Tissue-Culture Facility
At EMSL, researchers use the single-molecule fluorescence/patch clamp microscope to combine high-sensitivity fluorescence imaging simultaneously with physiological measurements to identify real-time molecular interactions and conformational changes of cell-membrane receptors and their functional consequences.
The study of individual proteins in the membrane of living cells is enabled by the presence of a tissue culture facility adjacent to the microscopes. The facility supports the growth of eukaryotic primary cells or cell-lines, including human cell lines. In addition to a bio-hood, the facility includes CO2 incubators, a centrifuge, 37°C water bath and a shaker.
