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University of Florida

University of Florida

General Clinical Research Center
J. Hillis Miller Health Center, Room 3245 Shands
1600 SW Archer Road
Gainesville, FL 32610-0215

Web site: www.gcrc.ufl.edu external link, opens in new window

Grant No. M01 RR00082

Special Resources, Instruments, or Services

Computerized diet intake analysis
Dinamap blood pressure monitoring
DNA isolation
Gas chromatograph/mass spectrometry
Glucose/lactate analyses
Indirect calorimetry
Liquid chromatography/mass spectrometry
Metabolic kitchen
Scintillation counting
Sleep research room
Statistical planning, data management, and analysis services

Major Areas of Investigation

Clinical Pharmacology: Pharmacokinetics of beta-adrenergic blockers; biotransformation and pharmacokinetics of dichloroacetate.

Endocrinology and Metabolism: Diagnosis, prevention and treatment of insulin-dependent diabetes and other autoimmune diseases; course and treatment of congenital lactic acidosis.

Environmental Health: Biotransformation and toxicology of chlorinated hydrocarbons.

Exercise Physiology: Modulation of cardiac risk factors by graded exercise; exercise-induced changes in homocysteine metabolism and insulin resistance; exercise endurance in mitochondrial diseases.

Gastroenterology: Isotopic breath tests for diagnosis of intestinal bacterial overgrowth and malabsorption; new drug therapy for pancreatitis and hepatitis C.

Gene Therapy: Administration of adeno-associated viral vectors for congenital diseases.

Neonatology: Maternal-fetal HIV transmission; prevention of nosocomial infections in preterm neonates; placental transport and metabolism; biology of cytokine receptors; GCSF therapy in neonates; identification and functional significance of erythropoietin receptors in the fetus; glutamine synthetase and glutaminase activities in premature infants.

Nursing: Coping effectiveness of parents whose children have inborn errors of metabolism.

Nutrition: Folate and pyridoxine nutritional status in women; nutritional regulation of one-carbon metabolism; gene polymorphisms affecting homocysteine metabolism.

Pulmonary Diseases: Treatment of cystic fibrosis; alpha-1 antritypsin deficiency and asthma.

Rheumatology: Pathobiology of systemic lupus erythematosus; treatment of fibromyalgia.

Contact Information

For information about this GCRC and how to access its resources, please contact:

Administrative Manager
Ann Coutu
352-265-8909; Fax: 352-265-8910
E-mail: coutua@gcrc.ufl.edu

Program Director
Peter W. Stacpoole, Ph.D., M.D.
352-265-8909; Fax: 352-265-8910
E-mail: stacpool@gcrc.ufl.edu

Principal Investigator
Bruce C. Kone, M.D.
352-273-7500; Fax: 352-846-3299
E-mail: bkone@ufl.edu

Associate Program Director
Mark Brantly, M.D.
352-846-2701; Fax: 352-846-3299
E-mail: brantml@medicine.ufl.edu

Associate Program Director
Desmond Schatz, M.D.
352-334-1390; Fax: 352-846-2147
E-mail: schatzda@peds.ufl.edu

Research Subject Advocate
H. Robert Kolb, R.N., B.S., C.C.R.C.
352-265-0680 x43715; Fax: 352-265-8910
E-mail: Kolbb@gcrc.ufl.edu

GCRC Advisory Committee Chairperson
N. Lawrence Edwards, M.D.
352-265-0239; Fax: 352-338-9879
E-mail: edwarnl@medicine.ufl.edu

Nurse Manager
Teresa d'Angelo, R.N., B.S.N., C.C.R.C.
352-265-0032; Fax: 352-338-9843
E-mail: danget@shands.ufl.edu

Core Laboratory Director
Tim Garrett, Ph.D.
352-392-2321; Fax: 352-846-0990
E-mail: garrett@gcrc.ufl.edu

Nutrition Research Manager
Meena Shankar, M.S., R.D.
352-265-0680 x43713; Fax: 352-338-9843
E-mail: shankarm@gcrc.ufl.edu

Biostatistician
Johnathan Shuster, Ph.D.
352-294-0004; Fax: 352-392-4168
E-mail: jshuster@gcrc.ufl.edu

Informatics Manager
Douglas W. Theriaque, M.S.
352-265-8909 x46233; Fax: 352-265-8910
E-mail: theriaque@gcrc.ufl.edu