The illustration below is from Vol 7 pp. 827-32, 2001 of Nature Medicine
![Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis](https://webarchive.library.unt.edu/eot2008/20080916103912im_/http://www.niaaa.nih.gov/NR/rdonlyres/83AC52F8-45CE-497B-98AE-5745B40FD575/0/cb1_endocann_med.gif)
Endogenous anandamide in monocytes from cirrhotic and control rats. A representative LC/MS analysis of samples extracted from the monocyte fraction of 20 ml pooled blood of sham-operated (a) and cirrhotic (b) rats. Two selected ions were monitored simultaneously: m/z 356.2 for d8-anandamide ions as internal standard (upper panels) and m/z 348.2 for anandamide ions (bottom panels). Numbers at the peaks indicate the Liquid chromatography (LC) retention time of the compounds in minutes.
Updated: August 2002