Aimee D’Aloisio

Women’s Health

Aimee D’Aloisio
Predoctoral Fellow

Tel (919) 541-3253
Fax (919) 541-2511
daloisio@niehs.nih.gov

Curriculum Vitae (http://www.niehs.nih.gov/research/atniehs/labs/epi/women/staff/daloisio/daloisio_cv.pdf)   P.O. Box 12233
Mail Drop A3-05
Research Triangle Park, North Carolina 27709
Delivery Instructions

• Studies
• Selected Publications

Aimee D'Aloisio's research at NIEHS has focused on the etiology of uterine fibroids. Under the mentorship of Donna Baird, Ph.D, D’Aloisio used data from the NIEHS Uterine Fibroid Study to explore the association of alcohol intake with uterine fibroids. Bayesian methods developed by David Dunson, Ph.D., further support her analysis that alcohol intake is involved in the onset rather than the progression of uterine fibroids (D'Aloisio et al., 2007). Increase in incidence of uterine fibroids was evident for those reporting intake of 0.5 to 2 drinks per week among Caucasian women; however, among African-American women, the increase occurred principally for those reporting at least seven drinks per week.

D'Aloisio’s dissertation research involves the relationship of insulin-like growth factor-1 (IGF-1) and IGF binding protein-3 (IGFBP-3) polymorphisms and estimated haplotypes with the prevalence and growth of uterine fibroids using data and stored blood specimens from the NIEHS Uterine Fibroid Study. Secondarily, she is examining whether the IGF-I and IGFBP-3 polymorphisms and estimated haplotypes predict IGF-I and IGFBP-3 plasma levels. Her research will advance the understanding of the biological mechanisms that cause uterine fibroids and may help explain racial disparities in their prevalence and morbidity.

Studies

• Uterine Fibroid Study
  (http://niehs.nih.gov/research/atniehs/labs/epi/studies/ufs/index.cfm)The Uterine Fibroid Study was designed to determine the prevalence of fibroids, identify risk factors for fibroids, identify biological changes in tumor tissue and describe women's experience of symptoms and their change over time.

Selected Publications

1. Mallin K, McCann K, D'Aloisio A, Freels S, Piorkowski J, Dimos J, Persky V. Cohort mortality study of capacitor manufacturing workers, 1944-2000. Journal of Occupational & Environmental Medicine 46:565-76, 2004. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15213519) [Full Text] (http://gateway.ut.ovid.com/gw2/ovidweb.cgi?QS=ULtqI5KehGzetNREva8UQuN3o3PkV0WJAhVdqhpcQzbtsysz7blLixEocRNBxojbE2IVza%2f%2fOzfuEA8mZ7r0I2iSiO7FlXlrIDLfnIqfwECIxVc1rZjpTUykmVqE1e02kGz94wL31pP2hJPV5dpesxJyoIzGbFYo_9gGCVgULjR3yG0Ww)
2. D'Aloisio AA, Baird DD, Dunson DB, Schroeder JC, et al. Association of alcohol intake with incidence of uterine leiomyomata among African American and Caucasian women. Cancer Epidemiology Biomarkers Prevention. Review, 2007.
3. Ringel-Kulka T, D'Aloisio AA, West SL, Waller AE, et al. Population-based drug-induced anaphylactoid reaction in children and adolescents captured by South Carolina Emergency Room Hospital Discharge Database (2000-2002). Pharmacoepidemiology and Drug Safety. Submitted, 2006.

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