Grant Types

This is an NIAID-specific mechanism-based list from NIH's Types of Grant Programs. Read more at Selection of Appropriate Funding Mechanisms SOP.

Activity Codes Used by NIAID

F K P R S T U Y

Fellowship Programs -- National Research Service Awards

• F31, Individual Diversity Predoctoral Fellow
• F32, Individual Postdoctoral Fellow
• F33, Individual Senior Fellow
• F35, Intramural Individual Postdoctoral Fellow

Research Career Development Awards

• K01, Mentored Research Scientist Award
• K02, Independent Scientist Award
• K08, Mentored Clinical Scientist Award
• K22, NIAID Research Scholar Award
• K23, Mentored Patient-Oriented Research Award
• K24, Midcareer Investigator Award in Patient-Oriented Research
• K25, Mentored Quantitative Research Award
• K30, Clinical Research Curriculum Award
• K99/R00, NIH Pathway to Independence Award

Research Program Project and Center Grants

• P01, Program Project
• P30, Center Core Grant
• P50, Specialized Center

Research Project Grants

• R00, see K99/R00, NIH Pathway to Independence Award
• R01, Research Project Grant
• R03, Small Research Grant
• R09, Scientific Review Evaluation Award
• R13, Conference Grant
• R15, Academic Research Enhancement Award (AREA)
• R18, Research Demonstration and Dissemination Project
• R21, Exploratory/Developmental Research Grant, Phase I
• R21/R33, Phased Innovation Award
• R24, Resource-Related Research Project
• R25, NIAID Science Education Award
• R33, Exploratory/Developmental Research Grant, Phase II
• R34, NIAID Clinical Trial Planning Grant
• R37, Method to Extend Research in Time (MERIT) Award
• R41 and R42, Small Business Technology Transfer (STTR) Grant
• R43 and R44, Small Business Innovation Research (SBIR) Grant
• R56, High-Priority, Short-Term Project Award (Bridge Award)
• RC1, Challenge Grant for High-Priority Product Development

Research-Related Programs

• SC1, Support of Competitive Research (SCORE) Research Advancement Award
• SC2, Support of Competitive Research (SCORE) Pilot Project Award

Training Programs - -- National Research Service Awards

• TU2, Institutional Training Programs Involving NIH Intramural Faculty
• T15, Continuing Education Training Grant
• T32, Institutional Research Training Grant
• T35, Short-Term Institutional Research Training Grant

Cooperative Agreements

• U01, Research Project
• U13, Conferences and Scientific Meetings
• U19, Research Program
• U24, Resource-Related Research Project
• U42, Animal Model, Animal, and Biomedical Materials Resources (NCRR)
• U43, Small Business Innovation Research (SBIR), Phase I
• U44, Small Business Innovation Research (SBIR), Phase II
• U54, Specialized Center
• U56, Exploratory Grant
• UC1, NIH Challenge Grant and Partnerships Program, Phase II
• UC6, Construction Grant
• UC7, National Biocontainment Laboratory Operation

Interagency or Intra-agency Agreements

• Y01, NIH Interagency Agreement
• Y02, NIH Intra-agency Agreement

Activity Code Descriptions

Fellowship Programs -- National Research Service Awards

F31
Individual Diversity Predoctoral Fellow -- provides individual fellowships to predoctoral trainees from underrepresented groups. For more information, see the F31 Guide notice (December 12, 2006) and the Fellowship Grants SOP.

F32
Individual Postdoctoral Fellow -- provides individual fellowships to postdoctoral trainees. For more information, see the F32 Guide notice (December 12, 2006) and the Fellowship Grants SOP.

F33
Individual Senior Fellow -- provides opportunities for experienced scientists to make major changes in the direction of their research careers, broaden their scientific background, or acquire new research capabilities. For more information, see the F33 Guide notice (December 15, 2006) and the Fellowship Grants SOP.

F35
Intramural Individual Postdoctoral Fellow -- supports a postdoctoral trainee in the NIH intramural program.

Research Career Development Awards

K01
Mentored Research Scientist Award -- supports clinicians and Ph.D.s exclusively in epidemiology and outcomes research. For more information, see the K01 Guide notice (October 4, 2005) and the Career Development Grants SOP.

K02
Independent Scientist Award -- supports more established investigators who are newly independent and demonstrate a need for intensive research focus, in all fields of NIAID's mission. It replaces the old K02 and K04 (research career development award). Also supports established clinical scientists and Ph.D.s in the fields of epidemiology and outcomes research as announced in the K02 Guide notice (August 15, 2006). Candidates must have independent, peer-reviewed research support. For more information, see the Career Development Grants SOP.

K08
Mentored Clinical Scientist Award -- supports comprehensive research experience leading to independence, replacing the old K08, K11, and K15. Awards are from three to five years and may include didactic studies. For more information, see the K08 Guide notice (August 7, 2006) and the Career Development Grants SOP.

K22
NIAID Research Scholar Award -- provides start-up support for postdocs making the transition to assistant professors at an academic institution. For more information, see the K22 Guide notice (April 2, 2007) and the Career Development Grants SOP.

K23
Mentored Patient-Oriented Research Award -- supports young scientists who want to conduct patient-oriented research. For more information, see the K23 Guide notice (July 22, 2005) and the Career Development Grants SOP.

K24
Midcareer Investigator Award in Patient-Oriented Research -- supports mid-career scientists who are already conducting patient-oriented research and would like to spend more time mentoring young clinicians interested in the same kind of research. For more information, see the K24 Guide notice (April 18, 2008) and the Career Development Grants SOP.

K25
Mentored Quantitative Research Award -- supports junior faculty-level investigators with quantitative scientific and engineering backgrounds outside of biology or medicine who have the potential to integrate their expertise with biomedicine and develop into productive investigators with a period of mentored study and research. For more information, see the K25 Guide notice (December 2, 2005) and the Career Development Grants SOP.

K30
Clinical Research Curriculum Award -- supports the development of new didactic programs in clinical research at institutions that do not currently offer such programs or the expansion of existing programs.

K99/R00
NIH Pathway to Independence Award -- supports salary and research expenses for up to two years in the mentored K99 phase for new investigators. The R00 phase provides salary and fringe benefits to continue the research project independently. In the second phase the investigator must have a tenure-track, full-time assistant professor position or equivalent. The transition from a K99 to an R00 is not automatic. NIAID makes very few awards. For more information, see the K99/R00 Guide notice (January 12, 2007) and our Pathway to Independence (K99/R00) SOP.

Research Program Project and Center Grants

P01
Program Project -- provides an institution with support of a multidisciplinary, often long-term research program with an objective or theme involving the organized efforts of groups of investigators. Awarded on behalf of a principal investigator, the grant can support projects and shared resources. See Instructions for Preparing a Multiproject Grant Application.

P30
Center Core Grant -- supports shared resources and facilities for a multidisciplinary research team or a group of investigators focusing on a common research topic. Funded independently of a center's component or program projects, the core grant provides accessible resources. See Instructions for Preparing a Multiproject Grant Application.

P50
Specialized Center -- supports all aspects of R&D from basic to clinical and may involve ancillary support activities such as patient care. They differ from program project grants in that they are usually developed in response to an institute initiative and subsequently receive continuous attention from its staff. Centers also may serve as regional or national resources for special research. See Instructions for Preparing a Multiproject Grant Application.

Research Project Grants

R00
See K99/R00, NIH Pathway to Independence Award.

R01
Research Project Grant -- provides support to an institution (domestic or foreign) on behalf of a principal investigator for a project proposed by the investigator. Most NIH research is through the R01. Rarely, such a grant may be awarded directly to an individual. For more information, see the parent R01 announcement (November 20, 2006).

R03
Small Research Grant -- provides limited research support usually for preliminary, short-term projects. They are nonrenewable. NIAID accepts investigator-initiated applications in response to the parent R03 announcement (March 2, 2006) as well as its own R03 RFAs and PAs. For more information, see the Small and Exploratory/Developmental Research Grants SOP.

R09
Scientific Review Evaluation Award -- provides the chairman of a review group with funds for operation.

R13
Conference Grant -- provides funding for conferences to exchange and disseminate information related to program interests. Generally, such awards are modest and limited to participation with other organizations. Among the costs eligible for support are salaries, equipment rental, travel, consultant services, and supplies. Prospective applicants should inquire in advance about an institute's interest. For more information, see the parent R13 announcement (April 16, 2008) and the Conference Awards SOP.

R15
Academic Research Enhancement Award (AREA) -- supports scientists at eligible institutions for small-scale, new, or expanded, health-related research projects such as pilot projects and feasibility studies; development, testing, and refinement of research techniques; secondary analysis of available data sets; and similar work showing research capability. The award is for small four-year colleges and universities that train a significant number of research undergraduates but have a limited share of NIH funds. For more information, see the parent R15 announcement (October 26, 2005) and the Academic Research Enhancement Awards SOP.

R18
Research Demonstration and Dissemination Project -- provides support to develop, test, and evaluate health services and foster the application of knowledge to control disease.

R21
Exploratory/Developmental Research Grant, Phase I -- encourages new research in a given program area. Support generally is restricted for level and time. NIAID accepts investigator-initiated applications in response to the parent R21 announcement (March 2, 2006) as well as its own R21 RFAs and PAs. For more information, see the Small and Exploratory/Developmental Research Grants SOP.

R21/R33
Phased Innovation Award -- provides a milestone-driven, two-phased award with little or no gap in funding. Both components are submitted and reviewed simultaneously. NIAID staff assess eligibility for the transition to the R33, which is dependent on the successful completion of negotiated milestones, continued priority of the topic, and availability of funds. NIAID accepts applications only in response to RFAs and PAs that specify the R21/R33 mechanism.

R24
Resource-Related Research Project -- supports research projects to enhance the capacity of resources that serve biomedical research.

R25
NIAID Science Education Award -- provides support to develop or implement a program in education, information, training, technical assistance, coordination, or evaluation. For more information, see the R25 Guide notice (October 2, 2007).

R33
Exploratory/Developmental Research Grant, Phase II -- provides a second phase of support for innovative, exploratory, and developmental research begun as an R21 award. Only R21 awardees are eligible to apply for R33 support. NIAID accepts applications for investigator-initiated projects and in response to RFAs and PAs that specify the R33 mechanism. For more information, see the Small and Exploratory/Developmental Research Grants SOP.

R34
NIAID Clinical Trial Planning Grant -- supports initial development of a clinical trial, e.g., establishing a research team, developing tools for managing data and overseeing the research, and developing a trial design, protocol, recruitment strategies, and procedure manuals. For more information, see the R34 Guide notice (May 3, 2006) and Investigator-Initiated Clinical Trials Resources Web site.

R37
Method to Extend Research in Time (MERIT) Award -- provides long-term support to a limited number of investigators who are likely to continue to perform in an outstanding manner. The initial 5-year award may be followed by a 3- to 5-year extension. Awardees are selected by NIH staff and advisors. For more information, see the MERIT Awards and Extensions SOP.

R41 and R42
Small Business Technology Transfer (STTR) Grant -- supports collaborative research by a small business with a research institution on a project intended for commercialization. A Phase I grant (R41) is used to establish the technical merit and feasibility of the research concept. A Phase II grant (R42) supports further research leading to a product or service. For more information, see the parent R41 and R42 announcement (January 25, 2008) and the SBIR and STTR SOP.

R43 and R44
Small Business Innovation Research (SBIR) Grant -- supports small business research on a project intended for commercialization. A Phase I grant (R43) is used to establish the technical merit and feasibility of the research concept. A Phase II grant (R44) supports further research leading to a product or service. For more information, see the parent R43 and R44 announcement (January 25, 2008) and the SBIR and STTR SOP.

R56
High-Priority, Short-Term Project Award (Bridge Award) -- provides interim, nonrenewable research support for up to one year to highly meritorious R01 applications with percentiles beyond the payline. An R56 enables an applicant to gather additional data to revise a new or renewal application; it ends when the applicant obtains a competing award. Both NIH and NIAID have bridge programs. For more information, see the NIH R56 Guide notice (March 14, 2007) and the NIAID R56-Bridge Award SOP.

RC1
Challenge Grant for High-Priority Product Development -- promotes rapid biomedical or biotechnology R&D to benefit public health.

Research-Related Programs

SC1
Support of Competitive Research (SCORE) Research Advancement Award -- supports investigator-initiated research projects for faculty at minority-serving institutions who are at the most advanced stages of development and are planning to transition to other major external (non-SCORE) sources of support. For more information, see the SC1 Guide notice (November 16, 2007).

SC2
Support of Competitive Research (SCORE) Pilot Project Award -- supports investigator-initiated pilot research projects for faculty at minority-serving institutions who are at the beginning stages of a research career and who are interested in testing a new idea or generating preliminary data. Also supports more experienced investigators interested in switching to a different field of research. PIs who successfully complete a pilot project may apply for an SC1. For more information, see the SC2 Guide notice (November 16, 2007).

Training Programs - -- National Research Service Awards

TU2
Institutional Training Programs Involving NIH Intramural Faculty -- the cooperative agreement counterpart to the T32, enables institutions to provide research training to graduate students and postdocs in shortage areas. Awards involve NIH intramural staff who serve as a part of the training faculty and participate in the operation of the training program.

T15
Continuing Education Training Grant -- assists professional schools and other public and nonprofit institutions in establishing, expanding, or improving programs of continuing professional education, especially for programs involving new developments in the science of technology.

T32
Institutional Research Training Grant -- funds academic institutions for training predoctoral and postdoctoral candidates. For more information, see the T32 Guide notice (August 1, 2008) and the Research Training Grants SOP.

T35
Short-Term Institutional Research Training Grant -- provides research training during off-quarters or summer periods. For more information, see the T35 Guide notice (August 1, 2008) and the Research Training Grants SOP.

Cooperative Agreements

U01
Research Project -- sets up an assistance relationship between NIH and the award recipient for projects similar to grants in which NIH acts as a partner in the research effort. For more information, see the Cooperative Agreements (U) SOP.

U13
Conferences and Scientific Meetings -- supports international, national, or regional meetings, conferences, and workshops involving substantial programmatic involvement by NIAID staff. For more information, see the Cooperative Agreements (U) SOP and the Conference Awards SOP.

U19
Research Program -- supports multiple projects directed toward a theme or program goal requiring a multidisciplinary and often long-term approach. For more information, see the Cooperative Agreements (U) SOP.

U24
Resource-Related Research Project -- supports cofunded research projects to improve the capacity of resources that serve biomedical research. For more information, see the Cooperative Agreements (U) SOP.

U42
Animal Model, Animal, and Biomedical Materials Resources (NCRR) -- develops and supports a mammalian or nonmammalian model, animal, or biological materials resource for investigators without regard to scientific discipline or NIH program. Nonmammalian resources include nonmammalian vertebrates, invertebrates, cell systems, and nonbiological systems. For more information, see the Cooperative Agreements (U) SOP.

U43
Small Business Innovation Research (SBIR), Phase I -- supports cofunded cooperative R&D projects between small businesses and research institutions. Phase I grants support projects to establish the technical merit and feasibility of R&D ideas that may lead to commercial products or services. For more information, see the Cooperative Agreements (U) SOP.

U44
Small Business Innovation Research (SBIR), Phase II -- supports cofunded cooperative R&D projects between small businesses and research institutions. Phase II grants support in-depth development of those ideas. For more information, see the Cooperative Agreements (U) SOP.

U54
Specialized Center -- supports research and development from basic to clinical, including ancillary supportive activities that create a multidisciplinary focus on a disease or a biomedical problem. Centers may also serve as regional or national resources for special research purposes. For more information, see the Cooperative Agreements (U) SOP.

U56
Exploratory Grant -- supports planning for new programs, expansion or modification of existing resources, and feasibility studies for interdisciplinary programs that may lead to specialized or comprehensive centers. For more information, see the Cooperative Agreements (U) SOP.

UC1
NIH Challenge Grant and Partnerships Program, Phase II -- promotes joint ventures between NIH and both domestic and global entities to facilitate rapid biomedical or biotechnology R&D for infectious diseases to benefit public health; projects should have a commercial potential that could not have been attained without matching funds. For more information, see the Cooperative Agreements (U) SOP.

UC6
Construction Grant -- provides financial support, substantial programmatic involvement, and technical assistance for designing, constructing, and commissioning of laboratories to be used as extramural facilities for bio-defense and emerging infectious diseases research. For more information, see the Cooperative Agreements (U) SOP.

UC7
National Biocontainment Laboratory Operation -- supports core and shared resources for national biocontainment laboratories to develop and maintain the resources and facilities needed for national, regional, and local biodefense and emerging infectious diseases research. For more information, see the Cooperative Agreements (U) SOP.

Interagency or Intra-agency Agreements

Y01
NIH Interagency Agreement -- transfers funds from NIH to a federal organization outside the Department of Health and Human Services to acquire specific products, services, or studies. For more information, see the Inter- and Intra-Agency Agreements SOP.

Y02
NIH Intra-agency Agreement -- transfers funds to another NIH component or another organization within the Department of Health and Human Services to acquire products, services, or studies. For more information, see the Inter- and Intra-Agency Agreements SOP.