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- Targeted Therapy Halves Suicide Attempts in Borderline Personality Disorder
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July 3, 2006
Science Update
Dialectical Behavior Therapy (DBT) reduced suicide attempts by half compared with other types of psychotherapy available in the community in patients with borderline personality disorder, an NIMH-funded study has found.
- Switching to a Third Antidepressant Medication May Prove Helpful to Some with Treatment-Resistant Depression
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July 1, 2006
Science Update
The next wave of results from the nation's largest real-world study of treatment-resistant depressionshows that patients had a moderate chance of becoming symptom-free when they switched
to a third antidepressant medication, following two previously unsuccessful medication attempts.
- Antidepressant Does Not Reduce Risk Of Relapse Among Patients With Anorexia Nervosa
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June 14, 2006
Science Update
An NIMH-funded study has concluded that the antidepressant medication fluoxetine (Prozac) is no more effective than placebo in preventing relapse among patients with anorexia nervosa who had achieved a healthy weight during inpatient or day-program treatment.
- Intermittent Explosive Disorder Affects up to 16 Million Americans
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June 5, 2006
Press Release
A little-known mental disorder marked by episodes of unwarranted anger is more common than previously thought, a study funded by NIMH has found.
- Depression Rates Are Lower in Children Whose Mothers Are Successfully Treated
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May 9, 2006
Science Update
When women treated for depression become symptom-free, their children are less likely to be diagnosed with depression, according to a study published in the March 22/29 issue of the Journal of the American Medical Association.
- Studies Offer New Information About Treatment Choices for Schizophrenia — Phase 2 Results
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April 1, 2006
Science Update
A national clinical trial comparing clozapine with other new-generation antipsychotic medications for the treatment of chronic schizophrenia has shown that people who switched to clozapine from their first medication because it failed to manage symptoms adequately were twice as likely to continue treatment as patients who switched to other antipsychotic medications.
- New Strategies Help Depressed Patients Become Symptom-Free
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March 23, 2006
Press Release
Results of the nation’s largest depression study show that one in three depressed patients who previously did not achieve remission using an antidepressant became symptom-free with the help of an additional medication and one in four achieved remission after switching to a different antidepressant.
- Gene Influences Antidepressant Response
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March 15, 2006
Press Release
Whether depressed patients will respond to an antidepressant depends, in part, on which version of a gene they inherit, a study led by scientists at NIH has discovered. Having two copies of one version of a gene that codes for a component of the brain’s mood―regulating system increased the odds of a favorable response to an antidepressant by up to 18 percent, compared to having two copies of the other, more common version.
- Early Findings from Largest NIMH-Funded Research Program on Bipolar Disorder Begin to Build Evidence-Base on Best Treatment Options
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February 1, 2006
Science Update
Findings from an NIMH research program on bipolar disorder provide much needed long-term data on the chronic, recurrent course of the disorder, and begin the work of building an evidence-base on the best treatments for those with the disorder.
- Initial Results Help Clinicians Identify Patients with Treatment-Resistant Depression
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January 1, 2006
Press Release
Initial results of the nation’s largest clinical trial for depression have helped clinicians to track “real world” patients who became symptom-free and to identify those who were resistant to the initial treatment.