Also called: Also called: Non-Hodgkin's lymphoma
Lymphoma is a cancer of a part of the immune system called the lymphatic system. There are many types of lymphoma. One type is called Hodgkin's disease. The rest are called non-Hodgkin's lymphoma.
Non-Hodgkin's lymphomas begin when a type of white blood cell, called a T cell or B cell, becomes abnormal. The cell divides again and again, making more and more abnormal cells. These abnormal cells can spread to almost any other part of the body. Most of the time, doctors can't determine why a person gets non-Hodgkin's lymphoma.
Non-Hodgkin's lymphoma can cause many symptoms, such as
- Swollen, painless lymph nodes in the neck, armpits or groin
- Unexplained weight loss
- Fever
- Soaking night sweats
- Coughing, trouble breathing or chest pain
- Weakness and tiredness that don't go away
- Pain, swelling or a feeling of fullness in the abdomen
Your doctor will perform an exam and lab tests to determine if you have lymphoma.
National Cancer Institute
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What Is Non-Hodgkin Lymphoma?(American Cancer Society) - http://www.cancer.org/docroot/cri/content/cri_2_4_1x_what_is_non_hodgkins_lymphoma_32.asp
Also available in Spanish http://www.cancer.org/docroot/esp/content/esp_5_1x_que_es_32.asp?
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What You Need to Know about Non-Hodgkin Lymphoma
(National Cancer Institute) - http://www.cancer.gov/cancertopics/wyntk/non-hodgkins-lymphoma
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Lymphomas: A Guide for Patients and Caregivers(Leukemia & Lymphoma Society) - Large PDF file - http://www.leukemia-lymphoma.org/attachments/National/br_1178218354.pdf
Also available in Spanish http://www.leukemia-lymphoma.org/attachments/National/br_1139861955.pdf
- Survival Rates Improve for Kids with Blood Cancers(09/10/2008, HealthDay) - http://www.nlm.nih.gov/medlineplus/news/fullstory_69135.html
- New Lymphoma Drug Shows Promise(08/14/2008, HealthDay) - http://www.nlm.nih.gov/medlineplus/news/fullstory_68167.html
- Incidence of Mantle Cell Lymphoma on Rise(07/18/2008, HealthDay) - http://www.nlm.nih.gov/medlineplus/news/fullstory_67140.html
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How Is Non-Hodgkin Lymphoma Diagnosed?(American Cancer Society) - http://www.cancer.org/docroot/cri/content/cri_2_4_3x_how_is_non-hodgkins_lymphoma_diagnosed_32.asp
Also available in Spanish http://www.cancer.org/docroot/esp/content/esp_5_1x_deteccion_y_sintomas_32.asp?
- How Is Non-Hodgkin Lymphoma Staged?(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_3X_How_is_non-Hodgkins_lymphoma_staged_32.asp?rnav=cri
- How Is Waldenstrom Macroglobulinemia Diagnosed?(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_3x_How_Is_Waldenstroms_Macroglobulinemia_Diagnosed.asp?rnav=cri
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Understanding Blood Counts(Leukemia & Lymphoma Society) - http://www.leukemia-lymphoma.org/all_mat_toc.adp?item_id=9452
Also available in Spanish http://www.leukemia-lymphoma.org/all_mat_toc.adp?item_id=186980
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Adult Non-Hodgkin's Lymphoma (PDQ): Treatment(National Cancer Institute) - http://www.cancer.gov/cancertopics/pdq/treatment/adult-non-hodgkins/patient/
Also available in Spanish http://www.cancer.gov/espanol/pdq/tratamiento/no-hodgkin-adultos/patient/
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AIDS-Related Lymphoma (PDQ): Treatment(National Cancer Institute) - http://www.cancer.gov/cancertopics/pdq/treatment/AIDS-related-lymphoma/patient/
Also available in Spanish http://www.cancer.gov/espanol/pdq/tratamiento/linfoma-y-SIDA/patient/
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MedlinePlus: Bone Marrow Transplantation(National Library of Medicine) - http://www.nlm.nih.gov/medlineplus/bonemarrowtransplantation.html
Also available in Spanish http://www.nlm.nih.gov/medlineplus/spanish/bonemarrowtransplantation.html
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Mycosis Fungoides and the Sezary Syndrome (PDQ): Treatment(National Cancer Institute) - http://www.cancer.gov/cancertopics/pdq/treatment/mycosisfungoides/patient/
Also available in Spanish http://www.cancer.gov/espanol/pdq/tratamiento/micosisfungoide/patient
- New Approaches to Treatment(Leukemia & Lymphoma Society) - http://www.leukemia-lymphoma.org/all_page?item_id=4702
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Primary CNS Lymphoma (PDQ): Treatment(National Cancer Institute) - http://www.cancer.gov/cancertopics/pdq/treatment/primary-CNS-lymphoma/patient/
Also available in Spanish http://www.cancer.gov/espanol/pdq/tratamiento/linfoma-sistema-nervioso-central/patient/
- Radiation Therapy for Non-Hodgkins Lymphoma(American Society for Therapeutic Radiology and Oncology) - http://www.rtanswers.org/treatment/disease/non_hodgkins.htm
- Treatment of Extranodal Non-Hodgkin's Lymphoma(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_4X_Treatment_of_Extranodal_Non-Hodgkins_Lymphoma_32.asp
- Treatment of Intermediate Grade Non-Hodgkin's Lymphoma -- Stages I and II(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_4X_Treatment_of_Intermediate_Grade_Non-Hodgkins_Lymphoma_--_Stages_I_and_II_32.asp?sitearea=
- Treatment of Intermediate Grade Non-Hodgkin's Lymphoma -- Stages III and IV and High Grade Lymphomas(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_4X_Treatment_of_Intermediate_Grade_Non-Hodgkins_Lymphoma_--_Stages_III_and_IV_and_High_Grade_Lymphomas_32.asp?sitearea=
- Treatment of People with Waldenstrom Macroglobulinemia(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_4x_Treatment_of_People_with_Waldenstrom_Macroglobulinemia_76.asp?rnav=cri
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Understanding Drug Therapy and Managing Side Effects(Leukemia & Lymphoma Society) - Large PDF file - http://www.leukemia-lymphoma.org/attachments/National/br_1171992654.pdf
Also available in Spanish http://www.leukemia-lymphoma.org/attachments/National/br_1179328567.pdf
- Can Non-Hodgkin Lymphoma Be Prevented?(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_2X_Can_non-Hodgkins_lymphoma_be_prevented_32.asp
- What Are the Risk Factors for Non-Hodgkin Lymphoma?(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_2X_What_are_the_risk_factors_for_non-Hodgkins_lymphoma_32.asp
- What Are the Risk Factors for Waldenstrom Macroglobulinemia?(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_2x_What_Are_The_Risk_Factors_For_Waldenstroms_Macroglobulinemia.asp?rnav=cri
- Integrative Medicine & Complementary and Alternative Therapies As Part of Blood Cancer Care(Leukemia & Lymphoma Society) - Links to PDF - http://www.leukemia-lymphoma.org/attachments/National/br_1150734030.pdf
- Coping with Lymphoma(Lymphoma Research Foundation) - http://www.lymphomafacts.org/site/c.gtJSJbMUIuE/b.1267819/k.608A/Coping_with_Lymphoma.htm
- Relationships and Recovery for Young Adult Lymphoma Survivors(Lymphoma Research Foundation) - http://www.lymphoma.org/site/pp.asp?c=chKOI6PEImE&b=2705045
- Lymphoma, Non-Hodgkin Type: What Happens After Treatment?(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_5X_What_happens_after_treatment_32.asp?sitearea=
- What Happens After Treatment of Waldenstrom Macroglobulinemia?(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_5x_What_Happens_After_Treatment_of_Waldenstroms_Macroglobulinemia.asp?rnav=cri
- Common Types of Non-Hodgkin Lymphoma(Lymphoma Research Foundation) - http://www.lymphoma.org/site/pp.asp?c=chKOI6PEImE&b=1573973
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Cutaneous T Cell Lymphoma(Leukemia & Lymphoma Society) - Links to PDF - http://www.leukemia-lymphoma.org/attachments/National/br_1163608564.pdf
Also available in Spanish http://www.leukemia-lymphoma.org/attachments/National/br_1199384874.pdf
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Waldenstrom's Macroglobulinemia(National Cancer Institute) - http://www.cancer.gov/cancertopics/factsheet/Sites-Types/WM
- Hodgkin's vs. Non-Hodgkin's Lymphoma: What's the Difference?(Mayo Foundation for Medical Education and Research) - http://www.mayoclinic.com/print/lymphoma/AN01209/METHOD=print
- Pain Management(Leukemia & Lymphoma Society) - Links to PDF - http://www.leukemia-lymphoma.org/attachments/National/br_1208959618.pdf
- What You Should Know Before Starting Treatment(Lymphoma Research Foundation) - http://www.lymphoma.org/site/pp.asp?c=chKOI6PEImE&b=1573963
- Atlas of the Body: The Lymphatic System(American Medical Association) - http://www.medem.com/medlb/article_detaillb.cfm?article_ID=ZZZG0S6CGJC&sub_cat=518
- Financial Support(Leukemia & Lymphoma Society) - http://www.leukemia-lymphoma.org/all_page?item_id=4599
- Patient Aid Grant and Healthcare Provider Grant Program(Lymphoma Research Foundation) - http://www.lymphoma.org/site/pp.asp?c=chKOI6PEImE&b=2577325
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ClinicalTrials.gov: Lymphoma(National Institutes of Health) - http://clinicaltrials.gov/search/open/condition=%22Lymphoma%22
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ClinicalTrials.gov: Lymphoma, Non-Hodgkin(National Institutes of Health) - http://clinicaltrials.gov/search/open/condition=%22Lymphoma,+Non-Hodgkin%22
- Antibiotics Work Against Eye Lymphoma(American Cancer Society) - http://www.cancer.org/docroot/NWS/content/NWS_1_1x_Antibiotics_Work_Against_Eye_Lymphoma.asp
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Follicular Lymphoma Treatment Better with Rituximab(National Cancer Institute) - http://www.cancer.gov/clinicaltrials/results/follicular-lymphoma-and-rituximab0505
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Initial Treatment with Rituximab Is a New Standard for Elderly Patients with B-Cell Lymphoma(National Cancer Institute) - http://www.cancer.gov/clinicaltrials/results/elderly-rituximab0706
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Less-Intense Chemotherapy Benefits Some Children with B-Cell Non-Hodgkin Lymphoma(National Cancer Institute) - http://www.cancer.gov/clinicaltrials/results/pediatricNHL0407
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Radiation Might be Avoided for Older Patients with Good Prognosis Non-Hodgkin's Lymphoma(National Cancer Institute) - http://www.cancer.gov/clinicaltrials/results/CHOPalone0207
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Rituximab Helps Patients with Recurrent Lymphomas(National Cancer Institute) - http://www.cancer.gov/clinicaltrials/results/rituximab1106
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Rituximab Improves Response Rate in Mantle Cell Lymphoma(National Cancer Institute) - http://www.cancer.gov/clinicaltrials/results/Rituximab0604
- What's New in Non-Hodgkin Lymphoma Research and Treatment?(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_6X_Whats_new_in_non-Hodgkins_lymphoma_research_and_treatment_32.asp
References and abstracts from MEDLINE/PubMed (National Library of Medicine)
- Article: Signaling through CD80: an approach for treating lymphomas. - http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&dopt=AbstractPlus&list_uids=18620519&tool=MedlinePlus
- Article: Reticuloendothelium malignancy: current role of imaging. - http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&dopt=AbstractPlus&list_uids=18619228&tool=MedlinePlus
- Article: A phase I and pharmacokinetic study of the oral histone... - http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=pubmed&dopt=AbstractPlus&list_uids=18579665&tool=MedlinePlus
- Lymphoma -- see more articles - http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=search&db=pubmed&term=(lymphoma[majr]+NOT+(hodgkin+disease[mh]+OR+lymphoma,non-hodgkin[mh]))+AND+english[la]+AND+humans[mh]+AND+(jsubsetk[text]+OR+review[pt]+OR+guideline[pt]+OR+patient+education+handout[pt]+OR+clinical+trial[pt]+OR+jsubsetaim[text]+OR+jsubsetn[text])+NOT+(letter[pt]+OR+editorial[pt])&doptcmdl=summary&cmd_current=Limits&pmfilter_EDatLimit=last+1+Year&tool=MedlinePlus
- Non-hodgkin lymphoma -- see more articles - http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=search&db=pubmed&term=lymphoma,non+hodgkin[majr]+AND+english[la]+AND+humans[mh]+AND+(review[pt]+OR+guideline[pt]+OR+clinical+trial[pt]+OR+patient+education+handout[pt]+OR+jsubsetk[text]+OR+jsubsetaim[text]+OR+jsubsetn[text])+NOT+(letter[pt]+OR+editorial[pt]+OR+case+reports[pt])&doptcmdl=summary&cmd_current=Limits&pmfilter_EDatLimit=last+1+Year&tool=MedlinePlus
- Learning about Lymphoma: Glossary of Terms(Lymphoma Research Foundation) - http://www.lymphoma.org/site/pp.asp?c=chKOI6PEImE&b=1573585
- Mantle Cell Lymphoma: Glossary(Lymphoma Research Foundation) - http://www.mantlecelllymphoma.org/site/c.mwKUJbNUJrF/b.4017103/k.D4C9/Glossary.htm
- American Cancer Society - http://www.cancer.org/
- Leukemia & Lymphoma Society - http://www.leukemia-lymphoma.org/hm_lls
- Lymphoma Research Foundation - http://www.lymphoma.org/
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National Cancer Institute - http://www.cancer.gov/
- Blood & Marrow Transplant Newsletter(BMT InfoNet) - http://www.bmtinfonet.org/letter.html
- Facts 2007-2008(Leukemia & Lymphoma Society) - Large PDF file - http://www.leukemia-lymphoma.org/attachments/National/br_1182779969.pdf
- Non-Hodgkin Lymphoma Facts & Statistics(Leukemia & Lymphoma Society) - http://www.leukemia-lymphoma.org/all_page?item_id=8965
- What Are the Key Statistics about Non-Hodgkin Lymphoma in Children?(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_1x_What_are_the_key_statistics_for_childhood_non_Hodgkins_lymphoma_9.asp
- Bone Marrow Transplantation (BMT) and Peripheral Blood Stem Cell Transplantation (PBSCT)(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_4x_Bone_Marrow_Transplantation_and_Peripheral_Blood_Stem_Cell_Transplantation_9.asp
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Childhood Cancer: Lymphoma(Nemours Foundation) - http://kidshealth.org/parent/medical/cancer/cancer_lymphoma.html
Also available in Spanish http://kidshealth.org/parent/en_espanol/medicos/cancer_lymphoma_esp.html
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Childhood Non-Hodgkin Lymphoma (PDQ): Treatment(National Cancer Institute) - http://www.cancer.gov/cancertopics/pdq/treatment/child-non-hodgkins/patient/
Also available in Spanish http://www.cancer.gov/espanol/pdq/tratamiento/no-hodgkin-infantil/patient/
- Do We Know What Causes Non-Hodgkin Lymphoma in Children?(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_2x_Do_we_know_what_causes_childhood_non_hodgkins_lymphoma_9.asp?rnav=cri
- How Is Childhood Non-Hodgkin Lymphoma Treated?(American Cancer Society) - http://www.cancer.org/docroot/cri/content/cri_2_2_4x_how_is_childhood_non-hodgkins_lymphoma_treated_9.asp
- How Is Non-Hodgkin Lymphoma in Children Diagnosed?(American Cancer Society) - http://www.cancer.org/docroot/cri/content/cri_2_4_3x_how_is_childhood_non_hodgkins_lymphoma_diagnosed_9.asp
- How Is Non-Hodgkin Lymphoma in Children Staged?(American Cancer Society) - http://www.cancer.org/docroot/cri/content/cri_2_4_3x_how_is_childhood_non_hodgkins_lymphoma_staged_9.asp
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Long-Term and Late Effects of Treatment for Childhood Leukemia or Lymphoma(Leukemia & Lymphoma Society) - Links to PDF - http://www.leukemia-lymphoma.org/attachments/National/br_1184160690.pdf
Also available in Spanish http://www.leukemia-lymphoma.org/attachments/National/br_1208890616.pdf
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Some Kinds of Cancer Kids Get(Nemours Foundation) - http://kidshealth.org/kid/health_problems/cancer/cancer_kinds.html
Also available in Spanish http://kidshealth.org/kid/en_espanol/enfermadades/cancer_kinds_esp.html
- What Are the Risk Factors for Non-Hodgkin Lymphoma in Children?(American Cancer Society) - http://www.cancer.org/docroot/cri/content/cri_2_4_2x_what_are_the_risk_factors_for_childhood_non_hodgkins_lymphoma_9.asp
- What's New in Non-Hodgkin Lymphoma in Children Research and Treatment?(American Cancer Society) - http://www.cancer.org/docroot/CRI/content/CRI_2_4_6x_Whats_new_in_childhood_non_hodgkins_lymphoma_research_and_treatment_9.asp
- Non-Hodgkin's Lymphoma(Nemours Foundation) - http://kidshealth.org/teen/diseases_conditions/cancer/non_hodgkins.html
- Hodgkin's Disease - http://www.nlm.nih.gov/medlineplus/hodgkinsdisease.html
- Cancers - http://www.nlm.nih.gov/medlineplus/cancers.html
- Immune System - http://www.nlm.nih.gov/medlineplus/immunesystem.html
The primary NIH organization for research on Lymphoma is the National Cancer Institute - http://www.nci.nih.gov/