The Laboratory of Molecular Genetics (LMG), led by Laboratory Chief John W. Drake, Ph.D. (http://www.niehs.nih.gov/research/atniehs/labs/lmg/smdnar/index.cfm), comprises nine research teams investigating fundamental mechanisms of genetic stability and instability. A major NIEHS focus is on long-delayed, environmentally-determined diseases initiated or enhanced by mutations. These include both heritable birth defects and cancer, which together afflict over a million people each year in this country alone. The decades that may elapse between exposure and disease render such genetically initiated conditions difficult to study. Thus, one of the best points of attack is the mutation process itself, including gene mutations, larger chromosomal mutations and genome mutations (losses or gains of entire chromosomes).
The LMG investigates the following topics:
Scientific Support Staff