U.S. NATIONAL INSTITUTES OF HEALTH
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LEADING THE FEDERAL EFFORT ON AGING RESEARCH

2000 News Releases


Scientists Suspect New Genetic Risk Factor for Late Onset Alzheimer's Disease

December 21, 2000 -- Three new, separate research studies suggest that a gene or genes on chromosome 10 may be risk factors for late onset Alzheimer's disease (AD).

  
 
New Study Links Head Injury, Severity of Injury, with Alzheimer's Disease

October 23, 2000 -- A new analysis of head injuries among World War II veterans links serious head injury in early adulthood with Alzheimer's disease (AD) in later life.

  
 
Nasal Alzheimer's Vaccine Successfully Tested in Mice

September 28, 2000 -- Nasal administration of synthetic beta amyloid peptide reduces potentially damaging Alzheimer's disease-like plaques in the brains of test mice and may one day be tested in clinical trials for its ability to vaccinate against plaque formation in people with Alzheimer's disease (AD), according to a new study by researchers at Harvard Medical School.

  
 
Odor Identification Test May Help Predict Alzheimer's Disease

August 28, 2000 -- A simple odor identification test might help doctors more accurately predict which individuals with mild cognitive impairment will go on to develop Alzheimer's disease.

  
 
Study Suggests ERT Stimulates Blood Flow to Key Memory Centers in the Brain

June 27, 2000 -- In the first long-term study of its kind, researchers at the National Institute on Aging recently used neuroimaging technology to find evidence that the brains of post-menopausal women who receive estrogen replacement therapy (ERT) age differently and have significantly greater blood flow to areas involved in memory formation than the brains of women who do not receive hormone replacement.

  
 
Enzyme May Protect Against Brain Disorders

June, 2000 -- Telomerase, an enzyme believed to have a role in determining the life span of cells, also may protect nerve cells against decreased function and premature death caused by Alzheimer's disease and other age-related neurological disorders.

  
 
MRI May Prove Powerful Tool In Predicting Development of Alzheimer's Disease

March 29, 2000 -- Structural Magnetic Resonance Imaging (MRI) could become an important tool for characterizing and diagnosing Alzheimer's disease (AD) in its very early stages, well before clinical signs appear, according to a new study by researchers in Boston.

  
 
Estrogen Replacement Therapy Not Effective For Treatment of Alzheimer's Disease in Some Women

February 23, 2000 -- Estrogen replacement therapy (ERT) does not improve the memory or function of hysterectomized women with mild to moderate Alzheimer's disease, according to a new research report.

  
 
Low-Dose Prednisone Found Ineffective Against Alzheimer's Disease; Researchers Continue to Look at NSAIDs, Other Drugs

February 8, 2000 -- A low-dose regimen of the steroid prednisone, an anti-inflammatory drug, is not effective in the treatment of Alzheimer's disease (AD), according to findings from a new clinical trial.

  
 
NIA To Study COX-2 Inhibitor, Other NSAID as New Treatment for Alzheimer's Disease
February 8, 2000 -- The National Institute on Aging (NIA) is launching a clinical trial to determine whether treatment with certain nonsteroidal anti-inflammatory drugs (NSAIDs) will slow cognitive and clinical decline in patients with Alzheimer's disease (AD).  
 
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