NOTICE: Experimental software
This software is still under development and has not been fully
tested. Please let us know what you think at
immuno@lanl.gov.
This tool takes two series of tab-delimited HLA types and
compares the HLA frequencies in the two sets. For more
information, see details below, and try Sample Input.
Input
Details
HLA frequency
HLA frequences can be counted two different ways, which differ in
how homozygous alleles are counted.
- Population
- Frequencies of HLA type per
person. Homozygous HLAs are counted once.
- Allele
- Frequencies of HLA type per
allele. Homozygous HLAs are counted twice.
HLA 2/4 digit conversion
HLA type are reported with various resolutions (2, 4 or more
digits). This tools provied three options for handling this.
- Leave HLAs as presented
- The HLA type
are left unchanged and each distinct type is counted
seperately.
- 4-digit HLA comparison
- Silent
mutations are ignored; HLA types with more than 4 digits precision
are truncated. HLA type with 2 digits are left unchanged.
- 2-digit HLA comparison
- All HLA type
are converted to 2 digits. The conversion serotype information if
available or else the 2-digit HLA family.