Mission Statement:
- Focuses on the neural circuitry involved in the control of appetite and appetitive behavior, including ethanol-drinking behavior, with an emphasis on endogenous cannabinoids and their receptors;
- research in vascular biology, including the role of the vascular endothelium as a site of action for the cardiovascular effects of ethanol.
Staff:
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Selected Publications:
Osei-Hyiaman D, Depetrillo M, Pacher P, Liu J, Radaeva S, Bátkai S, Harvey-White J, Offertáler L, Wang L, Kunos G: Endocannabinoid acting at hepatic CB1 receptors regulates fatty acid synthesis: role in diet-induced obesity. J Clin Invest 115:1298-1305, 2005. 
[ PDF ]
Bátkai S, Pacher P, Osei-Hyiaman D, Radaeva S, Liu J, Harvey-White J, Offertáler L, Mackie K, Rudd MA, Bukoski RD, Kunos G: Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension. Circulation 110:1996-2002, 2004. [ PDF ]
Wang L, Liu J, Harvey-White J, Zimmer A, Kunos G: Endocannabinoid signaling via CB1 receptors is involved in ethanol preference and its age-dependent decline in mice. Proc Natl Acad Sci USA (track II) 100:1393-1398, 2003. [ PDF ]
Liu J, Bátkai S, Pacher P, Harvey-White J, Wagner JA, Cravatt BF, Gao B, Kunos G: Lipopolysaccharide induces anandamide synthesis in macrophages via CD14/MAPK/phosphoinositide 3-kinase/NF-kappaB independently of platelet-activating factor. J Biol Chem 278:45034-45039, 2003. [ PDF ]
Di Marzo V, Goparaju SK, Wang L, Liu J, Bátkai S, Járai Z, Fezza F, Miura GI, Palmiter RD, Sugiura T, Kunos G: Leptin-regulated hypothalamic endocannabinoids acting at CB1 receptors are involved in maintaining food intake. Nature (London) 410:822-825, 2001. [PDF]
Bátkai S, Járai Z, Wagner JA, Goparaju SK, Varga K, Liu J, Wang L, Mirshahi S, Khanolkar AD, Makriyannis A, Urbaschek R, Garcia N Jr, Sanyal AJ, Kunos G: Endocannabinoids acting at vascular CB1 receptors mediate the vasodilated state in advanced liver cirrhosis. Nature Medicine 7:827-832, 2001. [PDF]
Alcohol publications can also be found using ETOH Database.
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