The Norway Facial Clefts Study generated data that the Epidemiology Branch and its collaborators published in peer-reviewed journal articles. To find out more about the study, please click the following links to journal articles and abstracts.
Jugessur A, Lie RT, Wilcox AJ, Murray JC, Taylor JA, Saugstad OD, Vindenes H, Åbyholm F. Variants of developmental genes (TGFA, TGFB3, and MSX1) and their associations with facial clefts: A case-parent triad analysis. Genet Epidemiol 24:230-9; 2003.
[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12652527)[download the PDF](http://www3.interscience.wiley.com/cgi-bin/fulltext/104083938/PDFSTART)
Jugessur A, Wilcox AJ, Lie RT, Murray JC, Taylor J, Ulvik A, Drevon CA, Vindenes HA, Åbyholm F. Exploring the effects of methylenetetrahydrofolate reductase gene variants C677T and A1298C on the risk of orofacial clefts in 261 Norwegian case-parent triads. Am J Epidemiol 157:1083-91; 2003.
[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12796044)[Full Text](http://aje.oupjournals.org/cgi/content/full/157/12/1083)[download the PDF](http://aje.oupjournals.org/cgi/reprint/157/12/1083)
Jugessur A, Lie RT, Wilcox AJ, Murray JC, Taylor JA, Saugstad OD, Vindenes HA, Åbyholm FE. Cleft palate, transforming growth factor alpha gene variants, and maternal exposures: assessing gene-environment interactions in case-parent triads. Genetic Epidemiol 25:367-74; 2003.
[Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14639706)[download the PDF](http://www3.interscience.wiley.com/cgi-bin/fulltext/106566189/PDFSTART)
Boyles AL, Wilcox AJ, Taylor JA, Meyer K, Fredriksen A, Ueland PM, Drevon CA, Vollset SE, Lie RT. Folate and one-carbon metabolism gene polymorphisms and their associations with oral facial clefts. Am J Med Genet A 146A:440-9; 2008.
Lie RT, Wilcox AJ, Taylor J, Gjessing HK, Saugstad OD, Aabyholm F, Vindenes H. Maternal smoking and oral clefts: the role of detoxification pathway genes. Epidemiology 19:606-15; 2008.
Johansen AM, Lie RT, Wilcox AJ, Andersen LF, Drevon CA. Maternal dietary intake of vitamin A and risk of orofacial clefts: a population-based case-control study in Norway. Am J Epidemiol 167:1164-70; 2008. Epub 2008 Mar 14.
Jugessur A, Rahimov F, Lie RT, Wilcox AJ, Gjessing HK, Nilsen RM, Nguyen TT, Murray JC. Genetic variants in IRF6 and the risk of facial clefts: single-marker and haplotype-based analyses in a population-based case-control study of facial clefts in Norway. Genet Epidemiol 32:413-24; 2008.
Sivertsen A, Wilcox AJ, Skjaerven R, Vindenes HA, Abyholm F, Harville E, Lie RT. Familial risk of oral clefts by morphological type and severity: population based cohort study of first degree relatives. BMJ 336:432-4; 2008. Epub 2008 Feb 4.
DeRoo LA, Wilcox AJ, Drevon CA, Lie RT. First-Trimester Maternal Alcohol Consumption and the Risk of Infant Oral Clefts in Norway: A Population-based Case-Control Study. Am J Epidemiol 2008 Jul 30. [Epub ahead of print]
Nguyen RH, Wilcox AJ, Moen BE, McConnaughey DR, Lie RT. Parent's occupation and isolated orofacial clefts in Norway: a population-based case-control study. Ann Epidemiol 17:763-71; 2007. Epub 2007 Jul 30.
Harville EW, Wilcox AJ, Lie RT, Abyholm F, Vindenes H. Epidemiology of cleft palate alone and cleft palate with accompanying defects. Eur J Epidemiol 22:389-95; 2007. Epub 2007 May 5.
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