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EPA Harvard Center for Ambient Particle Health Effects

Harvard University

The EPA Harvard Center for Ambient Particle Health Effects was established to address key scientific issues regarding the health effects of ambient particles. The specific aims of the Center reflected eight of the National Research Council's ten highest research priorities for ambient particle research. To meet these objectives, the Center has focused on three research themes: exposure, susceptibility, and biological mechanisms/dosimetry.

By building the Center around these three defined research themes, the Center has remain focused while maintaining an integrated and inter-disciplinary research approach, both of which was critical to our ability to address key particulate health effect issues in a timely manner. Each of our three research themes included projects that spanned several disciplines and that drew from the expertise and experience of our Center investigators.

Center Publications:

Views: All publications Selected publication types Journal articles Publications submitted after final report

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Main Center Abstract and Reports:

Ambient Particle Health Effects: Exposure, Susceptibility, and Mechanisms

Center Research Projects:

R827353C001 - Assessing Human Exposures to Particulate and Gaseous Air Pollutants

R827353C002 - Quantifying Exposure Error and its Effect on Epidemiological Studies

R827353C003 - St. Louis Bus, Steubenville and Atlanta Studies

R827353C004 - Examining Conditions That Predispose Towards Acute Adverse Effects of Particulate Exposures

R827353C005 - Assessing Life-Shortening Associated with Exposure to Particulate Matter

R827353C006 - Investigating Chronic Effects of Exposure to Particulate Matter

R827353C007 - Determining the Effects of Particle Characteristics on Respiratory Health of Children

R827353C008 - Differentiating the Roles of Particle Size, Particle Composition, and Gaseous Co-Pollutants on Cardiac Ischemia

R827353C009 - Assessing Deposition of Ambient Particles in the Lung

R827353C010 - Relating Changes in Blood Viscosity, Other Clotting Parameters, Heart Rate, and Heart Rate Variability to Particulate and Criteria Gas Exposures

R827353C011 - Studies of Oxidant Mechanisms

R827353C012 - Modeling Relationships Between Mobile Source Particle Emissions and Population Exposures

R827353C013 - Toxicological Evaluation of Realistic Emissions of Source Aerosols (TERESA) Study

R827353C014 - Identifying the Physical and Chemical Properties of Particulate Matter Responsible for the Observed Adverse Health Effects

R827353C015 - Research Coordination Core

R827353C016 - Analytical and Facilities Core

R827353C017 - Technology Development and Transfer Core

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The perspectives, information and conclusions conveyed in research project abstracts, progress reports, final reports, journal abstracts and journal publications convey the viewpoints of the principal investigator and may not represent the views and policies of ORD and EPA. Conclusions drawn by the principal investigators have not been reviewed by the Agency.

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