Launching a Global Alliance for Pharmacogenomics |
|
April 14, 2008 • National Institute of General Medical SciencesU.S. and Japanese scientists partner to study genetic factors that influence the safety and effectiveness of medicines. |
Gene Expression Differences Affect Response to Drugs, Infections |
|
February 28, 2008 • University of Chicago Medical CenterResearchers in the NIGMS-funded Pharmacogenetics Research Network have found that differences in gene expression levels between population groups can affect how they respond to drugs or fight off specific infections. |
PGRN Researchers Question Need for Genetic Tests in All Cases |
|
August 28, 2007 • University of North Carolina at Chapel HillPeople taking low doses of the cancer drug irinotecan need not undergo genetic testing first, say NIGMS-funded researchers. |
Pharmacogenetics Guides Dosing of Common Blood Thinner |
|
August 16, 2007 • Food and Drug AdministrationWork by investigators affiliated with the NIH Pharmacogenetics Research Network has led to changes in the prescribing information of a widely used blood-thinning drug, warfarin (Coumadin). |
Variations in Genes Linked to Toxicity of Leukemia Therapy |
|
May 11, 2007 • St. Jude Children's Research HospitalAn NIGMS-funded study has discovered variations in certain genes that make some children with leukemia susceptible to toxic side effects from common chemotherapy drugs. |
Hints for Better Care of Leukemia Survivors |
|
March 20, 2007 • St. Jude Children's Research HospitalThe longest follow-up study ever done on children with acute lymphoblastic leukemia, supported in part by NIGMS, identifies risks for survivors later in life. |
Large Study Links Mutations to Leukemia |
|
March 7, 2007 • St. Jude Children's Research HospitalNIGMS-funded researchers scanned 350,000 locations across the genome of 242 pediatric patients with acute lymphoblastic leukemia to identify new mutations that contribute to this common childhood cancer. |
Computer Tool Helps Spot Risky Mutations |
|
February 15, 2007 • Johns Hopkins UniversityNIGMS-funded researchers have created a computer tool to help predict which genetic mutations might affect a person's risk for cancer. |
Current Cancer Therapy May Soon be Obsolete |
|
April 18, 2006 • Washington UniversityFindings made by NIGMS-supported investigators suggest that traditional cancer treatments, which base drug regimens on a tumor's anatomical location, should eventually be replaced with therapies based on a tumor's pharmacologic profile. |
NIH Awards Grant to Study Pharmacogenetics of Nicotine Addiction and Treatment |
|
January 25, 2006 • SRI InternationalSRI International and the University of California, San Francisco, have been awarded $10 million to study the genetic basis for variation in response to medications for tobacco dependence. The new program will be part of the Pharmacogenetics Research Network (PGRN). |
Genes' Influence on Drugs May Affect Health-Care Quality |
|
January 4, 2006 • Washington UniversityChances are good that a medication you take is one of several drugs that can be affected by genetic factors, according to a team of NIGMS-supported researchers. |
Pharmacogenetics Test Licensed to Mayo Clinic |
|
December 21, 2005 • University of ChicagoResearchers supported through the NIH Pharmacogenetics Research Network have licensed a genetic test for patients with colorectal cancer to the Mayo Clinic. The agreement will make the test available to patients nationwide starting this month. |
Tamoxifen Benefit Tied to Inherited Gene |
|
December 16, 2005 • Mayo ClinicOne of the most commonly administered drugs for breast cancer, tamoxifen, may not be as effective for women who inherit a common genetic change, according to an NIGMS-supported study. |
NIH Renews Network Focused On How Genes Influence Drug Responses |
|
September 28, 2005 • National Institute of General Medical Sciences |
NIGMS Awards $10 Million for Pharmacogenetics Research |
|
August 29, 2005 • Washington University in St. LouisNIGMS has awarded $10 million to researchers investigating how well anti-cancer therapies work in different patients. The funds will further work begun in 2001 as part of the NIGMS-supported Pharmacogenetics Research Network, a nationwide collaboration of scientists. |
UF Researcher Gets $11 Million To Study Genes, Blood Pressure Drugs |
|
August 18, 2005 • University of Florida |
Mayo Clinic Receives $12.6 Million from NIH to Research Pharmacogenomics |
|
July 26, 2005 • Mayo Clinic |
$15 Million Grant Extends Study of How Genes Affect Cancer Chemotherapy |
|
July 13, 2005 • University of Chicago Medical Center |
Genetic Variation Alters Response to Common Anti-Clotting Drug |
|
June 2, 2005 • National Institute of General Medical SciencesVariations in a gene involved in blood clotting may explain why certain people require a lower or higher dose to get the full benefits of the anticoagulant drug warfarin, say NIGMS-funded researchers at the University of Washington in Seattle and Washington University in St. Louis.
|
New Insights Into Why Medicines Work Differently Among People |
|
April 2, 2002 • National Institute of General Medical Sciences |
Pharmacogenetics Research Network Chooses Journal to Publish PharmGKB Data |
|
November 9, 2001 • National Institute of General Medical Sciences |
Simple Breath Test Predicts Gene-Linked Drug Response |
|
October 26, 2001 • National Institute of General Medical Sciences |
NIH Pharmacogenetics Research Network Announces New Members |
|
September 4, 2001 • National Institute of General Medical Sciences |
Pharmacogenetics Research Network Seeks Journal Partnership |
|
June 1, 2001 • National Institute of General Medical Sciences |
NIH Hosts First Annual Meeting of the Pharmacogenetics Research Network |
|
April 10, 2001 • National Institute of General Medical Sciences |
NIH To Study How Genes Affect Response to Medicines |
|
August 8, 2000 • National Institute of General Medical Sciences |
First Awards Made in NIH Effort to Understand How Genes Affect People's Responses to Medicines |
|
April 4, 2000 • National Institute of General Medical Sciences |