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Fundamentals
On a multi-PI application, you need to act as a full-fledged PI.
Science drives the decision for choosing multiple PIs.
You may forfeit your status as a new PI.

Contact your program officer early.

As a new investigator, you may consider a multiple PI application as an entree into NIH funding. The appeal: you can join a group of experienced investigators, and you will not have to write an entire application.

While those statements are true, the choice is more demanding.

  • First consider the science, which drives the decision. A multiple PI application is appropriate for collaborative projects that have distinct subprojects addressing a core objective or theme.
  • It may be harder to succeed with a multiple PI application.
  • As part of a multiple PI application, you are a full-fledged principal investigator. That means you must be fully in charge of at least one of the project's research aims, and your project must be significant enough to stand on its own.
  • For most award types, you are no longer considered "new," after the project is funded. For a list of exceptions, see Are You "New"?
  • When submitting a multiple PI application, you are not "new" unless all the other PIs also meet NIH's new investigator definition.

Contact your program officer as soon as you can to discuss whether the multi-PI approach is appropriate and beneficial for you.

For details, read Take Heed -- You Might Want to Avoid a Multiple PI Application in the NIH Grant Cycle: Application to Renewal.

Find more information online:

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