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University of Connecticut (Farmington)

University of Connecticut

General Clinical Research Center
University of Connecticut Health Center
263 Farmington Avenue
Farmington, CT 06030-3805

Web site: http://gcrc.uchc.edu external link, opens in new window

Grant No. M01 RR006192

Special Assays, Services, or Tests

Bone marker immunoassays: Free deoxypyridinoline crosslinks, crosslinked C-telopeptide, and N-telopeptide of type I collagen, osteocalcin, bone-specific alkaline phosphatase, N-terminal propeptide of type I collagen Hormones, growth factors, cytokines Molecular biology: RNA and DNA extraction from tissue and blood; quantitative PCR; microarrays; quantitative reverse-transcriptase PCR

Major Areas of Investigation

Cardiology: Atrial fibrillation; hypertension; congestive heart failure.

Endocrinology: Oncogenes of adrenal and thyroid tumors; effect of sex hormones on calcium and bone turnover in older women and men; bone loss and its treatment in men with prostate cancer.

Gastrointestinal Diseases: Acute intermittent porphyria; hepatitis C.

Genetic Diseases: Primary cortisol resistance; genetic abnormalities in glaucoma; osteoporosis; osteogenesis imperfecta; lysosomal storage disorders.

Infectious Diseases: Lyme and other tick-borne diseases; AIDS; influenza.

Obstetrics and Gynecology: Smoking cessation and pregnant women.

Oncology: National Surgical Adjuvant Breast and Bowel Project prevention and treatment trials; treatment of chronic myelogenous leukemia, breast cancer, cervical disease with heat shock protein immunotherapy.

Pediatrics: AIDS, Children's Cancer Group protocols; tick-borne diseases; Crohn's disease and bone, asthma.

Psychiatry: Etiology and pathophysiology of alcohol, cocaine, and opioid dependence, including neuroendocrinologic, neuropsychological, and molecular genetic studies; pharmacological treatment of alcohol dependence; physiological measures of risk and molecular genetic studies of schizophrenia; psychotherapy of alcohol and drug dependence and pathological gambling.

Rheumatology: Sjogren's syndrome; scleroderma.

Contact Information

For information about this GCRC and how to access its resources, please contact:

Administrative Director
Lesley Mancini, M.B.A.
860-679-2880; Fax: 860-679-1454
E-mail: lmancini@uchc.edu

Program Director
Henry R. Kranzler, M.D.
860-679-4151; Fax: 860-679-1316
E-mail: kranzler@psychiatry.uchc.edu

Principal Investigator
Bruce Koeppen, M.D., Ph. D.
860-679-2385; Fax: 860-679-1012
E-mail: koeppen@nso.uchc.edu

Associate Program Director
Lawrence Raisz, M.D.
860-679-3851; Fax: 860-679-1454
E-mail: raisz@nso.uchc.edu

Associate Program Director
Cheryl Oncken, M.D.
860-679-3425; Fax: 860-679-1250
E-mail: Oncken@nso2.uchc.edu

Associate Program Director
Anne Kenny, M.D.
860-679-4928; Fax: 860-679-1307
E-mail: Kenny@nso1.uchc.edu

Research Subject Advocate
Kathleen Salomone, A.P.R.N.
860-679-3276; Fax: 860-679-1454
E-mail: salomone@nso.uchc.edu

GCRC Advisory Committee Chairperson
Victor Hesselbrook, Ph.D.
860-679-3266; Fax: 860-679-4077
E-mail: hesslb@psychiatry.uchc.edu

Core Laboratory Director
Jonathan Covault, M.D., Ph.D.
860-679-3681; Fax: 860-679-4077
E-mail: covault@psychiatry.uchc.edu

Nurse Manager
Tom Kiely, R.N., C.C.R.P.
860-679-1707; Fax: 860-679-1454
E-mail: Kiely@nso.uchc.edu

Biostatistician
Stephen Walsh, Sc.D.
860-679-5471; Fax: 860-679-5464
E-mail: walsh@nso.uchc.edu

Informatics Director
Khamis Abu-Hasaballah, Ph.D.
860-679-8141; Fax: 860-679-1454
E-mail: khamis@nso.uchc.edu