides resources for pre-clinical development of drugs, natural products, and biologics that will be tested as new therapeutics in type 1 diabetes clinical trials. |