- Genomics:GTL research - to underpin the development of biotechnology solutions for energy, the environment, and carbon sequestration. This program will develop genome-scale technologies needed to understand the workings of microbial and plant systems from proteomics to metabolomics to regulatory networks to ecogenomics. A central element of Genomics:GTL is the development of the computational capabilities and systems needed to model complex biological systems. Thus, Genomics:GTL is a joint program with the Office of Advanced Scientific Computing Research.
- GTL Biological Research Centers
- Low dose radiation research - to understand and characterize the risks to human health from exposures to low levels of radiation.
- Radiopharmaceutical and Molecular Nuclear Medicine Science
- The Advanced Biomedical Technology (ABT) Research Program - supports multidisciplinary, multi-institutional projects tha address high-risk medical technology problems. The research ultimately will led to the development of medical instruments and techniques that can be transferred to the National Institutes of Health for clinical testing or to industry for further development.
- Advanced Imaging Instrumentation
- ELSI research - to anticipate and address ethical, legal, and social implications arising from BER research.
- DOE Human Subjects Protection Program – to ensure compliance with Federal regulations and DOE Orders to protect human subjects. All research conducted at DOE, supported with DOE funds, or performed by DOE employees must comply.
- Structural Biology - to develop and support DOE national user facilities for use in fundamental structural biology.
- DOE Joint Genome Institute Production Genomics Facility for high throughput DNA sequencing.
- Center for Comparative and Functional Genomics providing expertise in mouse genetics (experimental design, mutagenesis, transgenesis, phenotyping, cryopreservation of embryos and germ cells, and data management) with capabilities for mouse gene discovery and functional characterization.