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Cartoon scientist reading about IACUC Your IACUC is an oversight body appointed by an official at your institution, such as the chief executive officer. The Office of Laboratory Animal Welfare relies on the IACUC to enforce PHS policy and your institution's animal policies. IACUCs do the following.

  • Review and approve animal use protocols, including significant changes* to previously approved protocols.
  • Monitor your animal care and use program, including a semi-annual inspection of animal facilities.
  • Hold orientation programs on institutional animal policies and procedures, e.g., what is expected, which protocol forms to use, and where to get animals.
  • Evaluate compliance with institutional policies.
  • Report annually and notify OLAW of suspensions and instances of serious noncompliance with policy. See the February 24, 2005, Guide notice for guidance on what an IACUC should report to OLAW.

Find out your institution's policies before you plan your research. In most institutions, policies for research animals are a combination of institutional and USDA and PHS requirements. Some are more stringent than others, so a procedure you performed at another institution may not be acceptable at your current workplace.

* Institutional definitions of a "significant change" vary. Be sure you know your institution's policy. Implementing a significant change without IACUC prior approval is a serious violation of PHS policy. See What is considered a significant change to a project that would require IACUC review? for more information.

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