Selected Publications

Comparative Genomics Group

1. Jin YH, Dunlap PE , McBride SJ, Al-Refai H, Bushel PR, Freedman JH. Global transcriptome and deletome profiles of yeast exposed to transition metals. PLoS Genetics (2008) 4(4):e1000005-. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18437200)
2. Eddins D, Petro A, Pollard N, Freedman JH, Levin ED. Mercury-induced cognitive impairment in metallothionein-1/2 null mice. Neurotoxicology and teratology (2008) 30(2):88-95. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18226494)
3. Boyd WA, McBride SJ, Freedman JH. Effects of genetic mutations and chemical exposures on Caenorhabditis Elegans feeding: Evaluation of a novel, high-throughput screening assay. PLoS ONE (2007) 2(12):e1259-. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18060055)
4. Mattie, M.D. and Freedman, J.H. (2004) Copper-inducible transcription: Regulation by metal- and oxidative stress-responsive pathways. Am. J.Physiol. Cell. Physiol. 286, C293-C301.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14576086)
5. Schwartz, D.A., Freedman, J.H., and Linney, E.A. (2004) Environmental Genomics: A key to understanding biology, pathophysiology, and disease. Hum. Mol. Gen. 13, R217-224.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15358728)
6. Dong, J. Song, M.O., Freedman, J.H. (2005) Identification and characterization of a family of Caenorhabditis elegans genes that are homologous to the cadmium-responsive gene cdr-1. Biochim. Biophys. Acta - Gene Struct. Expression 1727, 16-26.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15652154)
7. Song, M.O and Freedman, J.H. (2005) Activation of mitogen activated protein kinases by PCB126 (3,3',4,4',5-pentachlorobiphenyl) in HepG2 cells. Toxicol. Sci. 84, 308-318.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15647597)
8. Members of the Toxicogenomics Research Consortium (2005) Toxicogenomics Research Consortium: Standardizing gene expression between laboratories and across platforms Nat. Methods 2, 351-356.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15846362)
9. Song, M.O and Freedman, J.H. (2005) Expression of copper-responsive genes in HepG2 cells. Molec. Cell Biochem. 279, 141-147.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16283523)
10. Levin, E.D., Perraut, C., Pollard, N., and Freedman, J.H. (2006) Metallothionein expression and neurocognitive function in mice. Phsyiol Behavio. 87, 513-518.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16430929)
11. Meyer, J.N., Boyd, W.A., Azzam, G.A., Haugen, A.C., Freedman, J.H., and Van Houten, B. (2007) Decline of nucleotide excision repair capacity in aging Caenorhabditis elegans. In Press Genome Biol.
12. Cui Y, McBride SJ, Boyd WA, Alper S, Freedman JH. Toxicogenomic analysis of caenorhabditis elegans reveals novel genes and pathways involved in the resistance to cadmium toxicity. Genome biology 2007 6: R122-R122. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17592649)
13. Dong J, Boyd W, Freedman JH. Molecular characterization of two homologs of the caenorhabditis elegans cadmium responsive gene cdr-1: cdr-4 and cdr-6. Journal of molecular biology 2008 376:621-633. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18177893)