Clinical Trials
Post-Traumatic Stress Disorder (PTSD)
Featured Studies
Featured studies include only those currently recruiting participants. They are listed according to the date they were added to the ClinicalTrials.gov registry, with the most recent studies appearing first.
Effectiveness of Three Different Psychotherapies for Chronic Post-Traumatic Stress Disorder.
Interventional study. This study will examine whether interpersonal psychotherapy is as effective in treating post-traumatic stress disorder as the established therapies of prolonged exposure and relaxation. Ages 18-65. Location in New York, NY.
- Effectiveness of a Web-Based Intervention for Guardians of Children Whose One Parent Has Murdered the Other.
Interventional study. This study will determine whether a specialized Web site geared for the guardians of children whose one parent has murdered the other can increase guardian capabilities, reduce guardian stress, and improve child behavior and mental health. Ages 18 and over. Location in Charlottesville, VA.
- Effectiveness of Cognitive Behavioral Couples Therapy for Post-Traumatic Stress Disorder.
Interventional study. This study will evaluate the effectiveness of cognitive behavioral couples therapy designed for post-traumatic stress disorder in reducing symptoms of post-traumatic stress disorder and in improving relationship functioning. Ages 18-65. Location in Boston, MA.
- Effectiveness of Propranolol For Treating People With Post-Traumatic Stress Disorder.
Interventional study. This study will evaluate the effectiveness of propranolol in reducing symptoms of distress in people with post-traumatic stress disorder. Ages 18-50. Location in New York, NY.
- Effectiveness of an Adaptive Treatment Model for At-Risk Family Caregivers.
Interventional study. This study will develop and evaluate the effectiveness of an adaptive treatment model for reducing the stress of, and burden on, family members caring for a person with dementia. Ages 18 and over. Location in Cleveland, OH.
- Effectiveness of Trauma-Focused Cognitive Behavioral Therapy in Treating Children With Post-Traumatic Stress Disorder.
Interventional study. This study will compare the effectiveness of trauma-focused cognitive behavioral therapy versus standard care in treating children with post-traumatic stress disorder. Ages 8-18. Location in New York, NY.
- Cognitive Behavioral Therapy for Treating Recently Abused Women With Post-Traumatic Stress Disorder.
Interventional study. This study will evaluate the effectiveness of a brief cognitive behavioral treatment, Helping to Overcome PTSD through Empowerment, in treating abused women with post-traumatic stress disorder who are living in shelters. Ages 18 and over. Location in Akron, OH.
- Evaluating the Effects of Stress in Pregnancy.
Evaluation study. This study will evaluate pregnant women with a past or current diagnosis of depression or anxiety to gain a better understanding of how these disorders can affect an infant's development, both during and after pregnancy. Ages 18-45. Location in Atlanta, GA.
- Cognitive Behavioral Treatment for Post-Traumatic Stress Disorder in People With Additional Serious Mental Illnesses.
Interventional study. This study will evaluate the effectiveness of tailored cognitive behavioral therapy in treating post-traumatic stress disorder in people with additional mental illnesses. Ages 18 and over. Locations in New Brunswick, NJ; Newark, NJ.
- Comparing Behavioral Therapies for Treating Adolescents With Post-Traumatic Stress Disorder Related to Sexual Abuse.
Interventional study. This study will evaluate the comparative effectiveness of prolonged exposure therapy and supportive counseling in treating adolescents with post-traumatic stress disorder related to childhood sexual abuse or assault. Ages 13-18. Location in Philadelphia, PA.
- Development of Magnetic Resonance Imaging Techniques for Studying Mood and Anxiety Disorders.
Evaluation study. This study is intended to help develop new MRI imaging techniques for studying mood and anxiety disorders. Ages 18-50. Location in Bethesda, MD.
- Cognitive Behavioral Therapy Versus Sertraline in the Treatment of Post-Traumatic Stress Disorder.
Interventional study. This study will evaluate which parts of the brain are affected by treatment with behavioral therapy versus medication therapy in people with post-traumatic stress disorder. Ages 18-55. Location in New York, NY.
- Substance P Antagonist in the Treatment of Posttraumatic Stress Disorder.
Interventional study. This study, conducted at the NIH and the Mount Sinai School of Medicine, will examine the effectiveness of a substance P or NK1 antagonist study drug known as GR205171 in treating the symptoms of posttraumatic stress disorder (PTSD). Ages 18-65. Locations in Bethesda, MD; New York, NY.
- Effectiveness of Virtual Reality Exposure Therapy and D-Cycloserine to Treat Iraq War Veterans With Post-Traumatic Stress Disorder.
Interventional study. This study will determine whether a combination of virtual reality exposure therapy and D-cycloserine will reduce post-traumatic stress disorder symptoms in Iraq war veterans. Ages 21-65. Location in Atlanta, GA.
- Cognitive Behavioral Therapy for Post-Traumatic Stress Disorder in Homeless Women.
Interventional study. This study will determine the effectiveness of cognitive behavioral therapy in treating post-traumatic stress disorder in homeless women. Ages 18 and over. Location in , .
- Patient-Centered Collaborative Care for Preventing Post-Traumatic Stress Disorder After Traumatic Injury.
Interventional study. This study will evaluate the effectiveness of patient-centered collaborative care that combines behavioral therapy and drug therapy as compared to usual care in reducing symptoms of post-traumatic stress disorder in people who have survived a traumatic injury. Ages 18 and over. Location in Seattle, WA.
- Effectiveness of an NK1 Antagonist in Decreasing Symptoms of Post-Traumatic Stress Disorder.
Interventional study. This study will evaluate the effectiveness of the Nk1 antagonist, GR205171, as compared to placebo, in improving overall PTSD symptoms. Ages 18-65. Location in New York, NY.
- Prazosin for Treating Noncombat Trauma Post-Traumatic Stress Disorder.
Interventional study. This study will evaluate the effectiveness of prazosin in treating post-traumatic stress disorder caused by noncombat trauma in individuals taking selective serotonin reuptake inhibitors. Ages 18 and over. Location in Seattle, WA.
- Treating Post Traumatic Stress Disorder in Children Exposed to Domestic Violence.
Interventional study. This study will determine whether trauma-focused cognitive behavioral therapy (TF-CBT) is more effective than child-centered therapy (CCT) in reducing post traumatic stress disorder (PTSD) in children exposed to domestic violence (DV). Ages 7-14. Location in Pittsburgh, PA.
- Effect of Propranolol on Preventing Post-Traumatic Stress Disorder.
Interventional study. This study will assess the effectiveness of taking propranolol soon after a traumatizing incident in reducing the incidence and severity of post-traumatic stress disorder in acutely traumatized individuals. Ages 18-55. Location in Boston, MA.
- Comparison of Two Treatments for Post-Traumatic Stress Disorder.
Interventional study. This study will compare the short- and long-term effectiveness of two different treatments for people with post-traumatic stress disorder. Ages 18-65. Locations in Cleveland, OH; Seattle, WA.
- Psychobiological Mechanisms of Resilience to Trauma.
Evaluation study. This study will evaluate brain changes and psychological characteristics of people who are resilient to trauma. Ages 18 and over. Locations in Washington, DC; Bethesda, MD.
- Brain Function in Mentally Ill Adolescents.
Evaluation study. The purpose of this study is to use brain imaging technology to examine the brain activity of adolescents with post-traumatic stress disorder (PTSD) and/or major depressive disorder (MDD) before and after treatment. Ages 7-18. Locations in Newark, DE; Bethesda, MD.
Search ClinicalTrials.gov for other NIH studies on Post-Traumatic Stress Disorder (PTSD).
