Mary-Anne Enoch, M.D.,
301.496.2727
maenoch@mail.nih.gov

Colin Hodgkinson, Ph.D.,
301.443.7633
chodg@mail.nih.gov

A Fogarty Fellow, trained in psychiatry with professors Liliana Dell’Osso and Alessandrom Rotondo (Formerly LNG) in Pisa. Dr. Ducci is interested in behavioral dyscontrol and the role of genotype in refining diagnosis. She studies phenotypes for linkage in LNG datasets most suitable for this purpose. She has constructed large SNPlex-based panels, including panels for serotonin-related genes such as. HTR1B HTR2A, and HTR2C that were previously studied at low marker density or perhaps with one functional marker, cannabinoid genes and other genes.

A Fogarty Research Fellow, was trained in the Neurogenetics and Human Genetics Group at Shanghai Jiaotong University where she worked on genetics of schizophrenia and previously received her Ph.D. Her main interests are in epigenetics, pharmacogenetics and array-based gene expression.

Is a bioinformatics and analytical IT tools resource for all members of LNG.  He is in the DNA/Data Core where he leads genome informatics.  He trained at NCI and joined the lab in 2005 following his work in sequencing the rice genome published in Nature at TIGR.

Manages all clinical genetic database and analytical IT for LNG, as described in DNA/Data Core. She is facile in database and data management tools, and in programming. She is a bioinformatics and analytical IT tools resource for all members of LNG.  She joined LNG in 2004, from Celera.

Systems/Network Specialist and Robotics.. She designed, installed and manages all LNG’s servers which includes a large number of DNA sequencers and dHPLC machines continually collecting data to the servers. She has also created and managed certain clinical phenotype/genotype databases. She now works on DNA robotics and other “front-end” aspects of high throughput genetic analysis. She is extremely facile in systems management, including hardware issues, and programming.

A molecular biologist, performs all DNA sequencing and sequence variant detection in the DNA Core. In an independent project, Dr. Zhou resequenced TPH2 and found haplotype-based linkage of this gene, which encodes the rate-limiting enzyme for serotonin synthesis, to suicidality and impulsive behaviors and 5HIAA levels.

An extraordinarily talented tissue culture technician, manages the front-end of multiple collaborations requiring preparation of DNA and/or lymphoblastoid cell lines. She performs or supervises all the primary cell culture, DNA extractions from cells and blood, and cell storage – including off-site backup. She assists in the construction of DNA panels for linkage studies. Her position is broad in scope and responsibility in that she is the direct, and frequent point of interaction with many collaborating investigators.

A biologist technician, has a wide range of expertise in molecular biology, ranging from cloning, sequencing, and transfection and expression studies to automated genotyping. In the DNA/Data Core, he leads the clinical genotyping under CLIA (Clinical Laboratory Improvement Act) standards.