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Lithium Blocks Enzyme To Help Cells’ Clocks Keep On Tickin’
February 17, 2006 • Science Update
NIMH-funded researchers have discovered how lithium likely fixes body clocks gone awry, stabilizing sleep-wake cycles and other daily rhythms disturbed along with mood in bipolar disorder.
Mice Lacking Social Memory Molecule Take Bullying in Stride
February 9, 2006 • Press Release
The social avoidance that normally develops when a mouse repeatedly experiences defeat by a dominant animal disappears when it lacks a gene for a memory molecule in a brain circuit for social learning, scientists funded by NIMH have discovered.
Stopping Antidepressant Use While Pregnant May Pose Risks
February 1, 2006 • Science Update
Pregnant women who discontinue antidepressant medications may significantly increase their risk of relapse during pregnancy, a new NIMH-funded study has found.
Nobelist Discovers Antidepressant Protein in Mouse Brain
January 6, 2006 • Press Release
A protein that seems to be pivotal in lifting depression has been discovered by a Nobel Laureate researcher funded by NIMH.
Initial Results Help Clinicians Identify Patients with Treatment-Resistant Depression
January 1, 2006 • Press Release
Initial results of the nation’s largest clinical trial for depression have helped clinicians to track “real world” patients who became symptom-free and to identify those who were resistant to the initial treatment.
NIMH Study To Guide Treatment Choices for Schizophrenia (Phase 1 Results)
September 19, 2005 • Press Release
A large study funded by NIH's National Institute of Mental Health (NIMH) provides, for the first time, detailed information comparing the effectiveness and side effects of five medications
Actor-Patients´ Requests for Medications Boost Prescribing for Depression
April 27, 2005 • Press Release
Critics of direct-to-consumer marketing fear the advertisements lead to over-prescribing. Proponents believe they can serve a useful educational function.
New Neurons Born in Adult Rat Cortex
February 2, 2005 • Press Release
Recent evidence suggesting that antidepressants may act by triggering the birth of new neurons in the adult hippocampus the brain’s memory hub, has heightened interest in such adult neurogenesis and raised the question: Could new neurons also be sprouting up in the parts of the adult brain involved in the thinking and mood disturbances of depression and anxiety?
Mutant Gene Linked to Treatment-Resistant Depression
December 13, 2004 • Science Update
A mutant gene that starves the brain of serotonin, a mood-regulating chemical messenger, has been discovered and found to be 10 times more prevalent in depressed patients than in control subjects, report researchers funded by the National Institutes of Health’s National Institute of Mental Health (NIMH) and National Heart Lung and Blood Institute (NHLBI).
Psychotherapy, Medications Best for Youth With Obsessive Compulsive Disorder
October 28, 2004 • Press Release
Children and adolescents with Obsessive Compulsive Disorder (OCD) respond best to a combination of both psychotherapy and an antidepressant, a major clinical trial has found.
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