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Agency for Toxic Substances and Disease Registry
Case Studies in Environmental Medicine (CSEM) 

Chromium Toxicity

Course: SS3048
Revision Date: July 2000
Original Date: October 1992
CE Expiration Date: July 6, 2006


Key Concepts

Chromium (III) is an essential nutrient that can be toxic in large doses.
The toxicity of chromium compounds depends on the oxidation state of the metal.
Occupational exposure to chromium (VI) has been associated with increased incidence of lung cancer.
The efficacy of chelation therapy in chromium poisoning has not been proven.

Authorship

ATSDR/DHEP Revision Authors

Diane Drew, RN, MPA; Ifeoma Stella Izuchukwu, MD; Pamela Tucker, MD

ATSDR/DHEP Revision Planners

William Carter, MD; Diane Dennis-Flagler, MPH; Patricia Drehobl, RN, BSN (CDC/PHPPO); Kim Gehle, MD, MPH; Darlene Johnson, RN, BSN, MA; Ralph O'Connor Jr, PhD

Revision Editors

Pamela S. Wigington, Anne A. Olin, BSJ

Original Contributor

Vikas Kapil, DO, MPH

Original Peer Reviewers:

Charles Becker, MD; Jonathan Borak, MD; Joseph Cannella, MD; Bernard Goldstein, MD; Alan Hall, MD; Richard J. Jackson, MD, MPH; Robert Wheater, MS; Brian Wummer, MD

Each content expert for this case study indicated no conflict of interest to disclose with the case study subject matter.

ATSDR Publication No.: ATSDR-HE-CS-2001-0005


Notes

This monograph is one in a series of self-instructional publications designed to increase the primary care provider's knowledge of hazardous substances in the environment and to aid in the evaluation of potentially exposed patients. See the Accreditation section for more information about continuing medical education credits, continuing nursing education units, and continuing education units.


Disclaimer

The state of knowledge regarding the treatment of patients potentially exposed to hazardous substances in the environment is constantly evolving and is often uncertain. In this monograph, ATSDR has made diligent effort to ensure the accuracy and currency of the information presented, but makes no claim that the document comprehensively addresses all possible situations related to this substance. This monograph is intended as an additional resource for physicians and other health professionals in assessing the condition and managing the treatment of patients potentially exposed to hazardous substances. It is not, however, a substitute for the professional judgment of a health care provider. The document must be interpreted in light of specific information regarding the patient and in conjunction with other sources of authority.

Use of trade names and commercial sources is for identification only and does not signify endorsement by the Agency for Toxic Substances and Disease Registry or the U.S. Department of Health and Human Services.


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Revised 2000-07-06.