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The Protein Structure Initiative, Five Years Later
New technologies and streamlined processes set the stage for PSI Phase 2
Email: John Norvell - norvellj@nigms.nih.gov; Jeremy M Berg - bergj@nigms.nih.gov The Scientist 2005, 19(20):30
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Five years have passed since the National Institutes of Health launched the Protein Structure Initiative (PSI), a 10-year, $600 million effort to accelerate structural genomics. The project's pilot phase emphasized technical development and ended earlier this year; the second (production) phase is now underway. Now, $270 million dollars and 1,200 structures later, it is instructive to reflect and see what we have learned.
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